Sestrin2 protects against cholestatic liver injury by inhibiting endoplasmic reticulum stress and NLRP3 inflammasome-mediated pyroptosis
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Sestrin2 protects against cholestatic liver injury by inhibiting endoplasmic reticulum stress and NLRP3 inflammasome-mediated pyroptosis' 의 참고문헌
p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling
mTOR-dependent role of Sestrin2 in regulating tumor progression of human endometrial cancer
mTOR signaling in growth, metabolism, and disease
Upregulation of sestrin 2 expression via JNK pathway activation contributes to autophagy induction in cancer cells
Uncoupling of ER/mitochondrial oxidative stress in mTORC1hyperactivation-associated skin hypopigmentation
Thrombophlebitis complicating sternocostoclavicular hyperostosis
The involvement of endoplasmic reticulum stress in bile acid-induced hepatocellular injury
The inflammasomes : mechanisms of activation and function
Stress-responsive sestrins link p53 with redox regulation and mammalian target of rapamycin signaling
Sestrins inhibit mTORC1 kinase activation through the GATOR complex
Sestrin2 protects against lethal sepsis by suppressing the pyroptosis of dendritic cells
Sestrin2 protects against acetaminophen-induced liver injury
Sestrin2 inhibits mTORC1 through modulation of GATOR complexes
Sestrin2 as a novel biomarker and therapeutic target for various diseases
Sestrin2 alleviates palmitate-induced endoplasmic reticulum stress, apoptosis, and defective invasion of human trophoblast cells
Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies
Sestrin 2 confers primary resistance to sorafenib by simultaneously activating AKT and AMPK in hepatocellular carcinoma
Sestrin 2 attenuates rat hepatic stellate cell(HSC)activation and liver fibrosis via an mTOR/AMPK-dependent mechanism
Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathway
Salvianolic acid A attenuates endoplasmic reticulum stress and protects against cholestasis-induced liver fibrosis via the SIRT1/HSF1 pathway
SESN2/sestrin 2 induction-mediated autophagy and inhibitory effect of isorhapontigenin(ISO)on human bladder cancers
Roles of TGF-beta in hepatic fibrosis
Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD
Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting
Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo
NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice
NLRP3 inflammasome activation is required for fibrosis development in NAFLD
Molecular pathogenesis of liver fibrosis
Mechanisms of cholestasis
Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3
Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression
Inhibitory effect of Sestrin 2 on hepatic stellate cell activation and liver fibrosis
Inflammasomes and their roles in health and disease
Inflammasome signalling in brain function and neurodegenerative disease
Impaired autophagy promotes bile acid-induced hepatic injury and accumulation of ubiquitinated proteins
Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability
Hepatoprotective role of Sestrin2 against chronic ER stress
Excessive endoplasmic reticulum stress correlates with impaired mitochondrial dynamics, mitophagy and apoptosis, in liver and adipose tissue, but not in muscles in EMS horses
Endoplasmic reticulum stress regulates hepatic bile acid metabolism in mice
Endoplasmic reticulum stress in liver disease
Endoplasmic reticulum stress and NLRP3 inflammasome: Crosstalk in cardiovascular and metabolic disorders
Effect of deoxycholic acid and ursodeoxycholic acid on lipid peroxidation in cultured macrophages
Effect of bile acids on fibroblast proliferation and viability
Effect of S-adenosylmethionine versus tauroursodeoxycholic acid on bile acid-induced apoptosis and cytolysis in rat hepatocytes
ER stress activates the NLRP3 inflammasome : a novel mechanism of atherosclerosis
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
Drug-induced liver injury
Crosstalk of autophagy and apoptosis : Involvement of the dual role of autophagy under ER stress
Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis
Calnexin depletion by endoplasmic reticulum stress during cholestasis inhibits the Na(+)-taurocholate cotransporting polypeptide
Bile acids as metabolic regulators
Bile acidinduced liver toxicity: relation to the hydrophobic-hydrophilic balance of bile acids
Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis
Bile acid toxicity structure-activity relationships : correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line(HET-1A)
Bile acid metabolism and signaling in cholestasis, inflammation, and cancer
Bidirectional role of NLRP3 during acute and chronic cholestatic liver injury
Autophagy is activated for cell survival after endoplasmic reticulum stress
Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes
Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme
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Sestrin2 protects against cholestatic liver injury by inhibiting endoplasmic reticulum stress and NLRP3 inflammasome-mediated pyroptosis'
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