The optimized core peptide derived from CABIN1 efficiently inhibits calcineurin-mediated T-cell activation
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논문 Analysis
연구자 Analysis
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The optimized core peptide derived from CABIN1 efficiently inhibits calcineurin-mediated T-cell activation' 의 참고문헌
X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex
Transcriptional mechanisms underlying lymphocyte tolerance
Transcription factors of the NFAT family: regulation and function
Therapeutic potential of VIVIT, a selective peptide inhibitor of nuclear factor of activated T cells, in cardiovascular disorders
The eukaryotic proteome is shaped by E3 ubiquitin ligases targeting C-terminal degrons
T-cell receptor stimulation elicits an early phase of activation and a later phase of deactivation of the transcription factor NFAT1
Structure-based optimization of a peptidyl inhibitor against calcineurin-nuclear factor of activated T cell ( NFAT ) interaction
Structure of the calcineurin-NFAT complex: defining a T cell activation switch using solution NMR and crystal coordinates
Signal transmission between the plasmamembrane and nucleus of T-lymphocytes
STAR : ultrafast universal RNA-seq aligner .
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis
Quantitative mapping of protein-peptide affinity landscapes using spectrally encoded beads .
Phosphorylation of OGFOD1 by cell cycle-dependent kinase 7/9enhances the transcriptional activity of RNA polymerase II in breast cancer cells
Overexpression of C16orf74 is involved in aggressive pancreatic cancers
Open source clustering software
Ninjurin1 regulates lipopolysaccharideinduced inflammation through direct binding .
Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth
Neural functions of calcineurin in synaptic plasticity and memory
NINJ1 mediates plasma membrane rupture during lytic cell death
NFAT-specific inhibition by dNP2-VIVITAmeliorates autoimmune encephalomyelitisby regulation of Th1 and Th17
NFAT proteins : key regulators of T-cell development and function .
NFAT proteins : emerging roles in cancer progression
Models of T cell anergy : is there a common molecular mechanism?
KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals
JNK is involved in signal integration during costimulation of T lymphocytes
It takes two binding sites for calcineurin and NFAT to tango
Interaction of calcineurin with substrates and targeting proteins
Inhibition of the CD3-mediated calcium signal by protein kinase C activators in human T(Jurkat)lymphoblastoid cells
IkappaB kinases serve as a target of CD28 signaling
Expression of TGF-beta and fibrogenic genes in transplant recipients with tacrolimus and cyclosporine nephrotoxicity
Epithelial calcineurin controls microbiotadependent intestinal tumor development .
Dynamics of three-dimensional replication patterns during the S-phase, analysed by double labelling of DNA and confocal microscopy
DNA vaccine encoding chimeric protein encompassing epitopes of human ZP3 and ZP4 : immunogenicity and characterization of antibodies
Cyclin-dependent kinase 1 activity coordinates the chromatin associated state of Oct4 during cell cycle in embryonic stem cells
Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin
Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity
Cell permeable NFAT inhibitory peptide Sim-2-VIVIT inhibits T-cell activation and alleviates allergic airway inflammation and hyper-responsiveness
Calcineurin signaling and NFAT activation in cardiovascular and skeletal muscle development
Calcineurin inhibitors : 40 years later, can’t live without
Cabin 1 , a negative regulator for calcineurin signaling in T lymphocytes
Blockade of nuclear factor of activated T cells activation signaling suppresses balloon injury-induced neointima formation in a rat carotid artery model
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A
Activation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: regulation upon CD16 ligand binding
A role for the p38 MAP kinase pathway in the nuclear shuttling of NFATp
A new cell-permeable peptide allows successful allogeneic islet transplantation in mice
A new calcineurin inhibition domain in Cabin1
A guided tour into subcellular colocalization analysis in light microscopy
A cell-permeable NFAT inhibitor peptide prevents pressure-overload cardiac hypertrophy .
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The optimized core peptide derived from CABIN1 efficiently inhibits calcineurin-mediated T-cell activation'
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