osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

a novel secreted protein involved in the regulation of bone density

Type I collagen: Structure, synthesis and regulation.

The molecular clock mediates leptin-regulated bone formation

The biochemistry of bone

TRANCE is a TNF family member that regulates dendritic cell and osteoclast function

Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/ osteoprotegerin

Role of osteoblasts in hormonal control of bone resorption--a hypothesis

Rates of bone loss in the appendicular and axial skeletons of women Evidence of substantial vertebral bone loss before menopause

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

RANK is essential for osteoclast and lymph node development

Quantitative computed tomography of vertebral spon- giosa a sensitive method for detecting early bone loss after oophorectomy

Parathyroid hormone stimulates bone formation and resorption in organ culture evidence for a coupling mechanism

Ovarian steroid treatment blocks a postmenopausal increase in blood monocyte interleukin 1 release

Osteoprotegerin ligand: a common link between osteoclastogenesis, lymph node formation and lymphocyte development

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

Osteopontin and related phosphorylated sialoproteins

Osteoclastogenesis inhibitory factor exhibits hypocalcemic effects in normal mice and in hypercalcemic nude mice carrying tumors associated with humoral hypercalcemia of malignancy

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

Mineralization by matrix vesicles

Mineral and collagen-binding proteins of fetal calf bone

Mediators of the biphasic responses of bone to intermittent and continuously administered parathyroid hormone

Mechanism of calcification role of collagen fibrils and collagen-phosphoprotein complexes in vitro and in vivo

Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse

Leptin regulation of bone resorption by the sympathetic nervous system and CART

LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development.

Is all bone the same? Distinctive distributions and properties of non-collagenous matrix proteins in lamellar vs woven bone imply the existence of different underlying osteogenic mechanisms

Inhibition of TGF-beta receptor signaling in osteoblasts leads to decreased bone remodeling and increased trabecular bone mass

Infusions of recombinant human interleukins 1 alpha and 1 beta cause hypercalcemia in normal mice

Induction of osteoclast differentiation by Runx2 through receptor activator of nuclear factor- kappaB ligand and osteoprotegerin regulation and partial rescue of osteoclastogenesis in Runx2-/- mice by RANKL transgene

In vivo stimulation of bone formation by transforming growth factor-beta

Identifying genes that regulate bone remo- deling as potential therapeutic targets

Hypocalcemic effect of osteoclastogenesis inhibitory factor/osteoprotegerin in the thyroparathyroidectomized rat

Growth factors regulate the synthesis of insulin-like growth factor-I in bone cell cultures

Growth factors and the regulation of bone remodeling

Extracellular matrix and biomineralization of bone

Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shed- ding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival.

Dynamics of bone remodeling

Characterization of the latent transforming growth factor beta complex in bone

Characterization of native and recombinant bone sialoprotein delineation of the mineral-binding and cell adhesion domains and structural analysis of the RGD domain

Basic principles and clinical applications of biochemical markers of bone metabolism

A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait