Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity

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' Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity' 의 참고문헌

  • The impact of pharmacogenomics research on drug development
    Liou SY [2012]
  • TRPV1 antagonistic analgesic effect: a randomized study of AZD1386 in pain after third molar extraction
    Quiding H [2013]
  • Precision medicine in oncology drug development: a pharma perspective
  • Population differences in major functional polymorphisms of pharmacokinetics/pharmacodynamics-related genes in Eastern Asians and Europeans: implications in the clinical trials for novel drug development
    Kurose K [2012]
  • Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology
  • Pharmacogenomics in clinical practice and drug development
    Harper AR [2012]
  • Pharmacogenetics and drug development: the path to safer and more effective drugs
    Roses AD [2004]
  • Oral and cutaneous thermosensory pro- file of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial
  • Multi-omics and metabolic modelling pipelines: challenges and tools for systems microbiology
    Fondi M [2015]
  • Metabolomics in drug discovery and development
  • Korean, Japanese, and Chinese populations featured similar genes encoding drug-metabolizing enzymes and transporters: a DMET Plus microarray assessment
    Yi S [2014]
  • Integrated multi-omics analysis of oligodendroglial tumours identifies three subgroups of 1p/19q co-deleted gliomas
    Kamoun A [2016]
  • Identification of omega- or (omega-1)-hydroxylated medium-chain acylcarnitines as novel urinary biomarkers for CYP3A activity
    Kim B [2018]
  • Glutathione S-transferases: a review
    Salinas AE [1999]
  • GST M1-T1 null allele frequency patterns in geographically assorted human populations: a phylogenetic approach
  • Evaluation of endogenous metabolic markers of hepatic CYP3A activity using metabolic profiling and midazolam clearance
    Shin KH [2013]
  • Emerging applications of metabolomics in drug discovery and precision medicine
    Wishart DS [2016]
  • Diagnosing the decline in pharmaceutical R&D efficiency
    Scannell JW [2012]
  • Concordance of DMET plus genotyping results with those of orthogonal genotyping methods
  • Biomarker enrichment strategies: matching trial design to biomarker credentials
    Freidlin B [2014]
  • Assessing the utility of whole genome amplified DNA as a template for DMET Plus array
    He YJ [2012]
  • A new population-enrichment strategy to improve efficiency of placebo-controlled clinical trials of antidepressant drugs
  • A collaborative approach to develop a multi-omics data analytics platform for translational research