Toxicological studies of SUNACTIVE Zn-P240 and SUNACTIVE Fe-P80 = SUNACTIVE Zn-P240과 SUNACTIVE Fe-P80의 독성학적 연구

임정현 2022년
논문상세정보
' Toxicological studies of SUNACTIVE Zn-P240 and SUNACTIVE Fe-P80 = SUNACTIVE Zn-P240과 SUNACTIVE Fe-P80의 독성학적 연구' 의 주제별 논문영향력
논문영향력 선정 방법
논문영향력 요약
주제
  • 축산
  • Genotoxicity
  • Repeated oral dose toxicity
  • SUNACTIVE Fe-P80
  • SUNACTIVE Zn-P240
동일주제 총논문수 논문피인용 총횟수 주제별 논문영향력의 평균
887 0

0.0%

' Toxicological studies of SUNACTIVE Zn-P240 and SUNACTIVE Fe-P80 = SUNACTIVE Zn-P240과 SUNACTIVE Fe-P80의 독성학적 연구' 의 참고문헌

  • Zinc-associated acute pancreatitis in a dog
  • Zinc toxicity : does it exist ?
    Leonard , A. , Gerber , G.B. 8 , 1285 ? 1290 [1989]
  • Zinc requirements and the risks and benefits of zinc supplementation .
    Maret , W. , Sandstead , H.H. 20 , 3 ? 18 [2006]
  • Zinc in the fetus and newborn . Acta Paediatr Scand Suppl
    Simmer , K. , Thompson , R.P.H. 319 , 158 ? 163 . [1985]
  • Zinc homeostasis and neuro degenerative disorders
    Szewczyk , B. 5 , 33 . [2013]
  • Zinc gluconate : acute ingestion
    Lewis , M.R. , Kokan , L. 36 , 99 ? 101 [1998]
  • Zinc deficiency in women , infants and children
    Prasad , A.S. 15 , 113 ? 120 [1996]
  • Zinc deficiency and taste disorders
    Heyneman , C.A. 30 , 186 ? 187 . [1996]
  • Zinc deficiency : its characterization and treatment
    Prasad , A.S. 41 , 103 ? 138 [2004]
  • Zinc deficiency : a special challenge
    Hambidge , K.M. , Krebs , N.F. 137 , 1101-1105 . [2007]
  • Zinc and the immune system
    Rink , L. 59 , 541 ? 552 [2000]
  • Zinc and growth
    Nishi , Y. 15 , 340 ? 344 [1996]
  • Zinc : an overview
    Prasad , A.S. 11 , 93 ? 99 [1995]
  • Zinc , human diseases and aging
    Fabris , N. , Mocchegiani , E. 7 , 77 ? 93 . [1995]
  • Zhao, C. Y., Tan, S. X., Xiao, X. Y., Qiu, X. S., Pan, J. Q., Tang, Z. X., 2014. Effects of dietary zinc oxide nanoparticles on growth performance and antioxidative status in broilers. Biol. Trace Elem. Res. 160, 361–367.
    [2014]
  • Yu, W.J., Chung, M.K., Chung, Y.H., Kim, H.C., Kim, S.H., Lee, I.C., Kim, J.C., 2011. One-generation reproductive toxicity study of 2-methylbutane in Sprague–Dawley rats. Regul. Toxicol. Pharmacol. 60, 136–143.
    [2011]
  • Yan, G., Huang, Y., Bu, Q., Lv L, Deng, P., Zhou, J., Wang, Y., Yang, Y., Liu, Q., Cen, X., Zhao, Y., 2012. Zinc oxide nanoparticles cause nephrotoxicity and kidney metabolism alterations in rats. J. Environ. Sci. Health 47, 577–588.
    [2012]
  • Xie, G., Sun, J., Zhong, G., Shi, L., Zhang, D., 2010. Biodistribution and toxicity of intravenously administered silica nanoparticles in mice. Arch. Toxicol. 84, 183–190.
    [2010]
  • Wilhelm, C., Billotey, C., Roger, J., Pons, J.N., Bacri, J.C., Gazeau, F., 2003. Intracellular uptake of anionic superparamagnetic nanoparticles as a function of their surface coating. Biomaterials 24, 1001–1011.
    [2003]
  • Wallig, M.A., Bolon, B., Haschek, W.M., Rousseaux, C.G., 2017. Fundamentals of Toxicologic Pathology. Academic press, Cambridge.
    [2017]
  • Wagner, A.J., Bleckmann, C.A., Murdock, R.C., Schrand, A.M., Schlager, J.J., Hussain, S.M., 2007. Cellular interaction of different forms of aluminum nanoparticles in rat alveolar macrophages. J. Phys. Chem. B 111, 7353–7359.
    [2007]
  • WHO, 2010. FAO/WHO expert meeting on the application of nanotechnologies in the food and agriculture sectors: potential food safety implications: meeting report. World Health Organization.
