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Striatal transcriptomic analysis reveals the role of Nurr1 in synaptic and behavioral deficits of prenatally VPA-exposed mice

김현주 2020년
논문상세정보
' Striatal transcriptomic analysis reveals the role of Nurr1 in synaptic and behavioral deficits of prenatally VPA-exposed mice' 의 주제별 논문영향력
논문영향력 선정 방법
논문영향력 요약
주제
  • 의료과학 약
  • Autism spectrum disorder
  • Nurr1
  • Transcriptome
  • rna sequencing
  • striatum
  • synaptic plasticity
  • valproic acid
동일주제 총논문수 논문피인용 총횟수 주제별 논문영향력의 평균
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' Striatal transcriptomic analysis reveals the role of Nurr1 in synaptic and behavioral deficits of prenatally VPA-exposed mice' 의 참고문헌

  • Valproic acid induces aberrant development of striatal compartments and corticostriatal pathways in a mouse model of autism spectrum disorder
    31 ( 10 ) :4458- 71 [2017]
  • Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism
    4.2 [2014]
  • The transgenerational inheritance of autism-like phenotypes in mice exposed to valproic acid during pregnancy
    6:36250 [2016]
  • The role of Nurr1 in the development of dopaminergic neurons and Parkinson 's disease
    77 ( 1-2 ) :128-38 . [2005]
  • The pharmacological stimulation of Nurr1 improves cognitive functions via enhancement of adult hippocampal neurogenesis
    17 ( 3 ) :534-43 . [2016]
  • The cerebral metabolic landscape in autism . Intercorrelations of regional glucose utilization
    45 ( 7 ) :749-55 . [1988]
  • Takahashi T. In Utero Exposure to Valproic Acid Induces Neocortical Dysgenesis via Dysregulation of Neural Progenitor Cell Proliferation/Differentiation
    36 ( 42 ) :10908-19 . [2016]
  • Striatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism
    127 ( 5 ) :1978- 90 [2017]
  • Striatal Transcriptome and Interactome Analysis of Shank3-overexpressing Mice Reveals the Connectivity between Shank3 and mTORC1 Signaling
    0.55625 [2017]
  • Striatal Circuits as a Common Node for Autism Pathophysiology
    0.435416666666667 [2016]
  • Sociability deficits after prenatal exposure to valproic acid are rescued by early social enrichment
    0.4 [2018]
  • Sheng M. Dendritic spines : structure , dynamics and regulation
    2 ( 12 ) :880-8 . [2001]
  • Shen W. D1 and D2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons
    30 ( 5 ) :228- 35 . [2007]
  • Shannon WeickertC. Transcriptomic Analysis Shows DecreasedCortical Expression of NR4A1 , NR4A2 and RXRB in Schizophrenia and Provides Evidence for Nuclear Receptor Dysregulation
    11 ( 12 ) : e0166944 . [2016]
  • Schultz W. The role of the striatum in social behavior
    0.453472222 [2013]
  • Scheiffele P. Distinct Defects in Synaptic Differentiation of Neocortical Neurons in Response to Prenatal Valproate Exposure
    6:27400 [2016]
  • Rare Inherited and De NovoCNVs RevealComplexContributions to ASD Risk in Multiplex Families .
    99 ( 3 ) :540-54 . [2016]
  • Prenatal valproate exposure and risk of autism spectrum disorders andChildhood autism
    309 ( 16 ) :1696-703 . [2013]
  • Nurr1-null heterozygous mice have reduced mesolimbic and mesocortical dopamine levels and increased stress-induced locomotor activity
    136 ( 1 ) :267-75 . [2002]
  • Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons
    95 ( 7 ) :4013-8 . [1998]
  • Nurr1 ( NR4A2 ) regulates Alzheimer 's disease-related pathogenesis and cognitive function in the 5XFAD mouse model
    18 ( 1 ) . [2019]
  • Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson 's disease
    112 ( 28 ) :8756-61 [2015]
  • Nakashima K. Ectopic neurogenesis induced by prenatal antiepileptic drug exposure augments seizure susceptibility in adult mice
    115 ( 16 ) :4270-5 . [2018]
  • NR4A2 haploinsufficiency is associated with intellectual disability and autism spectrum disorder
    94 ( 2 ) :264-8 . [2018]
  • NR4A nuclear receptors support memory enhancement by histone deacetylase inhibitors
    122 ( 10 ) :3593-602 . [2012]
  • Morphological Alterations in the Thalamus , Striatum , and Pallidum in Autism Spectrum Disorder
    41 ( 11 ) :2627-37 . [2016]
  • Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects .
    89 ( 1 ) :147-62 . [2016]
  • Low medial prefrontal dopaminergic activity in autistic children
    350 ( 9078 ) :638 [1997]
  • Li N. Integrated analysis of DNA methylation and RNAsequencing data in Down syndrome
    14 ( 5 ) :4309-14 . [2016]
  • Law PA. Characteristics and concordance of autism spectrum disorders among 277 twin pairs
    163 ( 10 ) :907-14 . [2009]
  • Katsuki H. A Nurr1 agonist amodiaquine attenuates inflammatory events and neurological deficits in a mouse model of intracerebral hemorrhage
    330:48-54 [2019]
  • Identification of Dlk1 , Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neurons
    136 ( 14 ) :2363-73 . [2009]
  • Hikida T. Striatal direct and indirect pathways control decision-making behavior .
    1.111805556 [2014]
  • Genome sequencing identifies multiple deleterious variants in autism patients with more severe phenotypes
    21 ( 7 ) :1611-20 [2019]
  • Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders
    7:10717 [2016]
  • Fetal neural stem cells from a mouse model of 15q11-13 duplication syndrome exhibit altered differentiation into neurons and astrocytes
    139 ( 3 ) :249-53 [2019]
  • Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes
    4 [2019]
  • Effects of rapamycin on social interaction deficits and gene expression in mice exposed to valproic acid in utero
    12 ( 1 ) :3 [2019]
  • Early Behavioral Abnormalities and Perinatal Alterations of PTEN/AKT Pathway in Valproic Acid Autism Model Mice
    11 ( 4 ) : e0153298 . [2016]
  • Durston S. Changes in the development of striatum are involved in repetitive behavior in autism
    76 ( 5 ) :405-11 . [2014]
  • Doya K. Distinct neural representation in the dorsolateral , dorsomedial , and ventral parts of the striatum during fixedand free-choice tasks
    35 ( 8 ) :3499-514 . [2015]
  • Convergent Pathways in Idiopathic Autism Revealed by Time Course Transcriptomic Analysis of Patient-Derived Neurons
    8 ( 1 ) :8423 . [2018]
  • Comparative Gene Expression Analysis of Two Mouse Models of Autism : Transcriptome Profiling of the BTBR and En2 ( -/- ) Hippocampus .
    0.691666667 [2016]
  • Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs .
    360 ( 16 ) :1597-605 . [2009]
  • Chronic Coadministration of nicotine and methamphetamine causes differential expression of immediate early genes in the dorsal striatum and nucleus accumbens of rats
    243:89-96 [2013]
  • Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits .
    19 ( 2 ) :335-50 . [2017]
  • Changes in the developmental trajectories of striatum in autism
    66 ( 4 ) :327-33 . [2009]
  • Brain serotonin and dopamine transporter bindings in adults with high-functioning autism .
    67 ( 1 ) :59-68 . [2010]
  • Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome
    7 ( 4 ) :1077-92 . [2014]
  • Basal ganglia shapes predict social , communication , and motor dysfunctions in boys with autism spectrum disorder
    49 ( 6 ) :539-51 , 51 e1-4 [2010]
  • Bao W. Prevalence of Autism Spectrum Disorder Among US Children and Adolescents , 2014-2016
    319 ( 1 ) :81-2 . [2018]
  • Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors
    158 ( 1 ) :198-212 . [2014]
  • Adult mice with reduced Nurr1 expression : an animal model for schizophrenia
    12 ( 8 ) :756-66 . [2007]
  • Aberrant striatal functional connectivity in children with autism
    69 ( 9 ) :847-56 [2011]
  • A Corticostriatal Path Targeting Striosomes Controls Decision-Making under Conflict
    161 ( 6 ) :1320-33 . [2015]