박사

Rev-erbα 조절물질 발굴과 도파민 보상 회로에서의 일주기 기능에 관한 연구 = Studies on identification of Rev-erbα modulator by cell-based assay and its circadian action on dopamine reward pathway

이지연 2016년
논문상세정보
' Rev-erbα 조절물질 발굴과 도파민 보상 회로에서의 일주기 기능에 관한 연구 = Studies on identification of Rev-erbα modulator by cell-based assay and its circadian action on dopamine reward pathway' 의 주제별 논문영향력
논문영향력 선정 방법
논문영향력 요약
주제
  • 생활과학
  • Circadian clock
  • Nurr1
  • Rev-erbα
  • Sucrose
  • dopamine(da)
  • reward
  • small molecule
동일주제 총논문수 논문피인용 총횟수 주제별 논문영향력의 평균
1,656 0

0.0%

' Rev-erbα 조절물질 발굴과 도파민 보상 회로에서의 일주기 기능에 관한 연구 = Studies on identification of Rev-erbα modulator by cell-based assay and its circadian action on dopamine reward pathway' 의 참고문헌

  • Yin L, Wu N, Curtin JC, Qatanani M, Szwergold NR, Reid RA, Waitt GM, Parks DJ, Pearce KH, Wisely GB., and Lazar MA. (2007) Rev-erb alpha, a heme sensor that coordinates metabolic and circadian pathways. Science. 318, 1786-9.
  • Yin L, Wang J, Klein PS., and Lazar MA. (2006) Nuclear receptor Rev-erb alpha is a critical lithium-sensitive component of the circadian clock. Science. 311, 1002-5.
  • Yin L, Joshi S, Wu N, Tong X., and Lazar MA. (2010) E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha. Proc Natl Acad Sci U S A. 107, 11614-9.
  • Yasoshima Y and Shimura T. (2015) A mouse model for binge-like sucrose overconsumption: Contribution of enhanced motivation for sweetener consumption. Physiol Behav. 138, 154-64.
  • Yagita K, Tamanini F, van Der Horst GT, and Okamura H. (2001) Molecular mechanisms of the biological clock in cultured fibroblasts. Science. 292, 278-81.
  • Woldt E, Sebti Y, Solt LA, Duhem C, Lancel S, Eeckhoute J, Hesselink MK, Paquet C, Delhaye S, Shin Y, Kamenecka TM, Schaart G, Lefebvre P, Nevi re R, Burris TP, Schrauwen P, Staels B., and Duez H. (2013) Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy. Nat Med. 19, 1039-46.
  • Willson TM, and Zuercher WJ. (2010) GSK4112, a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα. ACS Chem Biol. 5, 925-32.
  • Wideman CH, Nadzam GR, and Murphy HM. (2005) Implications of an animal model of sugar addiction, withdrawal and relapse for human health. Nutr Neurosci. 8, 269-76.
  • Welsh DK, Takahashi JS., and Kay SA. (2010) Suprachiasmatic nucleus: cell autonomy and network properties. Annu Rev Physiol. 72, 551-77.
  • Wang Y, Kumar N, Nuhant P, Cameron MD, Istrate MA, Roush WR, Griffin PR., and Burris TP. (2010) Identification of SR1078, a synthetic agonist for the orphan nuclear receptors RORα and RORγ. ACS Chem Biol. 5, 1029–1034.
  • Wang J, Yin L., and Lazar MA. (2006) The orphan nuclear receptor Rev-erb alpha regulates circadian expression of plasminogen activator inhibitor type 1. J Biol Chem. 281, 33842-8.
  • Volkow ND and Morales M. (2015) The Brain on Drugs: From Reward to Addiction. Cell. 162, 712-25.
  • Uyeda K and Repa JJ. (2006) Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis. Cell Metab. 4, 107-10.
  • Trump RP, Bresciani S, Cooper AW, Tellam JP, Wojno J, Blaikley J, Orband- Miller LA, Kashatus JA, Boudjelal M, Dawson HC, Loudon A, Ray D, Grant D, Farrow SN, Willson TM., and Tomkinson NC. (2013) Optimized chemical probes for REV-ERBα. J Med Chem. 56, 4729-37.
  • Trinko R, Sears RM, Guarnieri DJ, and DiLeone RJ. (2007) Neural mechanisms underlying obesity and drug addiction. Physiol Behav. 91, 499-505.
  • Teli MR, James OF, Burt AD, Bennett MK, and Day CP. (1995) The natural history of nonalcoholic fatty liver: a follow-up study. Hepatology. 22, 1714-9.