    [2010]
  • WHO, 2008. Worldwide prevalence of anaemia 1993-2005: WHO global database on anaemia.
    [2008]
  • WHO, 2002. The world health report. World Health Organization.
    [2002]
  • Valdiglesias, V., Costa, C., Sharma, V., Kiliç, G., Pásaro, E., Teixeira, J.P., Dhawan, A., Laffon, B., 2013. Comparative study on effects of two different types of titanium dioxide nanoparticles on human neuronal cells. Food Chem. Toxicol. 57, 352–361.
    [2013]
  • Use of ranks in one criterion variance analysis
    Kruskal , W.H. , Wallis , W.A. 47 , 583 ? 621 . [1952]
  • Unfried, K., Albrecht, C., Klotz, L.-O., Von Mikecz, A., Grether-Beck, S., Schins, R.P.F., 2007. Cellular responses to nanoparticles: target structures and mechanisms. Nanotoxicology 1, 52–71.
    [2007]
  • Understanding zinc : recent observations and interpretations
    Sandstead , H.H. 124 , 322 ? 327 [1994]
  • Trumbo, P., Yates, A.A., Schlicker, S., Poos, M., 2001. Dietary reference intakes: vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. J. Am. Diet. Assoc. 101, 294–301.
    [2001]
  • Torabi, M., Kesmati, M., Harooni, H.E., Varzi, H.N., 2013. Effects of nano and conventional zinc oxide on anxiety-like behavior in male rats. Indian J. Pharmacol. 45, 508–512.
    [2013]
  • Thoolen, B., Maronpot, R.R., Harada, T., Nyska, A., Rousseaux, C., Nolte, T., Malarkey, D.E., Kaufmann, W., Küttler, K., Deschl, U., 2010. Proliferative and nonproliferative lesions of the rat and mouse hepatobiliary system. Toxicol. Pathol. 38, 5S–81S.
    [2010]
  • The role of zinc in growth and cell proliferation .
    MacDonald , R.S. 130 , 1500S ? 1508S [2000]
  • The role of iron and reactive oxygen species in cell death
  • The long history of iron in the Universe and in health and disease .
  • The in vitro chromosomal aberration test using Chinese hamster lung ( CHL ) fibroblast cells in culture
    Ishidate Jr , M. 5 , 427 ? 432 [1985]
  • The Ames/Salmonella/microsome mutagenicity assay
    Mortelmans , K. , Zeiger , E. 455 , 29 ? 60 . [2000]
  • Suttie, A.W., Leininger, J.R., Bradley, A.E., 2017. Boorman’s Pathology of the Rat. Elsevier, Amsterdam.
    [2017]
  • Studies on growth , copper metabolism of rats fed high levels of zinc
    Magee , A.C. , Matrone , G. J. Nutr.72 , 233 ? 242 [1960]
  • Straube, E.F., Schuster, N.H., Sinclair, A.J., 1980. Zinc toxicity in the ferret. J. Comp. Pathol. 90, 355–361.
    [1980]
  • Srinivas, P.R., Philbert, M., Vu, T.Q., Huang, Q., Kokini, J.L., Saltos, E., 2010. Nanotechnology research: applications in nutritional sciences. J. Nutr. 140, 119–124.
    [2010]
  • Shin, H.J., Cho, H.G., Park, C.K., Park, K.H., Lim, H. Bin, 2017. Comparative in vitro biological toxicity of four kinds of air pollution particles. Toxicol. Res. 33, 305–313.
    [2017]
  • Sharifi, S., Behzadi, S., Laurent, S., Forrest, M.L., Stroeve, P., Mahmoudi, M., 2012. Toxicity of nanomaterials. Chem. Soc. Rev. 41, 2323–2343.
    [2012]
  • Schulze, E., Ferrucci Jr, J.T., Poss, K., Lapointe, L., Bogdanova, A., Weissleder, R., 1995. Cellular uptake and trafficking of a prototypical magnetic iron oxide label in vitro. Invest. Radiol. 30, 604–610.
    [1995]
  • Schrand, A.M., Huang, H., Carlson, C., Schlager, J.J., Ōsawa, E., Hussain, S.M., Dai, L., 2007. Are diamond nanoparticles cytotoxic? J. Phys. Chem. B 111, 2–7.
    [2007]
  • Schrand, A.M., Braydich-Stolle, L.K., Schlager, J.J., Dai, L., Hussain, S.M., 2008. Can silver nanoparticles be useful as potential biological labels? Nanotechnology 19, 235104.
    [2008]
  • Sayes, C.M., Gobin, A.M., Ausman, K.D., Mendez, J., West, J.L., Colvin, V.L., 2005. Nano- C60 cytotoxicity is due to lipid peroxidation. Biomaterials 26, 7587–7595.
