'
Functional study of REDD1 as a novel therapeutic target for the ferroptosis-mediated liver fibrosis = 페롭토시스 매개 간섬유화의 신규 치료표적으로써 REDD1의 기능 연구' 의 주제별 논문영향력
논문영향력 요약
주제
Ferroptosis
Hepatic stellate cells
Liver fibrosis
REDD1
동일주제 총논문수
논문피인용 총횟수
주제별 논문영향력의 평균
101
0
0.0%
주제별 논문영향력
논문영향력
주제
주제별 논문수
주제별 피인용횟수
주제별 논문영향력
주제어
Ferroptosis
22
0
0.0%
Hepatic stellate cells
17
0
0.0%
Liver fibrosis
60
0
0.0%
REDD1
2
0
0.0%
계
101
0
0.0%
* 다른 주제어 보유 논문에서 피인용된 횟수
0
'
Functional study of REDD1 as a novel therapeutic target for the ferroptosis-mediated liver fibrosis = 페롭토시스 매개 간섬유화의 신규 치료표적으로써 REDD1의 기능 연구' 의 참고문헌
suppression." Nat Cell Biol 20(10): 1181-1192.
20 ( 10 ) : 1181-1192
``Cucurbitacin E ameliorates hepatic fibrosis in vivo and in vitro through activation of AMPK and blocking mTOR-dependent signaling pathway
258 : 147-158[2016]
``Cloning and expression of a plasma membraneCystine/glutamate exchange transporterComposed of two distinct proteins .
274 ( 17 ) : 11455-11458 .[1999]
``Characterization of ferroptosis in murine models of hemochromatosis .
66 ( 2 ) : 449- 465 .[2017]
``Ceruloplasmin suppresses ferroptosis by regulating iron homeostasis in hepatocellularCarcinomaCells .
72 : 109633 .[2020]
[ Free radicals in medicine and biology ]
58 ( 45 ) : 2670- 2675 .[1982]
Two to tango : regulation of Mammalian iron metabolism
142 ( 1 ) : 24-38 .[2010]
ThreeChemically distinct types of oxidants formed by ironmediated Fenton reactions in the presence of DNA
91 ( 26 ) : 12438- 12442[1994]
TheChanging landscape of hepatocellularCarcinoma : etiology , genetics , and therapy
184 ( 3 ) : 574-583 .[2014]
The role of redox-sensitive transcription factors NF-kappaB and AP-1 in the modulation of theCyp1a1 gene by mercury , lead , andCopper
44 ( 5 ) : 795-806 .[2008]
The role of iron and reactive oxygen species inCell death
10 ( 1 ) : 9-17 .[2014]
The role of TIMPs in regulation of extracellular matrix proteolysis .
[2015]
The retinoblastoma ( Rb ) protein regulates ferroptosis induced by sorafenib in human hepatocellularCarcinomaCells .
356 ( 2 Pt B ) : 971-977 .[2015]
The Roles of Mitogen-Activated Protein Kinase Pathways in TGF-beta-Induced Epithelial-Mesenchymal Transition .
2012 : 289243 .[2012]
Targeting Ferroptosisto Iron OutCancer .
35 ( 6 ) : 830-849 .[2019]
TGF-beta/Smad3 activates mammalian target of rapamycinComplex-1 to promoteCollagen production by increasing HIF-1alpha expression
305 ( 4 ) : F485-494 .[2013]
Synthetic lethal screening identifiesCompounds activating irondependent , nonapoptoticCell death in oncogenic-RAS-harboringCancerCells
15 ( 3 ) : 234-245 .[2008]
Stockwell, Friedmann Angeli, Bayir, Bush, Conrad, Dixon, Fulda, Gascon, Hatzios, Kagan, Noel, Jiang, Linkermann, Murphy, Overholtzer, Oyagi, Pagnussat, Park, Ran, Rosenfeld, Salnikow, Tang, Torti, Torti, Toyokuni, Woerpel and Zhang (2017). "Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease." Cell 171(2): 273-285.
Smad-dependent and Smad-independent pathways in TGF-beta family signalling
425 ( 6958 ) : 577-584 .[2003]
Sestrin2 : A Promising Therapeutic Target for Liver Diseases
38 ( 7 ) : 966-970[2015]
Selenoproteins ,Cholesterol-lowering drugs , and theConsequences : revisiting of the mevalonate pathway .
14 ( 7 ) : 273-281 .[2004]
Role of NADPH oxidases in liver fibrosis
20 ( 17 ) : 2854-2872 .[2014]
Reversal of HO-1 relatedCytoprotection with increased expression is due to reactive iron
Regulators of Iron Homeostasis : New Players in Metabolism ,Cell Death , and Disease
41 ( 3 ) : 274-286 .[2016]
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressorComplex .
18 ( 23 ) : 2893-2904 .[2004]
Regulation of ferroptoticCancerCell death by GPX4 .
156 ( 1-2 ) : 317-331 .[2014]
Regulation of MAPK activation , AP-1 transcription factor expression and keratinocyte differentiation in wounded fetal skin .
122 ( 3 ) : 791-804 .[2004]
RAS-RAF-MEK-dependent oxidativeCell death involving voltage-dependent anionChannels
447 ( 7146 ) : 864-868 .[2007]
Protective effect of sestrin2 against iron overload and ferroptosis-induced liver injury
[2019]
Predictive and preventive significance of AMPK activation on hepatocarcinogenesis in patients with liverCirrhosis
9 ( 3 ) : 264[2018]
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
113 ( 34 ) : E4966-4975 .[2016]
Pathogenesis of nonalcoholic steatohepatitis .
73 ( 10 ) : 1969-1987[2016]
Pathogenesis of liver fibrosis : role of oxidative stress
21 ( 3 ) : 49-98[2000]
Parthanatos : mitochondrial-linked mechanisms and therapeutic opportunities
171 ( 8 ) : 2000-2016[2014]
Oxidative stress-related molecules and liver fibrosis
35 ( 2 ) : 297-306 .[2001]
Oxidative and nitrosative stress and fibrogenic response
12 ( 4 ) : 769-790 , viii[2008]
Opposing roles for ATF2 andC-Fos inC-Jun-mediated neuronal apoptosis .
29 ( 9 ) : 2431-2442 .[2009]
Nrf2-ARE pathway regulates induction of Sestrin-2 expression
53 ( 4 ) : 834-841[2012]
Non-Smad pathways in TGF-beta signaling
19 ( 1 ) : 128-139 .[2009]
Negative feedbackControl of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis .
107 ( 10 ) : 4675-4680 .[2010]
Molecular recognition of aldehydes by aldehyde dehydrogenase and mechanism of nucleophile activation
57 ( 4 ) : 758-771 .[2004]
Molecular mechanism of hepatic stellateCell activation and antifibrotic therapeutic strategies
43 ( 6 ) : 419-428[2008]
Metallothionein-1G facilitates sorafenib resistance through inhibition of ferroptosis
64 ( 2 ) : 488-500 .[2016]
Mechanism of glycyrrhizin on ferroptosis during acute liver failure by inhibiting oxidative stress
20 ( 5 ) : 4081-4090 .[2019]
Massague (2012). "TGFbeta signalling in context." Nat Rev Mol Cell Biol 13(10): 616-630. McBean (2012). "The transsulfuration pathway: a source of cysteine for glutathione in astrocytes." Amino Acids 42(1): 199-205.
Loss ofCysteinyl-tRNAsynthetase (CARS ) induces the transsulfuration pathway and inhibits ferroptosis induced byCystine deprivation .
23 ( 2 ) : 270-278 .[2016]
LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellularCarcinomaCells
9 ( 1 ) : 16185 .[2019]
Llovet, Ricci, Mazzaferro, Hilgard, Gane, Blanc, de Oliveira, Santoro, Raoul, Forner, Schwartz, Porta, Zeuzem, Bolondi, Greten, Galle, Seitz, Borbath, Haussinger, Giannaris, Shan, Moscovici, Voliotis, Bruix and Group (2008). "Sorafenib in advanced hepatocellular carcinoma." N Engl J Med 359(4): 378-390.
Iron homeostasis
69 : 69-85 .[2007]
Iron and Immunity
55 : 355-375 .[2017]
IrondependentCell death of hepatocellularCarcinomaCells exposed to sorafenib
133 ( 7 ) : 1732-1742 .[2013]
Induction of REDD1 via AP-1 prevents oxidative stress-mediated injury in hepatocytes
124 : 221-231 .[2018]
Induction of E6AP by microRNA-302c dysregulation inhibits TGF-beta-dependent fibrogenesis in hepatic stellateCells
10 ( 1 ) : 444 .[2020]
Identification of genotype-selective antitumor agents using synthetic lethalChemical screening in engineered human tumorCells
3 ( 3 ) : 285-296 .[2003]
Identification of SimpleCompounds with Microtubule-Binding Activity That InhibitCancerCell Growth with High86 Potency
3 ( 1 ) : 35-38 .[2012]
Human HaploidCell Genetics Reveals Roles for Lipid Metabolism Genes in NonapoptoticCell Death
10 ( 7 ) : 1604-1609 .[2015]
Hepatic ferroptosis plays an important role as the trigger for initiating inflammation in nonalcoholic steatohepatitis
10 ( 6 ) : 449[2019]
Hepatic Iron Overload Induced by Phenylhydrazine : Release of Iron in a Free Form and DNA Damage
[1996]
Heme oxygenase-1 mediates BAY 11-7085 induced ferroptosis .
