Pro-apoptotic peptides-based cancer therapies: challenges and strategies to enhance therapeutic efficacy
활용도 Analysis
논문 Analysis
연구자 Analysis
저자
민경아
푸자
함송희
신명철
제어번호
106036344
학술지명
Archives of Pharmacal Research
권호사항
Vol.
41
No.
6
[
2018
]
발행처
대한약학회
발행처 URL
http://www.psk.or.kr
자료유형
학술저널
수록면
594-616
(
23쪽)
언어
English
출판년도
2018
등재정보
KCI등재
소장기관
부산대학교 중앙도서관
숙명여자대학교 중앙도서관
영남대학교 중앙도서관
영남대학교 중앙도서관
중앙대학교 서울캠퍼스 중앙도서관
중앙대학교 서울캠퍼스 중앙도서관
중앙대학교 서울캠퍼스 중앙도서관
판매처
'
Pro-apoptotic peptides-based cancer therapies: challenges and strategies to enhance therapeutic efficacy' 의 참고문헌
pH-sensitive polymeric micelles for the Co-delivery of proapoptotic peptide and anticancer drug for synergistic cancer therapy
p53, the cellular gatekeeper for growth and division
p53 mutations in human cancers
iRGD-targeted delivery of a pro-apoptotic peptide activated by cathepsin B inhibits tumor growth and metastasis in mice
When the guardian sleeps: reactivation of the p53 pathway in cancer
Vascular-specific growth factors and blood vessel formation
Vascular changes in tumors resistant to a vascular disrupting nanoparticle treatment
VDAC1-based peptides: novel pro-apoptotic agents and potential therapeutics for B-cell chronic lymphocytic leukemia
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex
Tuning the anticancer activity of a novel pro-apoptotic peptide using gold nanoparticle platforms
Tumor-penetrating nanosystem strongly suppresses breast tumor growth
Tumor-penetrating iRGD peptide inhibits metastasis
Tumor vasculature targeting through NGR peptide-based drug delivery systems
Tumor targeting with RGD peptide ligands-design of new molecular conjugates for imaging and therapy of cancers
Tumor penetrating peptides for improved drug delivery
Tumor delivery of macromolecular drugs based on the EPR effect
Transtumoral targeting enabled by a novel neuropilin-binding peptide
Thermo- and pH-responsive polymers in drug delivery
Therapeutic platforms based on gold nanoparticles and their covalent conjugates with drug molecules
The transferrin receptor and the targeted delivery of therapeutic agents against cancer
The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability
The role of autophagy in cancer: therapeutic implications
The cell death-inducing activity of the peptide containing Noxa mitochondrial-targeting domain is associated with calcium release
The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
The CNGRC-GG-D (KLAKLAK) 2 peptide induces a caspase-independent, Ca2 + -dependent death in human leukemic myeloid cells by targeting surface aminopeptidase N/CD13
The Bcl-2 protein family: arbiters of cell survival
The BCL-2 protein family: opposing activities that mediate cell death
Targeting tumor suppressor p53 for cancer therapy: strategies, challenges and opportunities
Targeting of p32 in peritoneal carcinomatosis with intraperitoneal linTT1 peptide-guided pro-apoptotic nanoparticles
Targeting of drugs and nanoparticles to tumors
Targeting acute myeloid leukemia with a proapoptotic peptide conjugated to a Toll-like receptor 2-mediated cell-penetrating peptide
Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer
Targeting AKT with the proapoptotic peptide, TAT-CTMP: a novel strategy for the treatment of human pancreatic adenocarcinoma
Targeted proapoptotic LHRH-BH3 peptide
Targeted oncolytic peptide for treatment of ovarian cancers
Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma
Targeted drug delivery via the folate receptor
Targeted delivery of proapoptotic peptides to tumor-associated macrophages improves survival
Targeted delivery of a proapoptotic peptide to tumors in vivo
Targeted delivery of IFNgamma to tumor vessels uncouples antitumor from counterregulatory mechanisms
Tandem-multimeric F3-gelonin fusion toxins for enhanced anti-cancer activity for prostate cancer treatment
TRAIL-NP hybrids for cancer therapy: a review
TNF-R1 signaling: a beautiful pathway
Systemic delivery of tumor-targeted bax-derived membrane-active peptides for the treatment of melanoma tumors in a humanized SCID mouse model
Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma
Synthetic therapeutic peptides: science and market
Synthetic constrained peptide selectively binds and antagonizes death receptor 5
Synthesis and evaluation of multivalent M2pep peptides for targeting alternatively activated M2 macrophages
Suppression of tumor growth and metastasis by a VEGFR-1 antagonizing peptide identified from a phage display library
Structure-based design of an agonistic peptide targeting Fas
Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif
Stimuli-responsive polymers: biomedical applications and challenges for clinical translation
Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems
Smac therapeutic Peptide nanoparticles inducing apoptosis of cancer cells for combination chemotherapy with Doxorubicin
Signal transduction via platelet-derived growth factor receptors
Self-assembling peptide-based building blocks in medical applications
Role of NF-kappaB and Akt/PI3 K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death
Review of Epidermal Growth Factor Receptor Biology
Recent advances in self-assembled peptides: Implications for targeted drug delivery and vaccine engineering
RGD peptides induce apoptosis by direct caspase-3 activation
Preparation and characterization of gelonin-melittin fusion biotoxin for synergistically enhanced anti-tumor activity
Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: therapeutic effect of a novel polyarginine-conjugated Smac peptide
Polymeric nanoparticles for targeted treatment in oncology: current insights
Photochemical internalization provides time-and space-controlled endolysosomal escape of therapeutic molecules
Photochemical internalization (PCI) in cancer therapy: from bench towards bedside medicine
Peptides which bind to E-selectin and block neutrophil adhesion
Peptide-based cancer therapy: opportunity and challenge
Peptide ligand-modified nanomedicines for targeting cells at the tumor microenvironment
Peptide and protein drug delivery to and into tumors: challenges and solutions
Passive and active drug targeting: drug delivery to tumors as an example
Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)
Origin of anti-tumor activity of the cysteine-containing GO peptides and further optimization of their cytotoxic properties
Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels
Novel polymeric nanoparticles for intracellular delivery of peptide Cargos: antitumor efficacy of the BCL-2 conversion peptide NuBCP-9
Novel LHRH-receptor-targeted cytolytic peptide, EP-100: first-in-human phase I study in patients with advanced LHRH-receptor-expressing solid tumors
Neuropilin-1 is a receptor for transforming growth factor beta-1, activates its latent form, and promotes regulatory T cell activity
Neuropilin is a semaphorin III receptor
Necrosis: a specific form of programmed cell death?
Nanoparticles for combination drug therapy
Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date
Multivalent targeting based delivery of therapeutic peptide using AP1-ELP carrier for effective cancer therapy
Multivalent polymers displaying M2 macrophage-targeting peptides improve target binding avidity and serum stability
Multivalent display of pendant pro-apoptotic peptides increases cytotoxic activity
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
Multifunctional theranostic gold nanoparticles for targeted CT imaging and photothermal therapy
Multifunctional superparamagnetic iron oxide nanoparticles for combined chemotherapy and hyperthermia cancer treatment
Multifunctional enveloped mesoporous silica nanoparticles for subcellular co-delivery of drug and therapeutic peptide
Multifunctional envelope-type mesoporous silica nanoparticles for tumor-triggered targeting drug delivery
Molecular tumor targeting of gelonin by fusion with F3 peptide
Mode of action of membrane active antimicrobial peptides
Mitochondrial targeted peptides for cancer therapy
Mitochondrial apoptosis and BH3 mimetics
Mitochondria and cell death: outer membrane permeabilization and beyond
Mitochondria and apoptosis
Mesoporous silica nanoparticles for intracellular delivery of membrane-impermeable proteins
Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers
Membrane structure and fusion-triggering conformational change of the fusion domain from influenza hemagglutinin
Membrane fusion by peptide analogues of influenza virus haemagglutinin
Melittin: a membrane-active peptide with diverse functions
Mechanistic validation of a clinical lead stapled peptide that reactivates p53 by dual HDM2 and HDMX targeting
Magnetic iron oxide nanoparticles: Recent trends in design and synthesis of magnetoresponsive nanosystems
Light induced drug delivery into cancer cells
Ligand-targeted therapeutics in anticancer therapy
Ligand-directed active tumor-targeting polymeric nanoparticles for cancer chemotherapy
Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells
Iron oxide based nanoparticles for multimodal imaging and magnetoresponsive therapy
Intracellular delivery of a proapoptotic peptide via conjugation to a RAFT synthesized endosomolytic polymer
Intracellular Targeting of the Oncogenic MUC1-C Protein with a Novel GO-203 Nanoparticle Formulation
Integrins in cancer: biological implications and therapeutic opportunities
Insulin and insulin-like growth factor signalling in neoplasia
Inhibition of established micrometastases by targeted drug delivery via cell surface-associated GRP78
Inhibiting the inhibitors: retro-inverso Smac peptides
Induction of cancer cell death by self-assembling nanostructures incorporating a cytotoxic peptide
Induction of Ca(2) + -driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction
Improving the endosomal escape of cell-penetrating peptides and their cargos: strategies and challenges
Identification of a peptide blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis
Identification of a novel peptide ligand of human transfrrin receptor 1 for targeted tumor delivery drug
Hypothalamic hormones and cancer
H + -induced membrane insertion of influenza virus hemagglutinin involves the HA2 amino-terminal fusion peptide but not the coiled coil region
GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery
Functionalized gold nanoparticles: synthesis, properties and applications-a review
From antimicrobial to anticancer peptides. A review