  • Tanofsky-Kraff M, Cohen ML, Yanovski SZ, Cox C, Theim KR, Keil M, Reynolds JC, and Yanovski JA. (2006) A prospective study of psychological predictors of body fat gain among children at high risk for adult obesity. Pediatrics. 117, 1203-9.
  • Takahashi JS. (2015) Molecular components of the circadian clock in mammals. Diabetes Obes Metab. 1, 6-11.
  • Suzuki T, Yamakuni T, Hagiwara M, Ichinose H. Identification of ATF-2 as a transcriptional regulator for the tyrosine hydroxylase gene. J Biol Chem. 277, 40768-74.
  • Stratmann M, Schibler U. (2006) Properties, entrainment, and physiological functions of mammalian peripheral oscillators. J Biol Rhythms. 21, 494- 506.
  • Spencer S, Falcon E, Kumar J, Krishnan V, Mukherjee S, Birnbaum SG, and McClung CA. (2013) Circadian genes Period 1 and Period 2 in the nucleus accumbens regulate anxiety-related behavior. Eur J Neurosci. 37, 242-50.
  • Son GH, Chung S, Choe HK, Kim HD, Baik SM, Lee H, Lee HW, Choi S, Sun W, Kim H, Cho S, Lee KH, and Kim K. (2008) Adrenal peripheral clock controls the autonomous circadian rhythm of glucocorticoid by causing rhythmic steroid production. Proc Natl Acad Sci U S A. 105, 20970-5.
  • Solt LA, Wang Y, Banerjee S, Hughes T, Kojetin DJ, Lundasen T, Shin Y, Liu J, Cameron MD, Noel R, Yoo SH, Takahashi JS, Butler AA, Kamenecka TM., and Burris TP. (2012) Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature. 485, 62-8.
  • Smith Y and Kieval JZ. (2000) Anatomy of the dopamine system in the basal ganglia. Trends Neurosci. 23, S28-33.
  • Sitaula S, Billon C, Kamenecka TM, Solt LA, Burris TP. (2015) Suppression of atherosclerosis by synthetic REV-ERB agonist. Biochem Biophys Res Commun. 460, 566-71.
  • Sato TK, Panda S, Miraglia LJ, Reyes TM, Rudic RD, McNamara P, Naik KA, FitzGerald GA, Kay SA., and Hogenesch JB. (2004) A functional genomics strategy reveals Ror alpha as a component of the mammalian circadian clock. Neuron. 43, 527-37.
  • Sato S, Sakurai T, Ogasawara J, Shirato K, Ishibashi Y, Oh-ishi S, Imaizumi K, Haga S, Hitomi Y, Izawa T, Ohira Y, Ohno H, and Kizaki T. (2014) Direct and indirect suppression of interleukin-6 gene expression in murine macrophages by nuclear orphan receptor REV-ERBα. ScientificWorldJournal. 2014, 685854.
  • Sahar S, Zocchi L, Kinoshita C, Borrelli E., and Sassone-Corsi P. (2010) Regulation of BMAL1 protein stability and circadian function by GSK3 beta-mediated phosphorylation. PLoS One. 5, e8561.
  • Ruano EG, Canivell S, and Vieira E. (2014) REV-ERB ALPHA polymorphism is associated with obesity in the Spanish obese male population. PLoS One. 9, e104065.
  • Ripperger JA and Albrecht U. (2012) REV-ERB-erating nuclear receptor functions in circadian metabolism and physiology. Cell Res. 22, 1319- 21.
  • Ramakrishnan SN, Lau P, Crowther LM, Cleasby ME, Millard S, Leong GM, Cooney GJ, and Muscat GE. (2009) Rev-erb beta regulates the Srebp- 1c promoter and mRNA expression in skeletal muscle cells. Biochem Biophys Res Commun. 388, 654-9.
  • Rada P, Avena NM, and Hoebel BG. (2005) Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell. Neuroscience. 134, 737-44.
  • Ponsalle P, Srivastava LS, Uht RM, and White JD. (1992) Glucocorticoids are Required for Food Deprivation-Induced Increases in Hypothalamic Neuropeptide Y Expression. J Neuroendocrinol. 4, 585-91.
  • Partch CL, Green CB., and Takahashi JS (2014) Molecular architecture of the mammalian circadian clock. Trends Cell Biol. 24, 90-9.
  • Osland TM, Fern J, H vik B, Heuch I, Ruoff P, L rum OD., and Steen VM. (2011) Lithium differentially affects clock gene expression in serumshocked NIH-3T3 cells. J Psychopharmacol. 25, 924-33.