416 : 124-137 .[2018]
Heat stress induces ferroptosis-likeCell death in plants
216 ( 2 ) : 463-476 .[2017]
Haloperidol , a sigma receptor 1 antagonist , promotes ferroptosis in hepatocellularCarcinomaCells
491 ( 4 ) : 919-925 .[2017]
Glutathione peroxidases .
1830 ( 5 ) : 3289-3303 .[2013]
Glucocorticoid elevation of dexamethasone-induced gene 2 ( Dig2/RTP801/REDD1 ) protein mediates autophagy in lymphocytes
286 ( 34 ) : 30181-30189 .[2011]
Global survey ofCell death mechanisms reveals metabolic regulation of ferroptosis .
12 ( 7 ) : 497-503 .[2016]
Generation and biological activities of oxidized phospholipids
12 ( 8 ) : 1009-1059[2010]
Gene expression and regulation of plasminogen activator inhibitor type I in hepatic stellateCells of rat liver
111 ( 3 ) : 745-754 .[1996]
Geissler , Thomas , Stockwell , O'Donnell , Kagan , Schick and Conrad (
Inactivation of the ferroptosis regulator Gpx4 triggers[2014]
Gaschler, Andia, Liu, Csuka, Hurlocker, Vaiana, Heindel, Zuckerman, Bos, Reznik, Ye, Tyurina, Lin, Shchepinov, Chan, Peguero-Pereira, Fomich, Daniels, Bekish, Shmanai, Kagan, Mahal, Woerpel and Stockwell (2018). "FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation." Nat Chem Biol 14(5): 507-515.
Galpha12 overexpression induced by miR-16 dysregulationContributes to liver fibrosis by promoting autophagy in hepatic stellateCells
68 ( 3 ) : 493-504[2018]
Fibrogenic effect of oxidative stress on rat hepatic stellateCells
27 ( 3 ) : 720-726 .[1998]
Ferroptosis is governed by differential regulation of transcription in liverCancer
24 : 101211 .[2019]
Ferroptosis is Involved in Acetaminophen InducedCell Death .
21 ( 4 ) : 1115-1121 .[2015]
Ferroptosis Affects the Progression of Nonalcoholic Steatohepatitis via the Modulation of Lipid Peroxidation-MediatedCell Death in Mice
190 ( 1 ) : 68-81 .[2020]
Ferroptosis : process and function .
23 ( 3 ) : 369-379 .[2016]
Ferroptosis : an iron-dependent form of nonapoptoticCell death .
149 ( 5 ) : 1060-1072 .[2012]
Ferroptosis , a new form ofCell death , and its relationships with tumourous diseases
21 ( 4 ) : 648-657 .[2017]
Evidence for the presence of phospholipid hydroperoxide glutathione peroxidase in human platelets : implications for its involvement in the regulatory network of the 12-lipoxygenase pathway of arachidonic acid metabolism
353 ( Pt 1 ) : 91-100 .[2001]
Emerging insights into Transforming growth factor beta Smad signal in hepatic fibrogenesis
56 ( 2 ) : 284-292 .[2007]
E-cadherin antagonizes transforming growth factor beta1 gene induction in hepatic stellateCells by inhibiting RhoAdependent Smad3 phosphorylation
52 ( 6 ) : 2053-2064 .[2010]
Dexamethasone represses signaling through the mammalian target of rapamycin in muscleCells by enhancing expression of REDD1
281 ( 51 ) : 39128-39134 .[2006]
Development of small-molecule probes that selectively killCells induced to express mutant RAS
22 ( 4 ) : 1822-1826 .[2012]
BAP1 links metabolic regulation of ferroptosis to tumour
[2018]
Autophagy promotes ferroptosis by degradation of ferritin .
12 ( 8 ) : 1425-1428 .[2016]
Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellularCarcinomaCells
63 ( 1 ) : 173-184 .[2016]
Activation of rat hepatic stellateCells leads to loss of glutathione S-transferases and their enzymatic activity against products of oxidative stress
A mammalian protein targeted by G1-arresting rapamycin-receptorComplex .
369 ( 6483 ) : 756-758 .[1994]
'
Functional study of REDD1 as a novel therapeutic target for the ferroptosis-mediated liver fibrosis = 페롭토시스 매개 간섬유화의 신규 치료표적으로써 REDD1의 기능 연구'
의 유사주제(
) 논문