Targeted inhibition of tumor-derived exosomes as a novel therapeutic option for cancer
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Targeted inhibition of tumor-derived exosomes as a novel therapeutic option for cancer' 의 참고문헌
YKT6 expression, exosome release, and survival in nonsmall cell lung cancer
WNT5A induces release of exosomes containing proangiogenic and immunosuppressive factors from malignant melanoma cells
Tumour exosomes from cells harbouring PTPRZ1-MET fusion contribute to a malignant phenotype and temozolomide chemoresistance in glioblastoma
Tumour exosome integrins determine organotropic metastasis
Tumorderived exosomes regulate expression of immune function-related genes in human T cell subsets
Tumor-derived exosomes(TEX)and their role in immuno-oncology
Tumor-derived exosomes induced M2 macrophage polarization and promoted the metastasis of osteosarcoma cells through Tim-3
Tumor-derived exosomes in tumor-induced immune suppression
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway
Tumor-derived exosomes and their role in cancer progression
Tumor microenvironment and therapeutic response
Tumor exosomes expressing Fas ligand mediate CD8+T-cell apoptosis
Therapeutic plasma exchange clears circulating soluble PD-L1 and PD-L1-positive extracellular vesicles
Therapeutic in vivo gene transfer for genetic disease using AAV : progress and challenges
The tumor microenvironment innately modulates cancer progression
The role of exosomal microRNA in cancer drug resistance
The role of Alix in the proliferation of human glioma cells
The frequency of Ras mutations in cancer
The emerging roles of exosomes as EMT regulators in cancer
The effect of tumor-derived exosomes on immune regulation and cancer immunotherapy
The biology, function, and biomedical applications of exosomes
The biology and function of fibroblasts in cancer
Tethering the assembly of SNARE complexes
Targeting regulation of the tumour microenvironment induces apoptosis of breast cancer cells by an affinity hemoperfusion adsorbent
TSG101 promotes the proliferation, migration, and invasion of human glioma cells by regulating the AKT/GSK3beta/beta-Catenin and RhoC/Cofilin pathways
TI-VAMP/VAMP7and VAMP3/cellubrevin : two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways
Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2
Syntaxin 6-mediated exosome secretion regulates enzalutamide resistance in prostate cancer
Syndecan-syntenin-ALIX regulates the biogenesis of exosomes
Suppression of exosomal PD-L1 induces systemic anti-tumor immunity and memory
Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
Sulfisoxazole elicits robust antitumour immune response along with immune checkpoint therapy by inhibiting exosomal PD-L1
Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation
Small molecule-triggered Cas9 protein with improved genome-editing specificity
STAM2 knockdown inhibits proliferation, migration, and invasion by affecting the JAK2/STAT3 signaling pathway in gastric cancer
STAM prolongs clear cell renal cell carcinoma patients’ survival via inhibiting cell growth and invasion
STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes
Role of HLA-G and extracellular vesicles in renal cancer stem cell-induced inhibition of dendritic cell differentiation
Repurposing ketoconazole as an exosome directed adjunct to sunitinib in treating renal cell carcinoma
Ras and exosome signaling
Rab27a and Rab27b control different steps of the exosome secretion pathway
Rab GTPases as coordinators of vesicle traffic
RAB31 marks and controls an ESCRT-independent exosome pathway
Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer
Protein spectrum changes in exosomes after therapeutic plasma exchange in patients with neuromyelitis optica
Potential roles of tumor-derived exosomes in angiogenesis
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
Overview of extracellular vesicles, their origin, composition, purpose, and methods for exosome isolation and analysis
Optimized sgRNA design to maximize activity and minimize offtarget effects of CRISPR-Cas9
New insights into the function of Rab GTPases in the context of exosomal secretion
Nanoparticles as drug delivery systems of RNAi in cancer therapy
Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function
Molecular mechanism of multivesicular body biogenesis by ESCRT complexes
Microenvironmental pH is a key factor for exosome traffic in tumor cells
Membrane fusion : grappling with SNARE and SM proteins
Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castrationresistant prostate cancer cells
Inhibition of tumor growth and metastasis by depletion of vesicular sorting protein Hrs : its regulatory role on E-cadherin and beta-catenin
Inhibition of oncogenic epidermal growth factor receptor kinase triggers release of exosome-like extracellular vesicles and impacts their phosphoprotein and DNA content
Inhibition of neutral sphingomyelinase 2 promotes remyelination
Inhibiting extracellular vesicles formation and release : a review of EV inhibitors
Inclusion biogenesis, methods of isolation and clinical application of human cellular exosomes
In vivo delivery of CRISPR-Cas9 therapeutics : progress and challenges
Immune modulation of T-cell and NK(natural killer)cell activities by TEXs(tumour-derived exosomes)
Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles
Immune cells within the tumor microenvironment : biological functions and roles in cancer immunotherapy
