연구동향 분석

Acid sphingomyelinase inhibition improves motor behavioral deficits and neuronal loss in an amyotrophic lateral sclerosis mouse model

Byung Jo Choi Kang Ho Park Min Hee Park Eric Jinsheng Huang Seung Hyun Kim Jae-sung Bae Hee Kyung Jin 2022년

논문상세정보
인용/피인용
' Acid sphingomyelinase inhibition improves motor behavioral deficits and neuronal loss in an amyotrophic lateral sclerosis mouse model' 의 주제별 논문영향력
논문영향력 선정 방법
논문영향력 요약
주제
  • Acid sphingomyelinase
  • Motor behavioral dysfunction
  • Motor neuronal loss
  • amyotrophic lateral sclerosis
  • fus
동일주제 총논문수 논문피인용 총횟수 주제별 논문영향력의 평균
38 0

0.0%

' Acid sphingomyelinase inhibition improves motor behavioral deficits and neuronal loss in an amyotrophic lateral sclerosis mouse model' 의 참고문헌

  • Zn2+-stimulated sphingomyelinase is secreted by many cell types and is a product of the acid sphingomyelinase gene
    Schissel SL [1996]
  • Vascular and neurogenic rejuvenation in aging mice by modulation of ASM
    Park MH [2018]
  • The unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases
    Smith EL [2008]
  • TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
  • TBK1 : a new player in ALS linking autophagy and neuroinflammation
    Oakes JA [2017]
  • Secretory sphingomyelinase in health and disease
    Kornhuber J [2015]
  • Roles and regulation of secretory and lysosomal acid sphingomyelinase
    Jenkins RW [2009]
  • Role of sphingomyelinases in neurological disorders
    Ong WY [2015]
  • Prognostic factors in ALS : a critical review
    Chio A [2009]
  • Potential therapeutic target for aging and age-related neurodegenerative diseases: the role of acid sphingomyelinase
  • Oxidative stress triggers Ca-dependent lysosome trafficking and activation of acid sphingomyelinase
    Xiang Li [2012]
  • Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age-and dose-dependent fashion
    Mitchell JC [2013]
  • Novel FUS/TLS mutations and pathology in familial and sporadic amyotrophic lateral sclerosis
    Hewitt C [2010]
  • Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
    Vance, C. [2009]
  • Mislocated FUS is sufficient for gain-of-toxic-function amyotrophic lateral sclerosis phenotypes in mice
    Shiihashi G [2016]
  • Genetic epidemiology of amyotrophic lateral sclerosis : a systematic review and meta-analysis
    Zou ZY [2017]
  • Functional Inhibitors of Acid Sphingomyelinase(FIASMAs) : a novel pharmacological group of drugs with broad clinical applications
    Kornhuber J [2010]
  • Familial ALS
    Boylan K [2015]
  • FUS regulates autophagy by mediating the transcription of genes critical to the autophagosome formation
    Arenas A [2021]
  • Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis
    Cutler RG [2002]
  • Disrupted autophagy and neuronal dysfunction in C. elegans knockin models of FUS amyotrophic lateral sclerosis
    Baskoylu SN [2022]
  • Discovery of a dual-action small molecule that improves neuropathological features of Alzheimer’s disease mice
    Park MH [2022]
  • Amyotrophic lateral sclerosis
    Rowland LP [2001]
  • Amyotrophic lateral sclerosis
    Hardiman O [2017]
  • Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer’s disease
    Lee JK [2014]
  • Acid sphingomyelinase deficient mice : a model of types A and B Niemann-Pick disease
  • ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects
    Qiu H [2014]
  • ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function
    Sharma A [2016]
  • ALS genetics, mechanisms, and therapeutics : where are we now?
    Mejzini R [2019]
  • ALS genetics : gains, losses, and implications for future therapies
    Kim G [2020]
  • ALS clinical trials review : 20 years of failure. Are we any closer to registering a new treatment?
    Petrov, D. [2017]
  • A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
  • 'Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis