Autophagy regulation by acetylation—implications for neurodegenerative diseases
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Autophagy regulation by acetylation—implications for neurodegenerative diseases' 의 참고문헌
microRNA-dependent modulation of histone acetylation in Waldenstrom macroglobulinemia
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
Tip60 HAT activity mediates APP induced lethality and apoptotic cell death in the CNS of a Drosophila Alzheimer’s disease model
Therapeutic targeting of autophagy in neurodegenerative and infectious diseases
The world of protein acetylation
The many roles of histone deacetylases in development and physiology : implications for disease and therapy
The many lives of KATs - detectors, integrators and modulators of the cellular environment
The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy
The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes
The growing landscape of lysine acetylation links metabolism and cell signalling
The genetic architecture of ALS
The emerging role of acetylation in the regulation of autophagy
The acetyl group buffering action of carnitine acetyltransferase offsets macronutrient-induced lysine acetylation of mitochondrial proteins
The ATG conjugation systems in autophagy
Suppression of aggregate formation of mutant huntingtin potentiates CREB-binding protein sequestration and apoptotic cell death
Structure, lipid scrambling activity and role in autophagosome formation of ATG9A
Small molecules enhance autophagy and reduce toxicity in Huntington’s disease models
Sirtuins as regulators of metabolism and healthspan
Sirtuins and their roles in brain aging and neurodegenerative disorders
Sirtuins : double players in Huntington’s disease
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson’s disease
Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease
Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
SIRT7 depletion inhibits cell proliferation and androgeninduced autophagy by suppressing the AR signaling in prostate cancer
SIRT5-mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer
SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy
SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis
SIRT1 protects against alpha-synuclein aggregation by activating molecular chaperones
SAHA induces caspase-independent, autophagic cell death of endometrial stromal sarcoma cells by influencing the mTOR pathway
Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington’s disease
Restoring Tip60 HAT/HDAC2 balance in the neurodegenerative brain relieves epigenetic transcriptional repression and reinstates cognition
Regulation of autophagy by the p300 acetyltransferase
Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer’s disease
Rapamycin pre-treatment protects against apoptosis
Proteome-wide acetylation dynamics in human cells
Protein N-terminal acetyltransferases:when the start matters
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy
Physical and functional HAT/HDAC interplay regulates protein acetylation balance
Phosphodiesterase type IV inhibition prevents sequestration of CREB binding protein, protects striatal parvalbumin interneurons and rescues motor deficits in the R6/2 mouse model of Huntington’s disease
Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells
Pcaf modulates polyglutamine pathology in a Drosophila model of Huntington’s disease
PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
P300/CBP-associated factor(PCAF)inhibits the growth of hepatocellular carcinoma by promoting cell autophagy
Novel targets for Huntington’s disease in an mTORindependent autophagy pathway
Neuroprotective role of Sirt1 in mammalian models of Huntington’s disease through activation of multiple Sirt1 targets
Mtor signaling in growth, metabolism, and disease
Mitochondrial protein acetylation is driven by acetylCoA from fatty acid oxidation
Mice knock out for the histone acetyltransferase p300/CREB binding protein-associated factor develop a resistance to amyloid toxicity
Mendelian neurodegenerative disease genes involved in autophagy
Mammalian macroautophagy at a glance
Mammalian autophagy : how does it work
Mammalian Sir2-related protein(SIRT)2-mediated modulation of resistance to axonal degeneration in slow Wallerian degeneration mice : a crucial role of tubulin deacetylation
Long-term memory deficits in Huntington’s disease are associated with reduced CBP histone acetylase activity
Leucine signals to mTORC1 via its metabolite acetylcoenzyme A
Leucine regulates autophagy via acetylation of the mTORC1component raptor
LC3B-II deacetylation by histone deacetylase 6 is involved in serum-starvation-induced autophagic degradation
Knockdown of transactive response DNA-binding protein(TDP-43)downregulates histone deacetylase 6
Isolation and characterization of autophagydefective mutants of Saccharomyces cerevisiae
International Review of Cell and Molecular Biology, Vol 316
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
Inhibition of histone deacetylase1 induces autophagy
Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model
Induction of Apoptosis and Autophagy in Breast Cancer Cells by a Novel HDAC8 Inhibitor
Increased SOD1 association with chromatin, DNA damage, p53 activation, and apoptosis in a cellular model of SOD1-linked ALS
Increase in HDAC9 suppresses myoblast differentiation via epigenetic regulation of autophagy in hypoxia
Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice
Histone deacetylase(HDAC)inhibitors attenuate cardiac hypertrophy by suppressing autophagy
Histone deacetylase HDAC4 promotes gastric cancer SGC7901 cells progression via p21 repression
Histone deacetylase 6 interacts with the microtubule-associated protein tau
Histone deacetylase 6 functions as a tumor suppressor by activating c-Jun NH2-terminal kinase-mediated beclin 1-dependent autophagic cell death in liver cancer
Histone deacetylase 10 promotes autophagy-mediated cell survival
Histone acetyltransferase p300 mediates histone acetylation of PS1 and BACE1 in a cellular model of Alzheimer’s disease
Histone acetylation in neuronal(dys)function
Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
HDAC6 regulates mutant SOD1 aggregation through two SMIR motifs and tubulin acetylation
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin
HDAC2 negatively regulates memory formation and synaptic plasticity
HDAC family members intertwined in the regulation of autophagy : a druggable vulnerability in aggressive tumor entities
HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis
Genomic investigation of alpha-synuclein multiplication and parkinsonism
Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy
Functions and mechanisms of nonhistone protein acetylation
Frontal cortex epigenetic dysregulation during the progression of Alzheimer’s disease
Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin
Effects of Longevinex(modified resveratrol)on cardioprotection and its mechanisms of action
Dysregulation of histone acetylation pathways in hippocampus and frontal cortex of Alzheimer’s disease patients
Dynamic association of the ULK1 complex with omegasomes during autophagy induction
Differential histone deacetylase mRNA expression patterns in amyotrophic lateral sclerosis
Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity
Deacetylation of nuclear LC3 drives autophagy initiation under starvation
Deacetylation of FoxO by Sirt1 plays an essential role in mediating starvation-induced autophagy in cardiac myocytes
Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity
Critical loss of CBP/p300 histone acetylase activity by caspase-6 during neurodegeneration
Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein
CREB-binding protein sequestration by expanded polyglutamine
CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer’s disease
Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3
Autophagy and neurodegeneration : pathogenic mechanisms and therapeutic opportunities
Autophagy : renovation of cells and tissues
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion
Assembly and interrogation of Alzheimer’s disease genetic networks reveal novel regulators of progression
ApoE4 and Abeta oligomers reduce BDNF expression via HDAC nuclear translocation
Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA
Amyloid-beta and Tau at the crossroads of Alzheimer’s disease
AlphaSynuclein is degraded by both autophagy and the proteasome
Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB
Acetylation targets mutant huntingtin to autophagosomes for degradation
Acetylated tau, a novel pathological signature in Alzheimer’s disease and other tauopathies
A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
A comprehensive glossary of autophagy-related molecules and processes(2nd edition)
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Autophagy regulation by acetylation—implications for neurodegenerative diseases'
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