  • Nestler EJ, Barrot M, and Self DW. (2001) DeltaFosB: a sustained molecular switch for addiction. Proc Natl Acad Sci U S A. 98, 11042-6.
  • Negoro H, Okinami T, Kanematsu A, Imamura M, Tabata Y., and Ogawa O. (2013) Role of Rev-erbα domains for transactivation of the connexin43 promoter with Sp1. FEBS Lett. 587, 98-103.
  • Nangle SN, Rosensweig C, Koike N, Tei H, Takahashi JS, Green CB., and Zheng N. (2014) Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex. Elife. 3, e03674.
  • Mohawk JA, Green CB., and Takahashi JS. (2012) Central and peripheral circadian clocks in mammals. Annu Rev Neurosci. 35, 445-62.
  • McClung CA. (2007) Circadian rhythms, the mesolimbic dopaminergic circuit, and drug addiction. ScientificWorldJournal. 7, 194-202
  • McClung CA, Sidiropoulou K, Vitaterna M, Takahashi JS, White FJ, Cooper DC, and Nestler EJ. (2005) Regulation of dopaminergic transmission and cocaine reward by the Clock gene. Proc Natl Acad Sci U S A. 102, 9377-81.
  • Luo Z, Volkow ND, Heintz N, Pan Y, and Du C. (2011) Acute cocaine induces fast activation of D1 receptor and progressive deactivation of D2 receptor striatal neurons: in vivo optical microprobe [Ca2+]i imaging. J Neurosci. 31, 13180-90.
  • Liu C, Li S, Liu T, Borjigin J., and Lin JD. (2007) Transcriptional coactivator PGC-1 alpha integrates the mammalian clock and energy metabolism. Nature. 447, 477-81.
  • Liu AC, Tran HG, Zhang EE, Priest AA, Welsh DK., and Kay SA. (2008) Redundant function of REV-ERB alpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms. PLoS Genet. 4, e1000023.
  • Li J, Lu WQ, Beesley S, Loudon AS., and Meng QJ. (2012) Lithium impacts on the amplitude and period of the molecular circadian clockwork. PLoS One. 7, e33292.
  • Lewis SR, Ahmed S, Dym C, Khaimova E, Kest B, and Bodnar RJ. (2005) Inbred mouse strain survey of sucrose intake. Physiol Behav. 85, 546- 56.
  • Levi F and Schibler U. (2007) Circadian rhythms: mechanisms and therapeutic implications. Annu Rev Pharmacol Toxicol. 47, 593-628.
  • Lee J, Lee Y, Lee MJ, Park E, Kang SH, Chung CH, Lee KH., and Kim K. (2008) Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex. Mol Cell Biol. 28, 6056-65.
  • Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, Tanaka-Oishi Y, Benner C, Kaikkonen MU, Kim AS, Kosaka M, Lee CY, Watt A, Grossman TR, Rosenfeld MG, Evans RM, and Glass CK. (2013) Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature. 498, 511-5.
  • Laitinen S, Fontaine C, Fruchart JC, and Staels B. (2005) The role of the orphan nuclear receptor Rev-Erb alpha in adipocyte differentiation and function. Biochimie. 87, 21-5.
  • Kwon I, Lee J, Chang SH, Jung NC, Lee BJ, Son GH, Kim K., and Lee KH. (2006) BMAL1 shuttling controls transactivation and degradation of the CLOCK/BMAL1 heterodimer. Mol Cell Biol. 26, 7318-30.
  • Kumar N, Solt LA, Wang Y, Rogers PM, Bhattacharyya G, Kamenecka TM, Stayrook KR, Crumbley C, Floyd ZE, Gimble JM, Griffin PR., and Burris TP. (2010) Regulation of adipogenesis by natural and synthetic REV-ERB ligands. Endocrinology. 151, 3015-25.
  • Koo J, Choe HK, Kim HD, Chun SK, Son GH., and Kim K. (Dec 9, 2014) Effect of Mefloquine, a Gap Junction Blocker, on Circadian Period2 Gene Oscillation in the Mouse Suprachiasmatic Nucleus Ex Vivo. Endocrinol Metab. [Epub ahead of print]
  • Kojetin DJ and Burris TP. (2014) REV-ERB and ROR nuclear receptors as drug targets. Nat Rev Drug Discov. 13, 197-216.
  • Kojetin D, Wang Y, Kamenecka TM., and Burris TP. (2011) Identification of SR8278, a synthetic antagonist of the nuclear heme receptor REVERB. ACS Chem Biol. 6, 131-4.