    [2005]
  • Savolainen, K., Pylkkänen, L., Norppa, H., Falck, G., Lindberg, H., Tuomi, T., Vippola, M., Alenius, H., Hämeri, K., Koivisto, J., 2010. Nanotechnologies, engineered nanomaterials and occupational health and safety–A review. Saf. Sci. 48, 957–963.
    [2010]
  • Savolainen, K., Alenius, H., Norppa, H., Pylkkänen, L., Tuomi, T., Kasper, G., 2010. Risk assessment of engineered nanomaterials and nanotechnologies–a review. Toxicology 269, 92–104.
    [2010]
  • Sanders, K., Degn, L.L., Mundy, W.R., Zucker, R.M., Dreher, K., Zhao, B., Roberts, J.E., Boyes, W.K., 2012. In vitro phototoxicity and hazard identification of nano-scale titanium dioxide. Toxicol. Appl. Pharmacol. 258, 226–236.
    [2012]
  • Rossi, M., Cubadda, F., Dini, L., Terranova, M.L., Aureli, F., Sorbo, A., Passeri, D., 2014. Scientific basis of nanotechnology, implications for the food sector and future trends. Trends Food Sci. Technol. 40, 127–148.
    [2014]
  • Ross, A.C., Caballero, B., Cousins, R.J., Tucker, K.L., Ziegler, T.R., 2012. Modern Nutrition in Health and Disease. Lippincott Williams & Wilkins, London.
    [2012]
  • Ross, A.C., Caballero, B., Cousins, R.J., Tucker, K.L., Ziegler, T.R., 2012. Modern Nutrition in Health and Disease. Lippincott Williams & Wikins.
    [2012]
  • Revised methods for the Salmonella mutagenicity test
    Maron , D.M. , Ames , B.N. 113 , 173 ? 215 [1983]
  • Report : priorities in the assessment of vitamin A and iron status and in populations
    WHO Panama , 15-17 September 2010 [2012]
  • Relationships between organ weight and body/brain weight in the rat : what is the best analytical endpoint ?
  • Raya, S.D.H.A., Hassan, M.I., Farroh, K.Y., Hashim, S.A., Salaheldin, T.A., 2016. Zinc oxide nanoparticles fortified biscuits as a nutritional supplement for zinc deficient rats. J. Nanomed. Res. 4, 81.
    [2016]
  • Raya, S., Hassan, M.I., Farroh, K.Y., Hashim, S.A., Salaheldin, T.A., 2016. Zinc oxide nanoparticles fortified biscuits as a nutritional supplement for zinc deficient rats. J. Nanomed. Res 4, 00081.
    [2016]
  • Prasad, A.S., Beck, F.W., Grabowski, S.M., Kaplan, J., Mathog, R.H., 1997. Zinc deficiency: changes in cytokine production and T-cell subpopulations in patients with head and neck cancer and in noncancer subjects. Proc. Assoc. Am. Physicians 109, 68–77.
    [1997]
  • Physical approaches for the delivery of active ingredients in foods
    Ubbink , J. , Kr ? ger , J. 17 , 244 ? 254 [2006]
  • Perez, J.M., Asati, A., Nath, S., Kaittanis, C., 2008. Synthesis of biocompatible dextrancoated nanoceria with pH‐dependent antioxidant properties. Small 4, 552–556.
    [2008]
  • Pantarotto, D., Partidos, C.D., Graff, R., Hoebeke, J., Briand, J.-P., Prato, M., Bianco, A., 2003. Synthesis, structural characterization, and immunological properties of carbon nanotubes functionalized with peptides. J. Am. Chem. Soc. 125, 6160–6164.
    [2003]
  • Pantarotto, D., Briand, J.-P., Prato, M., Bianco, A., 2004. Translocation of bioactive peptides across cell membranes by carbon nanotubes. Chem. Commun. 16–17.
    [2004]
  • Pancreatic fibrosis associated with zinc toxicosis in a dog .
  • PEGylated nanoparticles for biological and pharmaceutical applications
  • On a test of whether one of two random variables is stochastically larger than the other .
  • Ogiso, T., Moriyama, K., Sasaki, S., Ishimura, Y., Minato, A., 1974. Inhibitory effect of high dietary zinc on copper absorption in rats. Chem. Pharm. Bull. (Tokyo) 22, 55–60.
    [1974]
  • Oberdörster, G., Oberdörster, E., Oberdörster, J., 2005. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ. Health Perspect. 113, 823–839.
    [2005]
  • OECD, 2020. Guidelines for Testing of Chemicals. TG 471: Bacterial Reverse Mutation Test. OECD, Paris.
    [2020]
  • OECD, 2014. Guidelines for Testing of Chemicals. TG 474: Mammalian Erythrocyte Micronucleus Test. OECD, Paris.
    [2014]
  • OECD, 2008. Guidelines for Testing of Chemicals. TG 407: Repeated Dose 28-day Oral Dose Toxicity Study in Rodents. OECD, Paris.
