Hepatocyte nuclear factor 4α and cancer-related cell signaling pathways: a promising insight into cancer treatment
활용도 Analysis
논문 Analysis
연구자 Analysis
저자
Lv Duo-Duo
Zhou Ling-Yun
Tang Hong
제어번호
107245201
학술지명
Experimental and molecular medicine
권호사항
Vol.
53
No.
-
[
2021
]
발행처
생화학분자생물학회
자료유형
학술저널
수록면
1-11
언어
English
출판년도
2021
등재정보
KCI등재
판매처
'
Hepatocyte nuclear factor 4α and cancer-related cell signaling pathways: a promising insight into cancer treatment' 의 참고문헌
miR-34a inhibits proliferation, migration and invasion of paediatric neuroblastoma cells via targeting HNF4alpha
VHL deficiency augments anthracycline sensitivity of clear cell renal cell carcinomas by down-regulating ALDH2
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
The transcription factor encyclopedia
The stable repression of mesenchymal program is required for hepatocyte identity : a novel role for hepatocyte nuclear factor 4alpha
The role of hepatocyte nuclear factor 4alpha in metastatic tumor formation of hepatocellular carcinoma and its close relationship with the mesenchymal-epithelial transition markers
The expression of hepatocyte nuclear factor-4alpha, a developmental regulator of visceral endoderm, correlates with the intestinal phenotype of gastric adenocarcinomas
The complexity of NF-kappaB signaling in inflammation and cancer
Tg737 regulates epithelial-mesenchymal transition and cancer stem cell properties via a negative feedback circuit between Snail and HNF4alpha during liver stem cell malignant transformation
TGFbeta overrides HNF4alpha tumor suppressing activity through GSK3beta inactivation : implication for hepatocellular carcinoma gene therapy
Src tyrosine kinase phosphorylation of nuclear receptor HNF4alpha correlates with isoform-specific loss of HNF4alpha in human colon cancer
Snail controls differentiation of hepatocytes by repressing HNF4alpha expression
Signal transducer and activator of transcription(STATs)proteins in cancer and inflammation : functions and therapeutic implication
STAT1 and STAT3 in tumorigenesis : a matter of balance
STAT signaling in mammary gland differentiation, cell survival and tumorigenesis
Roles of E-cadherin and Noncoding RNAs in the Epithelial–mesenchymal Transition and Progression in Gastric Cancer
Role of hepatocyte nuclear factor 4alpha(HNF4alpha)in cell proliferation and cancer
Role of hepatocyte nuclear factor 4 alpha in cell proliferation and gemcitabine resistance in pancreatic adenocarcinoma
Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor-mediated cell growth In vitro
Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development
ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity
P1 promoter-driven HNF4α isoforms are specifically repressed by β-catenin signaling in colorectal cancer cells
Overexpression of hepatocyte nuclear factor 4alpha in human mesenchymal stem cells suppresses hepatocellular carcinoma development through Wnt/beta-catenin signaling pathway downregulation
Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression
Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer
Nitric oxide and TGF-beta1 inhibit HNF-4alpha function in HEPG2 cells
New Tools for Molecular Therapy of Hepatocellular Carcinoma
Mutual amplification of HNF4alpha and IL-1R1 composes an inflammatory circuit in Helicobacter pylori associated gastric carcinogenesis
Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young(MODY1)
Mutant IDH inhibits HNF-4alpha to block hepatocyte differentiation and promote biliary cancer
Molecular basis of Barrett’s oesophagus and oesophageal adenocarcinoma
Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha
Long non-coding RNA SNHG16 regulates cell behaviors through miR-542-3p/HNF4α axis via RAS/RAF/MEK/ERK signaling pathway in pediatric neuroblastoma cells
Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily
Involvement of miRNA-29a in epigenetic regulation of transforming growth factor-beta-induced epithelial-mesenchymal transition in hepatocellular carcinoma
Inhibition of colorectal cancer by targeting hepatocyte nuclear factor-4alpha
Inhibition of Aurora-A kinase induces cell cycle arrest in epithelial ovarian cancer stem cells by affecting NFkB pathway
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
Increased protein expression of DNA methyltransferase(DNMT)1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas
Identification of potential transcription factors, long noncoding RNAs, and microRNAs associated with hepatocellular carcinoma
Identification of potential biomarkers for measuring inhibition of Src kinase activity in colon cancer cells following treatment with dasatinib
Identification of an endogenous ligand bound to a native orphan nuclear receptor
Human renal cell carcinogenesis is accompanied by a coordinate loss of the tissue specific transcription factors HNF4 alpha and HNF1 alpha
Hnf4alpha is a key gene that can generate columnar metaplasia in oesophageal epithelium
Hepatocyte nuclear factor 4alpha-nuclear factor-kappaB feedback circuit modulates liver cancer progression
Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium
Hepatocyte nuclear factor 4alpha(nuclear receptor 2A1)is essential for maintenance of hepatic gene expression and lipid homeostasis
Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver
Hepatocyte nuclear factor 4alpha is required for cell differentiation and homeostasis in the adult mouse gastric epithelium
Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon
Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis
Hepatocyte nuclear factor 4alpha contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation
Hepatocyte nuclear factor 4-alpha involvement in liver and intestinal inflammatory networks
Hepatocyte nuclear factor 4 alpha suppresses the development of hepatocellular carcinoma
Hepatocyte nuclear factor 4 alpha promotes the invasion, metastasis and angiogenesis of neuroblastoma cells via targeting matrix metalloproteinase 14
Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents
HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer
HNF4alpha: a new biomarker in colon cancer?
HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma
HNF4alpha is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer
HNF4alpha induced chemosensitivity to oxaliplatin and 5-FU mediated by OCT1 and CNT3 in renal cell carcinoma
HNF4alpha downregulation promotes tumor migration and invasion by regulating Ecadherin in renal cell carcinoma
HNF4alpha as a marker for invasive mucinous adenocarcinoma of the lung
HNF4A immunohistochemistry facilitates distinction between primary and metastatic breast and gastric carcinoma
HNF-4alpha promotes multidrug resistance of gastric cancer cells through the modulation of cell apoptosis
Galpha12 overexpressed in hepatocellular carcinoma reduces microRNA-122 expression via HNF4alpha inactivation, which causes c-Met induction
Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo : HNF-4 is a marker for primary endoderm in the implanting blastocyst
Expression of hepatocyte nuclear factor 4 alpha in primary ovarian mucinous tumors
Expression of HNF4alpha isoforms in mouse liver development is regulated by sequential promoter usage and constitutive 3’ end splicing
Expression and localization of P1 promoter-driven hepatocyte nuclear factor-4alpha(HNF4alpha)isoforms in human and rats
Epithelialmesenchymal transitions in development and disease
Epithelial-mesenchymal transitions in development and disease : old views and new perspectives
Epigenetic regulation of MicroRNA-122 by peroxisome proliferator activated receptor-gamma and hepatitis b virus X protein in hepatocellular carcinoma cells
Epigenetic control of HNF-4alpha in colon carcinoma cells affects MUC4 expression and malignancy
Epigenetic control of EMT/MET dynamics : HNF4alpha impacts DNMT3s through miRs-29
Epigenetic Reprogramming of TGF-β Signaling in Breast Cancer
Dysregulated expression of P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha in the pathogenesis of human cancer
Dual delivery of HNF4alpha and cisplatin by mesoporous silica nanoparticles inhibits cancer pluripotency and tumorigenicity in hepatomaderived CD133-expressing stem cells
Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos
Differentiation therapy of hepatocellular carcinoma in mice with recombinant adenovirus carrying hepatocyte nuclear factor-4alpha gene
Differential effects, on oncogenic pathway signalling, by derivatives of the HNF4 alpha inhibitor BI6015
Differential effects of hepatocyte nuclear factor 4alpha isoforms on tumor growth and t-cell factor 4/AP-1 interactions in human colorectal Cancer cells
Developmental and tissuespecific regulation of hepatocyte nuclear factor 4-alpha(HNF4-alpha)isoforms in rodents
Deregulation of hepatocyte nuclear factor 4(HNF4)as a marker of epithelial tumors progression
Deciphering the developmental dynamics of the mouse liver transcriptome
Curcumin inhibits LPS-induced EMT through downregulation of NF-kappaB-Snail signaling in breast cancer cells
Crosstalk of HNF4alpha with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipids
Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis
Cervical neonatal neuroblastoma with recurrent SVT
Cell signaling and cancer: a mechanistic insight into drug resistance
Berberine attenuated proliferation, invasion and migration by targeting the AMPK/HNF4alpha/WNT5A pathway in gastric carcinoma
Apoptosis signal-regulating kinase 1 mediates the inhibitory effect of hepatocyte nuclear factor-4alpha on hepatocellular carcinoma
Apicidin sensitizes pancreatic cancer cells to gemcitabine by epigenetically regulating MUC4 expression
An HNF4alpha-microRNA-194/192 signaling axis maintains hepatic cell function
An HNF4alpha-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis
Activation of NF-kappaB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-tomesenchymal transition in mammary tumor cell lines
A systematic analysis of the 3’UTR of HNF4A mRNA reveals an interplay of regulatory elements including miRNA target sites
A subpopulation of airway epithelial cells that express hepatocyte nuclear factor 4alpha-its implication in the development of non-terminal respiratory unit-type lung adenocarcinoma
A double-negative feedback loop between Wnt-beta-catenin signaling and HNF4alpha regulates epithelial-mesenchymal transition in hepatocellular carcinoma
A comprehensive DNA methylation profile of epithelialto-mesenchymal transition
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Hepatocyte nuclear factor 4α and cancer-related cell signaling pathways: a promising insight into cancer treatment'
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