  • John PC, Hirota T, Kay SA., and Doyle FJ. (2014) Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock. Proc Natl Acad Sci U S A. 111, 2040-5.
  • Jeong K, He B, Nohara K, Park N, Shin Y, Kim S, Shimomura K, Koike N, Yoo SH, and Chen Z. (2015) Dual attenuation of proteasomal and autophagic BMAL1 degradation in Clock Δ19/+ mice contributes to improved glucose homeostasis. Sci Rep. 5, 12801.
  • Janevski M, Ratnayake S, Siljanovski S, McGlynn MA, Cameron-Smith D, and Lewandowski P. (2012) Fructose containing sugars modulate mRNA of lipogenic genes ACC and FAS and protein levels of transcription factors ChREBP and SREBP1c with no effect on body weight or liver fat. Food Funct. 3, 141-9.
  • Hu FB and Malik VS. (2010) Sugar-sweetened beverages and risk of obesity and type 2 diabetes: epidemiologic evidence. Physiol Behav. 100, 47-54.
  • Hone-Blanchet A and Fecteau S. (2014) Overlap of food addiction and substance use disorders definitions: analysis of animal and human studies. Neuropharmacology. 85, 81-90.
  • Hoebel BG, Avena NM, Bocarsly ME, and Rada P. (2009) Natural addiction: a behavioral and circuit model based on sugar addiction in rats. J Addict Med. 3:33-4.
  • Hirayama J, Sahar S, Grimaldi B, Tamaru T, Takamatsu K, Nakahata Y., and Sassone-Corsi P. (2007) CLOCK-mediated acetylation of BMAL1 controls circadian function. Nature. 450, 1086-90.
  • Harding HP and Lazar MA. (1993) The orphan receptor Rev-ErbA alpha activates transcription via a novel response element. Cell Biol. 13, 3113-21.
  • Hampp G, Ripperger JA, Houben T, Schmutz I, Blex C, Perreau-Lenz S, Brunk I, Spanagel R, Ahnert-Hilger G, Meijer JH, and Albrecht U. (2008) Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood. Curr Biol. 18, 678-83.
  • Gustafson CL and Partch CL. (2015) Emerging models for the molecular basis of mammalian circadian timing. Biochemistry. 54, 134-49.
  • Grant D, Yin L, Collins JL, Parks DJ, Orband-Miller LA, Wisely GB, Joshi S, Lazar MA, Willson TM., and Zuercher WJ. (2010) GSK4112, a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα. ACS Chem Biol. 5, 925-32.
  • Gr chez-Cassiau A, Feillet C, Gu rin S, and Delaunay F. (2015) The hepatic circadian clock regulates the choline kinase α gene through the BMAL1-REV-ERBα axis. Chronobiol Int. 32, 774-84.
  • Giros B, Jaber M, Jones SR, Wightman RM, and Caron MG. (1996) Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature. 379, 606-12.
  • Falcon E, Ozburn A, Mukherjee S, Roybal K, and McClung CA. (2013) Differential regulation of the period genes in striatal regions following cocaine exposure. PLoS One. 8, e66438.
  • Everett LJ and Lazar MA. (2014) Nuclear receptor Rev-erbα: up, down, and all around. Trends Endocrinol Metab. 25, 586-92.
  • Duez H, Staels B. (2009) Rev-erb-alpha: an integrator of circadian rhythms and metabolism. J Appl Physiol. 107, 1972-80.
  • Dibner C, Schibler U., and Albrecht U. (2010) The mammalian circadian timing system: organization and coordination of central and peripheral clocks. Annu Rev Physiol. 72, 517-49.
  • Davis CA, Levitan RD, Reid C, Carter JC, Kaplan AS, Patte KA, King N, Curtis C, and Kennedy JL. (2009) Dopamine for "wanting" and opioids for "liking": a comparison of obese adults with and without binge eating. Obesity (Silver Spring). 17, 1220-5.
  • Davis C and Claridge G. (1998) The eating disorders as addiction: a psychobiological perspective. Addict Behav. 23, 463-75.
  • Crumbley C, Wang Y, Banerjee S., and Burris TP. (2012) Regulation of expression of citrate synthase by the retinoic acid receptor-related orphan receptor α (RORα). PLoS One. 7, e33804.
  • Colantuoni C, Rada P, McCarthy J, Patten C, Avena NM, Chadeayne A, and Hoebel BG. (2002) Evidence that intermittent, excessive sugar intake causes endogenous opioid dependence. Obes Res. 10, 478-88.