    [2008]
  • OECD, 1997. Guidelines for Testing of Chemicals. TG 473: In Vitro Mammalian Chromosomal Aberration Test. OECD, Paris.
    [1997]
  • New tables for multiple comparisons with a control
    Dunnett , C. W. 20 , 482 ? 491 [1964]
  • Nel, A., Xia, T., Mädler, L., Li, N., 2006. Toxic potential of materials at the nanolevel. Science 311, 622–627.
    [2006]
  • NRC, 2011. Guide for the Care and Use of Laboratory Animals. National Research Council. National Academy Press, Washington DC.
    [2011]
  • NRC, 2011. Guide for the Care and Use of Laboratory Animals. National Academy Press, Washington DC.
    [2011]
  • Møller, P., Jacobsen, N.R., Folkmann, J.K., Danielsen, P.H., Mikkelsen, L., Hemmingsen, J.G., Vesterdal, L.K., Forchhammer, L., Wallin, H., Loft, S., 2010. Role of oxidative damage in toxicity of particulates. Free Radic. Res. 44, 1–46.
    [2010]
  • Morris, M.C., Gros, E., Aldrian-Herrada, G., Choob, M., Archdeacon, J., Heitz, F., Divita, G., 2007. A non-covalent peptide-based carrier for in vivo delivery of DNA mimics. Nucleic Acids Res. 35, e49.
    [2007]
  • Moon, H.S., Guo, D.D., Song, H.H., Kim, I.Y., Jin, H.L., Kim, Y.K., Chung, C.S., Choi, Y.J., Lee, H.K., Cho, C.S., 2007. Regulation of adipocyte differentiation by PEGylated all-trans retinoic acid: reduced cytotoxicity and attenuated lipid accumulation. J. Nutr. Biochem. 18, 322–331.
    [2007]
  • Mild human zinc deficiency produces an imbalance between cellmediated and humoral immunity
    Solomons , N.W. 56 , 27 ? 28 [1998]
  • Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test .
  • Mechanisms of trace metal accumulation in the polychaete Neanthes arenaceodentata
  • Manoguerra, A.S., Erdman, A.R., Booze, L.L., Christianson, G., Wax, P.M., Scharman, E.J., Woolf, A.D., Chyka, P.A., Keyes, D.C., Olson, K.R., 2005. Iron ingestion: an evidencebased consensus guideline for out-of-hospital management. Clin. Toxicol. 43, 553–570.
    [2005]
  • Maita, K., Hirano, M., Mitsumori, K., Takahashi, K., Shirasu, Y., 1981. Subacute toxicity studies with zinc sulfate in mice and rats. J. Pestic. Sci. 6, 327–336.
    [1981]
  • Mahmoudi, M., Azadmanesh, K., Shokrgozar, M.A., Journeay, W.S., Laurent, S., 2011. Effect of nanoparticles on the cell life cycle. Chem. Rev. 111, 3407–3432.
    [2011]
  • Mahler, G.J., Esch, M.B., Tako, E., Southard, T.L., Archer, S.D., Glahn, R.P., Shuler, M.L., 2012. Oral exposure to polystyrene nanoparticles affects iron absorption. Nat. Nanotechnol. 7, 264–271.
    [2012]
  • MHW, 2020. Dietary Reference Intakes for Koreans 2020. Sejong, Ministry of Health and Welfare, Republic of Korea.
    [2020]
  • MFDS, 2017. Good Laboratory Practice Regulation for Non-clinical Laboratory Studies Notification No. 2017-32. Ministry of Food and Drug Safety, Republic of Korea.
    [2017]
  • Lynch, S., Pfeiffer, C.M., Georgieff, M.K., Brittenham, G., Fairweather-Tait, S., Hurrell, R.F., McArdle, H.J., Raiten, D.J., 2018. Biomarkers of Nutrition for Development (BOND) iron review. J. Nutr. 148, 1001S-1067S.
    [2018]
  • Lockman, P.R., Koziara, J.M., Mumper, R.J., Allen, D.D., 2004. Nanoparticle surface charges alter blood–brain barrier integrity and permeability. J. Drug Target. 12, 635– 641.
    [2004]
  • Lieder, P.H., Chang, S.C., York, R.G., Butenhoff, J.L., 2009. Toxicological evaluation of potassium perfluorobutanesulfonate in a 90-day oral gavage study with Sprague– Dawley rats. Toxicology 255, 45–52.
    [2009]
  • Lemarchand, C., Gref, R., Lesieur, S., Hommel, H., Vacher, B., Besheer, A., Maeder, K., Couvreur, P., 2005. Physico-chemical characterization of polysaccharide-coated nanoparticles. J. Control. Release 108, 97–111.
    [2005]
  • Lee, M.J., Jung, H.K., Lee, K.H., Jang, J.H., Sim, M.O., Seong, T.G., Shon, J.H., Ahn, B.K., Ham, S.H., Cho, H.W., Kim, Y.M., Park, S.G., Ko, J.W., Kim, J.C., 2019. A 90-day repeated oral dose toxicity study of Alismatis rhizoma aqueous extract in rats. Toxicol Res. 35, 191–200.
  • Lee, M.J., Jung, H.K., Lee, K.H., Jang, J.H., Sim, M.O., Seong, T.G., Ahn, B.K., Shon, J.H., Ham, S.H., Cho, H.W., Kim, Y.M., Park, S.J., Yoon, J.Y., Ko, J.W., Kim, J.C., 2019. A 90-day repeated oral dose toxicity study of Alismatis rhizoma aqueous extract in rats. Toxicol Res. 35, 191–200.
  • Lee, J.M., Lee, M.A., Do, H.N., Song, Y.I., Lee, H.Y., Park, S.H., Kang, J.S., Kang, J.K., 2012. Historical control data from 13-week repeated toxicity studies in Crj: CD (SD) rats. Lab. Anim. Res. 28, 115–121.
    [2012]
  • Lee, J.M., Lee, M.A., Do, H.N., Song, Y.I., Bae, R.J., Lee, H.Y., Park, S.H., Kang, J.S., Kang, J.K., 2012. Historical control data from 13-week repeated toxicity studies in Crj:CD (SD) rats. Lab. Anim. Res. 28, 115–121.
    [2012]
  • Lamprecht, A., Saumet, J.L., Roux, J., Benoit, J.P., 2004. Lipid nanocarriers as drug delivery system for ibuprofen in pain treatment. Int. J. Pharm. 278, 407–414.
    [2004]
  • Ko, J.W., Hong, E.T., Lee, I.C., Park, S.H., Park, J.I., Seong, N.W., Hong, J.S., Yun, H.I., Kim, J.C., 2015. Evaluation of 2-week repeated oral dose toxicity of 100 nm zinc oxide nanoparticles in rats. Lab. Anim. Res. 31, 139–147.
    [2015]
  • Kisin, E.R., Murray, A.R., Keane, M.J., Shi, X.-C., Schwegler-Berry, D., Gorelik, O., Arepalli, S., Castranova, V., Wallace, W.E., Kagan, V.E., 2007. Single-walled carbon nanotubes: geno-and cytotoxic effects in lung fibroblast V79 cells. J. Toxicol. Environ. Heal. Part A 70, 2071–2079.
    [2007]
  • Kirsch-Volders, M., Sofuni, T., Aardema, M., Albertini, S., Eastmond, D., Fenech, M., Ishidate Jr, M., Kirchner, S., Lorge, E., Morita, T., 2003. Report from the in vitro micronucleus assay working group. Mutat. Res. Toxicol. Environ. Mutagen. 540, 153– 163.
    [2003]
  • Kirchner, C., Liedl, T., Kudera, S., Pellegrino, T., Muñoz Javier, A., Gaub, H.E., Stölzle, S., Fertig, N., Parak, W.J., 2005. Cytotoxicity of colloidal CdSe and CdSe/ZnS nanoparticles. Nano Lett. 5, 331–338.
    [2005]
  • Kim, J.Y., Ri, Y., Do, S.G., Lee, Y.C., Park, S.J., 2014. Evaluation of the genotoxicity of ginseng leaf extract UG0712. Lab. Anim. Res. 30, 104–111.
    [2014]
  • Kim, H.J., Bae, S.H., Kim, H.J., Kim, K.M., Song, J.H., Go, M.R., Yu, J., Oh, J.M., Choi, S.J., 2017. Cytotoxicity, intestinal transport, and bioavailability of dispersible iron and zinc supplements. Front. Microbiol. 8, 749.
    [2017]
  • Khan, M.I., Mohammad, A., Patil, G., Naqvi, S.A.H., Chauhan, L.K.S., Ahmad, I., 2012. Induction of ROS, mitochondrial damage and autophagy in lung epithelial cancer cells by iron oxide nanoparticles. Biomaterials 33, 1477–1488.
    [2012]
  • Kato, T., Yashiro, T., Murata, Y., Herbert, D.C., Oshikawa, K., Bando, M., Ohno, S., Sugiyama, Y., 2003. Evidence that exogenous substances can be phagocytized by alveolar epithelial cells and transported into blood capillaries. Cell Tissue Res. 311, 47– 51.
    [2003]
  • Karlsson, H.L., Gustafsson, J., Cronholm, P., Möller, L., 2009. Size-dependent toxicity of metal oxide particles–a comparison between nano-and micrometer size. Toxicol. Lett. 188, 112–118.
    [2009]
  • Joseph, T., Morrison, M., 2006. Nanoforum Report: Nanotechnology in Agriculture and Food. Wolverhampton: Institute of Nanotechnology.