Evolving strategies for tumor immunotherapy: enhancing the enhancer and suppressing the suppressor
Enzyme-cleavable polymeric micelles for the intracellular delivery of proapoptotic peptides
Enhancing endosomal escape for intracellular delivery of macromolecular biologic therapeutics
Enhancement of the antiangiogenic activity of interleukin-12 by peptide targeted delivery of the cytokine to alphavbeta3 integrin
Enhanced in vivo antitumor efficacy of dual-functional peptide-modified docetaxel nanoparticles through tumor targeting and Hsp90 inhibition
Enhanced antitumor effects of the BRBP1 compound peptide BRBP1-TAT-KLA on human brain metastatic breast cancer
Endothelial cells of tumor vessels: abnormal but not absent
Efficient identification of murine M2 macrophage peptide targeting ligands by phage display and next-generation sequencing
EGFR and cancer prognosis
Dual-targeting pro-apoptotic peptide for programmed cancer cell death via specific mitochondria damage
Drugs acting on homeostasis: challenging cancer cell adaptation
Directly targeting the mitochondrial pathway of apoptosis for cancer therapy using BH3 mimetics-recent successes, current challenges and future promise
Designed BH3 peptides with high affinity and specificity for targeting Mcl-1 in cells
Design and application of antimicrobial peptide conjugates
Delivery of intracellular-acting biologics in pro-apoptotic therapies
Degradable controlled-release polymers and polymeric nanoparticles: mechanisms of controlling drug release
De novo design of a tumor-penetrating peptide
De novo antimicrobial peptides with low mammalian cell toxicity
Current scenario of peptide-based drugs: the key roles of cationic antitumor and antiviral peptides
Core-shell nanoparticle-based peptide therapeutics and combined hyperthermia for enhanced cancer cell apoptosis
Construction and expression of sTRAIL-melittin combining enhanced anticancer activity with antibacterial activity in Escherichia coli
Conformational and molecular basis for induction of apoptosis by a p53 C-terminal peptide in human cancer cells
Clinical translation of angiogenesis inhibitors
Cleavage by caspase 8 and mitochondrial membrane association activate the BH3-only protein Bid during TRAIL-induced apoptosis
Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas
Cellular uptake of the tat protein from human immunodeficiency virus
Cellular abnormalities of blood vessels as targets in cancer
Cell-penetrating peptides: achievements and challenges in application for cancer treatment
Cell-penetrating peptides: 20 years later, where do we stand?
Cell-penetrating apoptotic peptide/p53 DNA nanocomplex as adjuvant therapy for drug-resistant breast cancer
Cell death regulation by the mammalian IAP antagonist Diablo/Smac
Cancer theranostics: the rise of targeted magnetic nanoparticles
Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology
Cancer nanomedicine: from targeted delivery to combination therapy
Cancer drug resistance: an evolving paradigm
Bladder tumor-targeted delivery of pro-apoptotic peptide for cancer therapy
Biologic and therapeutic role of HER2 in cancer
BH3 mimetics: status of the field and new developments
Autophagy: renovation of cells and tissues
Aptamer-conjugated nanomaterials and their applications
Application of membrane-active peptides for drug and gene delivery across cellular membranes
Apoptosis: a review of programmed cell death
Apoptosis-the p53 network
Apoptosis and clearance of apoptotic cells
Apoptosis and autophagy: regulatory connections between two supposedly different processes
Antibody-drug conjugates: an emerging concept in cancer therapy
Anti-cancer activity of targeted proapoptotic peptides
Anti-apoptosis and cell survival: a review
An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability
Amphipathic tail-anchoring peptide and Bcl-2 homology domain-3 (BH3) peptides from Bcl-2 family proteins induce apoptosis through different mechanisms
Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis
A tumorhoming peptide with a targeting specificity related to lymphatic vessels
A structural view of mitochondria-mediated apoptosis
A specific cell-penetrating peptide induces apoptosis in SKOV3 cells by down-regulation of Bcl-2
A review of current nanoparticle and targeting moieties for the delivery of cancer therapeutics
A novel transferrin receptor-targeted hybrid peptide disintegrates cancer cell membrane to induce rapid killing of cancer cells
A novel peptide isolated from a phage display library inhibits tumor growth and metastasis by blocking the binding of vascular endothelial growth factor to its kinase domain receptor
A novel hybrid peptide targeting EGFR-expressing cancers
A new anti-cancer strategy of damaging mitochondria by pro-apoptotic peptide functionalized gold nanoparticles
A dimethylmaleic acid-melittin-polylysine conjugate with reduced toxicity, pH-triggered endosomolytic activity and enhanced gene transfer potential
A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells
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Pro-apoptotic peptides-based cancer therapies: challenges and strategies to enhance therapeutic efficacy'
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