Regulation of Osteoblast Metabolism by Wnt Signaling
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Regulation of Osteoblast Metabolism by Wnt Signaling' 의 참고문헌
Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway
XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation
Wntless functions in mature osteoblasts to regulate bone mass
Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation
Wnt3a regulates mitochondrial biogenesis through p38/CREB pathway
Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis
Wnt/<TEX>$\beta$</TEX>-catenin signaling and disease
Wnt-Lrp5 signaling regulates fatty acid metabolism in the osteoblast
Wnt-Frizzled/planar cell polarity signaling: cellular orientation by facing the wind (Wnt)
Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation
Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity
Wnt-3a regulates somite and tailbud formation in the mouse embryo
Wnt signaling through inhibition of <TEX>$\beta$</TEX>-catenin degradation in an intact Axin1 complex
Wnt signaling regulates mitochondrial physiology and insulin sensitivity
Wnt protein signaling reduces nuclear acetyl-coa levels to suppress gene expression during osteoblast differentiation
Wnt gene expression in the post-natal growth plate: regulation with chondrocyte differentiation
Wnt and calcium signaling: beta-catenin-independent pathways
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
WNT11 acts as a directional cue to organize the elongation of early muscle fibres
WNT10B mutations in human obesity
WNT1 mutations in early-onset osteoporosis and osteogenesis imperfecta
WNT-LRP5 signaling induces Warburg effect through mTORC2 activation during osteoblast differentiation
Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
Uptake of postprandial lipoproteins into bone in vivo: impact on osteoblast function
Up-regulation of glycolytic metabolism is required for <TEX>$HIF1{\alpha}$</TEX>-driven bone formation
Understanding the Warburg effect: the metabolic requirements of cell proliferation
The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression
The sequence and gene characterization of a 400-kb candidate region for IDDM4 on chromosome 11q13
The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates
The effects of ovarian hormones on glucose and fatty acid oxidation during exercise in female ovariectomized rats
The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation
The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors
The Wnt signaling pathway effector TCF7L2 is upregulated by insulin and represses hepatic gluconeogenesis
The WNT signalling pathway and diabetes mellitus
TSC2 mediates cellular energy response to control cell growth and survival
TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program
TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis
Structure-based mutation analysis shows the importance of LRP5 beta-propeller 1 in modulating Dkk1-mediated inhibition of Wnt signaling
Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density
Severe hypercholesterolemia, impaired fat tolerance, and advanced atherosclerosis in mice lacking both low density lipoprotein receptor-related protein 5 and apolipoprotein E
Selective disruption of Tcf7l2 in the pancreatic <TEX>$\beta$</TEX> cell impairs secretory function and lowers <TEX>$\beta$</TEX> cell mass
Rictor is required for optimal bone accrual in response to anti-sclerostin therapy in the mouse
Regulation of TCF3 by Wnt-dependent phosphorylation during vertebrate axis specification
Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling
Proximal events in Wnt signal transduction
Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner
Polymorphisms of the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study
Planar cell polarity in vertebrate limb morphogenesis
Parathyroid hormone signaling through low-density lipoprotein-related protein 6
Parathyroid hormone receptor directly interacts with dishevelled to regulate beta-catenin signaling and osteoclastogenesis
Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis
Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish
Modulation of embryonic intracellular Ca2+ signaling by Wnt-5A
Missense polymorphisms of the WNT16 gene are associated with bone mass, hip geometry and fractures
Metabolic studies of bone in vitro. II. The metabolic patterns of accretion and resorption
Metabolic studies of bone in vitro. I. Normal bone
Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
Low-density lipoprotein receptor-related protein 5 variant Q89R is associated with hypertension in Japanese females
Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion
Linkage and association mapping of the LRP5 locus on chromosome 11q13 in type 1 diabetes
LRP6 mutation in a family with early coronary disease and metabolic risk factors
LRP5 regulates human body fat distribution by modulating adipose progenitor biology in a dose- and depot-specific fashion
LRP5 mutations linked to high bone mass diseases cause reduced LRP5 binding and inhibition by SOST
LRP5 in premature adrenarche and in metabolic characteristics of prepubertal children
LDL-receptor-related proteins in Wnt signal transduction
LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription
Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling
Insulin treatment and high-fat diet feeding reduces the expression of three Tcf genes in rodent pancreas
Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition
Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
Increased glutamine catabolism mediates bone anabolism in response to WNT signaling
Impact of hormone replacement on myocardial fatty acid metabolism: potential role of estrogen
Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease
Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of beta-catenin/Arm and stimulation of target gene expression
High bone mass in mice expressing a mutant LRP5 gene
High bone density due to a mutation in LDL-receptor-related protein 5
HIF-<TEX>$1{\alpha}$</TEX> promotes glutamine-mediated redox homeostasis and glycogen-dependent bioenergetics to support postimplantation bone cell survival
Glutamine metabolism in bone
Glucose uptake and runx2 synergize to orchestrate osteoblast differentiation and bone formation
Glucose transporter-4 facilitates insulin-stimulated glucose uptake in osteoblasts
Glucose metabolism and collagen biosynthesis
G-protein beta 3 subunit polymorphism C1429T and low-density lipoprotein receptor-related protein 5 polymorphism A1330V are risk factors for hypercholesterolemia in Japanese males: a prospective study over 5 years
Functional interaction of beta-catenin with the transcription factor LEF-1
Fatty acid oxidation in bone tissue and bone cells in culture. Characterization and hormonal influences
Fatty acid oxidation by the osteoblast is required for normal bone acquisition in a sex- and diet-dependent manner
Essential role of beta-catenin in postnatal bone acquisition
Emerging concepts of the structure and metabolic functions of bone
Effects of parathyroid hormone on Wnt signaling pathway in bone
Effect of ovarian hormones on mitochondrial enzyme activity in the fat oxidation pathway of skeletal muscle
Drosophila Tcf and Groucho interact to repress Wingless signaling activity
Distinct Wnt signaling pathways have opposing roles in appendage regeneration
Disruption of LRP6 in osteoblasts blunts the bone anabolic activity of PTH
Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand
Development of the endochondral skeleton
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability
Current Understanding on Role of the Wnt Signaling Pathway Effector TCF7L2 in Glucose Homeostasis
Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals
Combination of the C1429T polymorphism in the G-protein beta-3 subunit gene and the A1330V polymorphism in the low-density lipoprotein receptor-related protein 5 gene is a risk factor for hypercholesterolaemia
Cloning of a novel member of the low-density lipoprotein receptor family
Cellular energy utilization and molecular origin of standard metabolic rate in mammals
Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor
Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes
Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation
Ca(2+)/calmodulin-dependent protein kinase II is stimulated by Wnt and Frizzled homologs and promotes ventral cell fates in Xenopus
Building strong bones: molecular regulation of the osteoblast lineage
Bone density ligand, sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity
Bioenergetics during calvarial osteoblast differentiation reflect strain differences in bone mass
Bioenergetics and mitochondrial transmembrane potential during differentiation of cultured osteoblasts
Beta-catenin is a target for the ubiquitin-proteasome pathway
Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin
Axin, a negative regulator of the Wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin
Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes
Association of the APC gene product with beta-catenin
Arrow encodes an LDL-receptor-related protein essential for Wingless signalling
Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development
An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: applications in mice with bone property altering Lrp5 mutations
An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin
Alternative Wnt pathways and receptors
Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism
Aerobic glycolysis in bone: lactate production and gradients in calvaria
Adipose tissue TCF7L2 splicing is regulated by weight loss and associates with glucose and fatty acid metabolism
Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development
Absence of glutamine supplementation prevents differentiation of murine calvarial osteoblasts to a mineralizing phenotype
Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice
A new member of the frizzled family from Drosophila functions as a Wingless receptor
A new low density lipoprotein receptor related protein, LRP5, is expressed in hepatocytes and adrenal cortex, and recognizes apolipoprotein E
A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait
A member of the Frizzled protein family mediating axis induction by Wnt-5A
A hierarchy of ATP-consuming processes in mammalian cells
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
<TEX>$\beta$</TEX>-Catenin directs long-chain fatty acid catabolism in the osteoblasts of male mice
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Regulation of Osteoblast Metabolism by Wnt Signaling'
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