    [2006]
  • Jain, A., Ranjan, S., Dasgupta, N., Ramalingam, C., 2018. Nanomaterials in food and agriculture: an overview on their safety concerns and regulatory issues. Crit. Rev. Food Sci. Nutr. 58, 297–317.
    [2018]
  • JEMS-MMS, 1988. Japanese Environmental Mutagen Society-Mammalian Mutagenicity Study group. Atlas of chromosome aberration by chemicals. Tokyo, Japan; JEMSMMS; 1988.
    [1988]
  • Ishihara, K., Yamanami, K., Takano, M., Suzumura, A., Mita, Y., Oka, T., Juneja, L.R., Yasumoto, K., 2008. Zinc bioavailability is improved by the micronised dispersion of zinc oxide with the addition of L-histidine in zinc-deficient rats. J. Nutr. Sci. Vitaminol. 54, 54–60.
    [2008]
  • Ishihara, K., Yamanami, K., Takano, M., Suzumura, A., Mita, Y., Oka, T., Juneja, L.R., Yasumoto, K., 2008. Zinc bioavailability is improved by the micronised dispersion of zinc oxide with the addition of L-histidine in zinc-deficient rats. J. Nutr. Sci. Vitaminol. (Tokyo). 54, 54–60.
  • Iron poisoning : a literature-based review of epidemiology , diagnosis , and management . Pediatr . Emerg
    Chang , T.P.Y. , Rangan , C. Care 27 , 978 ? 985 . [2011]
  • Iron deficiency anemia .
    Clark , S.F. 23 , 128 ? 141 [2008]
  • Iron and zinc interactions in humans .
    Whittaker , P. 68 , 442S-446S . [1998]
  • In vitro assessments of nanomaterial toxicity
    Jones , C.F. , Grainger , D.W. 61 , 438 ? 456 . [2009]
  • Impact of the discovery of human zinc deficiency on health
    Prasad , A.S. 28 , 357 ? 363 [2014]
  • IOM, 2001. Dietary Reference Intakes: Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. National Academy Press, Washington DC.
    [2001]
  • IOM, 2001. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. National Academy Press, Washington DC.
    [2001]
  • ICH, 2009. M3(R2) Guidance on Non-clinical Safety Studies for the Conduct of Human Clinical Trials and Marketing Authorization for Pharmaceuticals.
    [2009]
  • Hoshino, A., Fujioka, K., Oku, T., Suga, M., Sasaki, Y.F., Ohta, T., Yasuhara, M., Suzuki, K., Yamamoto, K., 2004. Physicochemical properties and cellular toxicity of nanocrystal quantum dots depend on their surface modification. Nano Lett. 4, 2163– 2169.
    [2004]
  • Hooper, P.L., Visconti, L., Garry, P.J., Johnson, G.E., 1980. Zinc lowers high-density lipoprotein-cholesterol levels. JAMA 244, 1960–1961.
  • Heng, B.C., Zhao, X., Tan, E.C., Khamis, N., Assodani, A., Xiong, S., Ruedl, C., Ng, K.W., Loo, J.S.-C., 2011. Evaluation of the cytotoxic and inflammatory potential of differentially shaped zinc oxide nanoparticles. Arch. Toxicol. 85, 1517–1528.
    [2011]
  • Han, Z.Z., Xu, H.D., Kim, K.H., Ahn, T.H., Bae, J.S., Lee, J.Y., Gil, K.H., Lee, J.Y., Woo, S.J., Yoo, H.J., 2010. Reference data of the main physiological parameters in control Sprague-Dawley rats from pre-clinical toxicity studies. Lab. Anim. Res. 26, 153–164.
    [2010]
  • Han, T.K., Kim, D.Y., Nam, C., Moon, S.H., Park, S.H., Han, K.G., Lee, H.Y., Bae, H.M., Park, C.B., So, J.H., Kang, S., Kang, J.K., 2020. Acute and 13-week subchronic toxicity studies of hot-water extract of Cynanchi wilfordii Radix in Sprague-Dawley rats. Toxicol Res. 36, 89–98.
  • Han, C.T., Kim, D.Y., Nam, C., Moon, S.H., Park, S.H., Han, K.G., Lee, H.Y., Bae, H.M., Park, C.B., So, J.H., 2020. Acute and 13-week subchronic toxicity studies of hot-water extract of Cynanchi wilfordii Radix in Sprague-Dawley rats. Toxicol. Res. 36, 89–98.
    [2020]
  • Hambidge, K.M., 1989. Mild Zinc Deficiency in Human Subjects, in: Zinc in Human Biology. Springer, pp. 281–296.
    [1989]
  • Gupta, A.K., Gupta, M., 2005. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials 26, 3995–4021.
    [2005]
  • Greaves, P., 2011. Histopathology of Preclinical Toxicity Studies: Interpretation and Relevance in Drug Safety Evbaluation. Academic Press, Cambridge.