  • Chung S, Lee EJ, Yun S, Choe HK, Park SB, Son HJ, Kim KS, Dluzen DE, Lee I, Hwang O, Son GH, Kim K. (2014) Impact of circadian nuclear receptor REV-ERBα on midbrain dopamine production and mood regulation. Cell. 157, 858-68.
  • Chun SK, Jang J, Chung S, Yun H, Kim NJ, Jung JW, Son GH, Suh YG., and Kim K. (2014) Identification and validation of cryptochrome inhibitors that modulate the molecular circadian clock. ACS Chem Biol. 9, 703-10.
  • Cho H, Zhao X, Hatori M, Yu RT, Barish GD, Lam MT, Chong LW, DiTacchio L, Atkins AR, Glass CK, Liddle C, Auwerx J, Downes M, Panda S., and Evans RM. (2012) Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β. Nature. 485, 123-7.
  • Cheon S, Park N, Cho S., and Kim K. (2013) Glucocorticoid-mediated Period2 induction delays the phase of circadian rhythm. Nucleic Acids Res. 41, 6161-74.
  • Challet E, Caldelas I, Graff C, and P vet P. (2003) Synchronization of the molecular clockwork by light- and food-related cues in mammals. Biol Chem. 384, 711-9.
  • Bundel D, Gangarossa G, Biever A, Bonnefont X, and Valjent E. (2013) Cognitive dysfunction, elevated anxiety, and reduced cocaine response in circadian clock-deficient cryptochrome knockout mice. Front Behav Neurosci. 7, 152.
  • Bray GA, Paeratakul S, and Popkin BM. (2004) Dietary fat and obesity: a review of animal, clinical and epidemiological studies. Physiol Behav. 83, 549-55.
  • Bollinger T and Schibler U. (2014) Circadian rhythms - from genes to physiology and disease. Swiss Med Wkly. 144, w13984.
  • Bechtold DA, Gibbs JE, and Loudon AS. (2010) Circadian dysfunction in disease. Trends Pharmacol Sci. 31, 191-8.
  • Baptista MJ, O'Farrell C, Daya S, Ahmad R, Miller DW, Hardy J, Farrer MJ, Cookson MR. (2003) Co-ordinate transcriptional regulation of dopamine synthesis genes by alpha-synuclein in human neuroblastoma cell lines. J Neurochem. 85, 957-68.
  • Banerjee S, Wang Y, Solt LA, Griffett K, Kazantzis M, Amador A, El-Gendy BM, Huitron-Resendiz S, Roberts AJ, Shin Y, Kamenecka TM., and Burris TP. (2014) Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour. Nat Commun. 5, 5759.
  • Balsalobre A, Damiola F, and Schibler U. (1998) A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell. 93, 929-37.
  • Avena NM, Rada P, and Hoebel BG. (2009) Sugar and fat bingeing have notable differences in addictive-like behavior. J Nutr. 139, 623-8.
  • Avena NM, Rada P, and Hoebel BG. (2008) Evidence for sugar addiction: behavioral and neurochemical effects of intermittent, excessive sugar intake. Neurosci Biobehav Rev. 32, 20-39.
  • Avena NM, Rada P, Moise N, and Hoebel BG. (2006) Sucrose sham feeding on a binge schedule releases accumbens dopamine repeatedly and eliminates the acetylcholine satiety response. Neuroscience. 139, 813-20.
  • Avena NM, Bocarsly ME, Rada P, Kim A, and Hoebel BG. (2008) After daily bingeing on a sucrose solution, food deprivation induces anxiety and accumbens dopamine/acetylcholine imbalance. Physiol Behav. 94, 309-15.
  • Aumann TD, Egan K, Lim J, Boon WC, Bye CR, Chua HK, Baban N, Parish CL, Bobrovskaya L, Dickson P, Horne MK. (2011) Neuronal activity regulates expression of tyrosine hydroxylase in adult mouse substantia nigra pars compacta neurons. J Neurochem. 116, 646-58.
  • Arias-Carri n O, Stamelou M, Murillo-Rodr guez E, Men ndez-Gonz lez M, and P ppel E. (2010) Dopaminergic reward system: a short integrative review. Int Arch Med. 3, 24.
  • Albus H, Bonnefont X, Chaves I, Yasui A, Doczy J, van der Horst GT, Meijer JH. (2002) Cryptochrome-deficient mice lack circadian electrical activity in the suprachiasmatic nuclei. Curr Biol. 12, 1130-3.
  • Abarca C, Albrecht U, and Spanagel R. (2002) Cocaine sensitization and reward are under the influence of circadian genes and rhythm. Proc Natl Acad Sci U S A. 99, 9026-30.