Pathogenic diversity of RNA variants and RNA variation-associated factors in cancer development
활용도 Analysis
논문 Analysis
연구자 Analysis
저자
양희두
남석우
제어번호
107230713
학술지명
Experimental and molecular medicine
권호사항
Vol.
52
No.
-
[
2020
]
발행처
생화학분자생물학회
자료유형
학술저널
수록면
1-12
언어
English
출판년도
2020
등재정보
KCI등재
판매처
'
Pathogenic diversity of RNA variants and RNA variation-associated factors in cancer development' 의 참고문헌
m(6)A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade
m(6)A demethylase ALKBH5 maintains tumorigenicity of glioblastoma stem-like cells by sustaining FOXM1 expression and cell proliferation program
m(6)A RNA methylation regulates the self-renewal and tumorigenesis of glioblastoma stem cells
m(6)A RNA methylation promotes XIST-mediated transcriptional repression
Zcchc11-dependent uridylation of microRNA directs cytokine expression
Widespread shortening of 3’UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia
Widespread intronic polyadenylation diversifies immune cell transcriptomes
Using positional distribution to identify splicing elements and predict pre-mRNA processing defects in human genes
Two novel heparin-binding vascular endothelial growth factor splices, L-VEGF144 and L-VEGF138, are expressed in human glioblastoma cells
Transient overexpression of exogenous APOBEC3A causes C-to-U RNA editing of thousands of genes
Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA-editing targets in transcript 3’ UTRs
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation
The non-canonical poly(A)polymerase FAM46C acts as an onco-suppressor in multiple myeloma
The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis
The m(6)A methyltransferase METTL3 promotes translation in human cancer cells
The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo
The genomic landscape and clinical relevance of A-to-I RNA editing in human cancers
The U6 snRNA m(6)A methyltransferase METTL16regulates SAM synthetase intron retention
The APOBEC Protein Family : United by Structure, Divergent in Function
Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers
Synonymous mutations frequently act as driver mutations in human cancers
Structural differences between Pri-miRNA paralogs promote alternative drosha cleavage and expand target repertoires
Structural basis for cooperative function of Mettl3 and Mettl14 methyltransferases
Stress-response protein RBM3 attenuates the stem-like properties of prostate cancer cells by interfering with CD44 variant splicing
SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts
Regulation of microRNA function in animals
Regulation of co-transcriptional pre-mRNA splicing by m(6)A through the low-complexity protein hnRNPG
Regulation of alternative splicing by histone modifications
Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis
Redirection of silencing targets by adenosine-to-inosine editing of miRNAs
Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma
RNA editing of SLC22A3 drives early tumor invasion and metastasis in familial esophageal cancer
RNA editing in the human ENCODE RNA-seq data
RNA editing in the forefront of epitranscriptomics and human health
RNA editing in pathogenesis of cancer
RNA editing in RHOQ promotes invasion potential in colorectal cancer
RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2
QuagmiR : a cloud-based application for isomiR big data analytics
Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing
Promoter usage and alternative splicing
Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites
Post-transcriptional gene regulation by mRNA modifications
Post-transcriptional control of miRNA biogenesis
Pharmacology of modulators of alternative splicing
Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5’ sites
Noisy splicing drives mRNA isoform diversity in human cells
NUDT21 negatively regulates PSMB2 and CXXC5 by alternative polyadenylation and contributes to hepatocellular carcinoma suppression
N6-methyladenosine links RNA metabolism to cancer progression
N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions
Molecular cloning of an apolipoprotein B messenger RNA editing protein
Molecular basis for the single-nucleotide precision of primary microRNA processing
Modulation of microRNA processing and expression through RNA editing by ADAR deaminases
Modulation of microRNA editing, expression and processing by ADAR2 deaminase in glioblastoma
Mechanisms and regulation of alternative Pre-mRNA splicing
MTHFD2 links RNA methylation to metabolic reprogramming in renal cell carcinoma
METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N(6)-methyladenosine-dependent primary MicroRNA processing
IsomiRs: Expanding the miRNA repression toolbox beyond the seed
Intron retention is a widespread mechanism of tumorsuppressor inactivation
Identification of Wilms’ tumor 1-associating protein complex and its role in alternative splicing and the cell cycle
Identification and characterization of an alternative cancer-derived PD-L1 splice variant
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m(6)A-demethylation of NANOG mRNA
HNRNPA2B1 Is a mediator of m(6)A-dependent nuclear RNA processing events
Genome-wide mapping of DROSHA cleavage sites on primary MicroRNAs and noncanonical substrates
Gene expression regulation mediated through reversible m(6)A RNA methylation
Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis
Frequent pathway mutations of splicing machinery in myelodysplasia
FTO plays an oncogenic role in acute myeloid leukemia as a N(6)-methyladenosine RNA demethylase
Epigenetic plasticity and the hallmarks of cancer
Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3’-UTR landscape across seven tumour types
Diversifying microRNA sequence and function
Dicer partner protein tunes the length of miRNAs using base-mismatch in the pre-miRNA stem
Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome
Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients
Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage
Bioinformatic identification of candidate cis-regulatory elements involved in human mRNA polyadenylation
Beyond the onelocus-one-miRNA paradigm: microRNA isoforms enable deeper insights into breast cancer heterogeneity
Barrier to autointegration factor 1, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3, and splicing factor 3b subunit 4 as early-stage cancer decision markers and drivers of hepatocellular carcinoma
Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells
An integrated encyclopedia of DNA elements in the human genome
Alternative polyadenylation of mRNA precursors
Alternative isoform regulation in human tissue transcriptomes
Alternative 3′ UTRs act as scaffolds to regulate membrane protein localization
Altered RNA processing in cancer pathogenesis and therapy
Altered RNA editing in 3’ UTR perturbs microRNA-mediated regulation of oncogenes and tumorsuppressors
Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis
APOBEC enzymes : mutagenic fuel for cancer evolution and heterogeneity
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility
ADAR1 overexpression is associated with cervical cancer progression and angiogenesis
ADAR1 activation drives leukemia stem cell self-renewal by impairing Let-7 biogenesis
ADAR-mediated RNA editing predicts progression and prognosis of gastric cancer
A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes
A-to-I RNA editing contributes to proteomic diversity in cancer
A novel Bcl-x splice product, Bcl-xAK, triggers apoptosis in human melanoma cells without BH3 domain
A mammalian RNA editing enzyme
A large-scale analysis of mRNA polyadenylation of human and mouse genes
A developmentally regulated activity that unwinds RNA duplexes
A METTL3-METTL14complex mediates mammalian nuclear RNA N6-adenosine methylation
5’ isomiR variation is of functional and evolutionary importance
3’ UTR shortening represses tumor-suppressor genes in trans by disrupting ceRNA crosstalk
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Pathogenic diversity of RNA variants and RNA variation-associated factors in cancer development'
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