    [2011]
  • Greaves, P., 2011. Histopathology of Preclinical Toxicity Studies: Interpretation and Relevance in Drug Safety Evaluation. Academic Press.
    [2011]
  • Goodman, C.M., McCusker, C.D., Yilmaz, T., Rotello, V.M., 2004. Toxicity of gold nanoparticles functionalized with cationic and anionic side chains. Bioconjug. Chem. 15, 897–900.
    [2004]
  • Genotoxicity testing , a regulatory requirement for drug discovery and development : Impact of ICH guidelines
  • Functional materials in food nanotechnology
  • Frazier, K.S., Seely, J.C., Hard, G.C., Betton, G., Burnett, R., Nakatsuji, S., Nishikawa, A., Durchfeld-Meyer, B., Bube, A., 2012. Proliferative and nonproliferative lesions of the rat and mouse urinary system. Toxicol. Pathol. 40, 14S–86S.
    [2012]
  • Fortification : overcoming technical and practical barriers .
    Hurrell , R.F. 132 , 806S-812S [2002]
  • Foods & Nutrition Encyclopedia ( 2nd ed. ) . Boca Raton , Florida : CRC Press
    Ensminger , M.E. , Ensminger A.H. pp . 2368 ? 2369 [1993]
  • Fisher, R.A., 1992. Statistical Methods for Research Workers, in: Breakthroughs in Statistics. Springer, pp. 66–70.
    [1992]
  • Fisher, R.A., 1992. Statistical Methods for Research Workers, in: Breakthroughs in Statistics. Springer, Berlin, pp. 66–70.
    [1992]
  • Fisher, R.A., 1992. Statistical Methods for Research Workers, Breakthroughs in Statistics. Springer, pp. 66–70.
    [1992]
  • Fidler, M.C., Walczyk, T., Davidsson, L., Zeder, C., Sakaguchi, N., Juneja, L.R., Hurrell, R.F., 2004. A micronised, dispersible ferric pyrophosphate with high relative bioavailability in man. Br. J. Nutr. 91, 107–112.
    [2004]
  • Erdman, J.W., Macdonald, I.A., Zeisel, S.H., 2012. Present Knowledge in Nutrition. Wiley- Blackwell.
    [2012]
  • Erdman Jr, J.W., Macdonald, I.A., Zeisel, S.H., 2012. Present Knowledge in Nutrition. John Wiley & Sons.
    [2012]
  • Erdman Jr, J.W., Macdonald, I.A., Zeisel, S.H., 2012. Present Knowledge in Nutrition. John Wiley & Sons, Hoboken.
    [2012]
  • Elder, A., Lynch, I., Grieger, K., Chan-Remillard, S., Gatti, A., Gnewuch, H., Kenawy, E., Korenstein, R., Kuhlbusch, T., Linker, F., 2009. Human Health Risks of Engineered Nanomaterials, in: Nanomaterials: Risks and Benefits. Springer, Berlin, pp. 3–29.
    [2009]
  • Effect of marginal zinc deficiency on human growth and development
  • Dumortier, H., Lacotte, S., Pastorin, G., Marega, R., Wu, W., Bonifazi, D., Briand, J.P., Prato, M., Muller, S., Bianco, A., 2006. Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells. Nano Lett. 6, 1522–1528.
    [2006]
  • Disorders of iron metabolism : new diagnostic and treatment approaches to iron deficiency
    Powers , J.M. , Buchanan , G.R. 33 , 393 ? 408 [2019]
  • Disilvestro, R.A., 2004. Handbook of Minerals as Nutritional Supplements. CRC Press.
    [2004]
  • Discovery of human zinc deficiency : 50 years later
    Prasad , A.S. 26 , 66 ? 69 [2012]
  • Cushen, M., Kerry, J., Morris, M., Cruz-Romero, M., Cummins, E., 2014. Evaluation and simulation of silver and copper nanoparticle migration from polyethylene nanocomposites to food and an associated exposure assessment. J. Agric. Food Chem. 62, 1403–1411.
    [2014]
  • Crans, D.C., Woll, K.A., Prusinskas, K., Johnson, M.D., Norkus, E., 2013. Metal speciation in health and medicine represented by iron and vanadium. Inorg. Chem. 52, 12262–12275.
    [2013]
  • Competitive interaction of iron and zinc in the diet : consequences for human nutrition
    Solomons , N.W. 116 , 927 ? 935 [1986]
  • Cochran, W.G., 1952. The χ2 test of goodness of fit. Ann. Math. Stat. 315–345.
    [1952]
  • Coates, P.M., Betz, J.M., Blackman, M.R., Cragg, G.M., Levine, M., Moss, J., White, J.D., 2010. Encyclopedia of Dietary Supplements. CRC Press.
    [2010]
  • Chen, Q., Tang, S., Jin, X., Zou, J., Chen, K., Zhang, T., Xiao, X., 2009. Investigation of the genotoxicity of quinocetone, carbadox and olaquindox in vitro using Vero cells. Food Chem. Toxicol. 47, 328–334.
    [2009]
  • Chen, J., Patil, S., Seal, S., McGinnis, J.F., 2006. Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides. Nat. Nanotechnol. 1, 142–150.
    [2006]
  • Chen, C., Xing, G., Wang, J., Zhao, Y., Li, B., Tang, J., Jia, G., Wang, T., Sun, J., Xing, L., 2005. Multihydroxylated [Gd@C82(OH)22]n nanoparticles: antineoplastic activity of high efficiency and low toxicity. Nano Lett. 5, 2050–2057.
  • Chemical induction of sperm abnormalities in mice
    Wyrobek , A.J. , Bruce , W.R. 72 , 4425 ? 4429 [1975]
  • Chaudhry, Q., Scotter, M., Blackburn, J., Ross, B., Boxall, A., Castle, L., Aitken, R., Watkins, R., 2008. Applications and implications of nanotechnologies for the food sector. Food Addit. Contam. 25, 241–258.
    [2008]
  • Camaschella, C., 2015. Iron-deficiency anemia. N. Engl. J. Med. 372, 1832–1843.
    [2015]
  • Caballero, B., Cousins, R.J., Tucker, K.L., Ziegler, T.R., 2014. Modern Nutrition in Health and Disease. Lippincott Williams and Wikins, Philadelphia.
    [2014]
  • Brown, K.H., Wuehler, S.E., 2000. Zinc and Human Health: Results of Recent Trials and Implications for Program Interventions and Research. Ottawa, ON: International Development Research Centre.
    [2000]
  • Brown, K.H., Rivera, J.A., Bhutta, Z., Gibson, R.S., King, J.C., Lönnerdal, B., 2004. International Zinc Nutrition Consultative Group (IZiNCG) technical document #1. Assessment of the risk of zinc deficiency in populations and options for its control. Food Nutr. Bull. 25, S91–S204.
  • Botelho, M.C., Costa, C., Silva, S., Costa, S., Dhawan, A., Oliveira, P.A., Teixeira, J.P., 2014. Effects of titanium dioxide nanoparticles in human gastric epithelial cells in vitro. Biomed. Pharmacother. 68, 59–64.
    [2014]
  • Boorman, G.A., 1990. Pathology of The Fischer Rat: Reference and Alas. Academic Press.
    [1990]
  • Bogden, J.D., Oleske, J.M., Lavenhar, M.A., Munves, E.M., Kemp, F.W., Bruening, K.S., Holding, K.J., Denny, T.N., Guarino, M.A., Krieger, L.M., 1988. Zinc and immunocompetence in elderly people: effects of zinc supplementation for 3 months. Am. J. Clin. Nutr. 48, 655–663.
    [1988]
  • Biochemistry , physiology and pathology of zinc
    Vallee , B.L. 39 , 443 ? 490 [1959]
  • Biochemical functions of zinc in animals .
    Chesters , J.K. 32 , 135 ? 164 [1978]
  • Bianco, A., Kostarelos, K., Partidos, C.D., Prato, M., 2005. Biomedical applications of functionalised carbon nanotubes. Chem. Commun. 571–577.
    [2005]
  • Barnes, C.A., Elsaesser, A., Arkusz, J., Smok, A., Palus, J., Lesniak, A., Salvati, A., Hanrahan, J.P., Jong, W.H. de, Dziubałtowska, E., 2008. Reproducible comet assay of amorphous silica nanoparticles detects no genotoxicity. Nano Lett. 8, 3069–3074.
    [2008]
  • Applications of nanomaterials in food packaging with a consideration of opportunities for developing countries
  • Antidotes for zinc intoxication in mice
  • Andersen, H., Larsen, S., Spliid, H., Christensen N.D., 1999. Multivariate statistical analysis of organ weights in toxicity studies. Toxicology. 136, 67–77.
    [1999]
  • Allen, J.G., Masters, H.G., Peet, R.L., Mullins, K.R., Lewis, R.D., Skirrow, S.Z., Fry, J., 1983. Zinc toxicity in ruminants. J. Comp. Pathol. 93, 363–377.
    [1983]
  • Aggett, P. J., Crofton, R.W., Khin, C., Gvozdanovic, S., Gvozdanovic, D., 1983. The mutual inhibitory effects on their bioavailability of inorganic zinc and iron. Prog. Clin. Biol. Res. 129, 117–124.
    [1983]
  • Acrodermatitis enteropathica secondary to Crohn ’ s disease
    Krasovec , M. , Frenk , E. 193 , 361 ? 363 [1996]
  • Acquired acrodermatitis enteropathica . N. Engl
    Wang , L.C. , Busbey , S. 352 , 1121 . [2005]