ITGB4-mediated metabolic reprogramming of cancer-associated fibroblasts
ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins
Hypoxic tumor-derived exosomal miR-301a mediates M2 macrophage polarization via PTEN/PI3Kgamma to promote pancreatic cancer metastasis
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes
Hypoxia-stimulated ATM activation regulates autophagy-associated exosome release from cancer-associated fibroblasts to promote cancer cell invasion
Human CD4+ CD39+ regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+ exosomes or CD73+ cells
How macrophages deal with death
Hijacking multivesicular bodies enables long-term and exosome-mediated long-distance action of anthrax toxin
High-throughput screening identified selective inhibitors of exosome biogenesis and secretion : a drug repurposing strategy for advanced cancer
High-throughput functional genomics using CRISPR-Cas9
Heparan sulfate analogues regulate tumor-derived exosome formation that attenuates exosome functions in tumor processes
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
Gene editing, gene therapy, and cell xenotransplantation:cell transplantation across species
Extracellular vesicles and anti-cancer drug resistance
Extracellular vesicles : exosomes, microvesicles, and friends
Extracellular vesiclemediated EBAG9 transfer from cancer cells to tumor microenvironment promotes immune escape and tumor progression
Exosomes: key mediators of metastasis and pre-metastatic niche formation
Exosomes mediate drug resistance transfer in MCF-7 breast cancer cells and a probable mechanism is delivery of P-glycoprotein
Exosomes induce fibroblast differentiation into cancer-associated fibroblasts through TGFbeta signaling
Exosomes in the tumor microenvironment as mediators of cancer therapy resistance
Exosomes in Angiogenesis and Anti-angiogenic Therapy in Cancers
Exosomes from HNSCC promote angiogenesis through reprogramming of endothelial cells
Exosomes derived from gastric cancer cells activate NF-kappaB pathway in macrophages to promote cancer progression
Exosomes : dynamic mediators of extracellular communication in the tumor microenvironment
Exosomes : composition, biogenesis, and mechanisms in cancer metastasis and drug resistance
Exosomes : a new perspective in EGFR-mutated lung cancer
Exosome-derived microRNAs contribute to prostate cancer chemoresistance
Exosome secretion is enhanced by invadopodia and drives invasive behavior
Exosome purification and analysis using a facile microfluidic hydrodynamic trapping device
Exosome in tumour microenvironment : overview of the crosstalk between normal and cancer cells
Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology
Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
Exosomal PD-L1 : roles in tumor progression and immunotherapy
Evaluation and reduction of CRISPR off-target cleavage events
Epidermal growth factor/epidermal growth factor receptor signaling blockage inhibits tumor cell-derived exosome uptake by oral squamous cell carcinoma through macropinocytosis
Engineering adeno-associated viruses for clinical gene therapy
Drug repurposing: a promising tool to accelerate the drug discovery process
Drug repurposing : progress, challenges and recommendations
Dominant immunosuppression of dendritic cell function by prostate-cancer-derived exosomes
Curcumin reverses breast tumor exosomes mediated immune suppression of NK cell tumor cytotoxicity
Cortactin promotes exosome secretion by controlling branched actin dynamics
Combination cancer therapy with immune checkpoint blockade : mechanisms and strategies
Combination cancer therapies with immune checkpoint blockade : convergence on interferon signaling
Choosing the right tool for the job : RNAi, TALEN, or CRISPR
Ceramide triggers budding of exosome vesicles into multivesicular endosomes
Cellular disposal of miR23b by RAB27-dependent exosome release is linked to acquisition of metastatic properties
Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis
Cancer immunotherapy using checkpoint blockade
Cancer exosomes trigger fibroblast to myofibroblast differentiation
CRISPR-Cas9 for cancer therapy : opportunities and challenges
CD73 in small extracellular vesicles derived from HNSCC defines tumour-associated immunosuppression mediated by macrophages in the microenvironment
Breast cancer-derived exosomes regulate cell invasion and metastasis in breast cancer via miR-146a to activate cancer associated fibroblasts in tumor microenvironment
Biological properties of extracellular vesicles and their physiological functions
Biogenesis and function of ESCRT-dependent extracellular vesicles
Anticlogging hemofiltration device for mass collection of circulating tumor cells by ligand-free size selection
Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles
Adeno-associated virus(AAV)as a vector for gene therapy
Accelerated growth of B16BL6 tumor in mice through efficient uptake of their own exosomes by B16BL6 cells
ALIX-and ESCRT-III-dependent sorting of tetraspanins to exosomes
ALIX regulates tumor-mediated immunosuppression by controlling EGFR activity and PD-L1 presentation
ALIX binds a YPX(3)L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting
A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis
A framework for advancing our understanding of cancerassociated fibroblasts .
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Targeted inhibition of tumor-derived exosomes as a novel therapeutic option for cancer'
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