박사

2i 조건에서 Jmjd2c와 Prdm14를 통한 생쥐배아줄기세포의 stemness 유지에 관한 연구 = The maintenance of mouse embryonic stem cell stemness through Jmjd2c and Prdm14 in 2i condition

심예지 2016년
논문상세정보
    • 저자 심예지
    • 형태사항 삽도: 26 cm: iii, 50 p.
    • 일반주기 지도교수: 김계성, 권두 Abstract, 권말 국문요지 수록, 참고문헌: p. 44-48
    • 학위논문사항 의생명공학과, 한양대학교 대학원, 2016. 2, 학위논문(박사)-
    • 발행지 서울
    • 언어 eng
    • 출판년 2016
    • 발행사항 한양대학교 대학원
    • 주제어 의용생체공학
    유사주제 논문( 18)
' 2i 조건에서 Jmjd2c와 Prdm14를 통한 생쥐배아줄기세포의 stemness 유지에 관한 연구 = The maintenance of mouse embryonic stem cell stemness through Jmjd2c and Prdm14 in 2i condition' 의 주제별 논문영향력
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동일주제 총논문수 논문피인용 총횟수 주제별 논문영향력의 평균
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' 2i 조건에서 Jmjd2c와 Prdm14를 통한 생쥐배아줄기세포의 stemness 유지에 관한 연구 = The maintenance of mouse embryonic stem cell stemness through Jmjd2c and Prdm14 in 2i condition' 의 참고문헌

  • Z.D. Smith, M.M. Chan, T.S. Mikkelsen, H. Gu, A. Gnirke, A. Regev, A. Meissner, A unique regulatory phase of DNA methylation in the early mammalian embryo, Nature, 484 (2012) 339-344.
  • Y.H. Loh, W. Zhang, X. Chen, J. George, H.H. Ng, Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells, Genes Dev, 21 (2007) 2545-2557.
  • Y. Kawahara, T. Manabe, M. Matsumoto, T. Kajiume, M. Matsumoto, L. Yuge, LIF-free embryonic stem cell culture in simulated microgravity, PLoS One, 4 (2009) e6343.
  • X. Zhang, K.A. Peterson, X.S. Liu, A.P. McMahon, S. Ohba, Gene regulatory networks mediating canonical Wnt signal-directed control of pluripotency and differentiation in embryo stem cells, Stem Cells, 31 (2013) 2667-2679.
  • V.W. Zhou, A. Goren, B.E. Bernstein, Charting histone modifications and the functional organization of mammalian genomes, Nat Rev Genet, 12 (2011) 7- 18.
  • T.P. Gu, F. Guo, H. Yang, H.P. Wu, G.F. Xu, W. Liu, Z.G. Xie, L. Shi, X. He, S.G. Jin, K. Iqbal, Y.G. Shi, Z. Deng, P.E. Szabo, G.P. Pfeifer, J. Li, G.L. Xu, The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes, Nature, 477 (2011) 606-610.
  • T. Kunath, M.K. Saba-El-Leil, M. Almousailleakh, J. Wray, S. Meloche, A. Smith, FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment, Development, 134 (2007) 2895-2902.
  • S. Seisenberger, S. Andrews, F. Krueger, J. Arand, J. Walter, F. Santos, C. Popp, B. Thienpont, W. Dean, W. Reik, The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells, Mol Cell, 48 (2012) 849-862.
  • S. Ito, A.C. D'Alessio, O.V. Taranova, K. Hong, L.C. Sowers, Y. Zhang, Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification, Nature, 466 (2010) 1129-1133.
  • Q.L. Ying, J. Wray, J. Nichols, L. Batlle-Morera, B. Doble, J. Woodgett, P. Cohen, A. Smith, The ground state of embryonic stem cell self-renewal, Nature, 453 (2008) 519-523.
  • Q.L. Ying, J. Nichols, I. Chambers, A. Smith, BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3, Cell, 115 (2003) 281-292.
  • P.P. Das, Z. Shao, S. Beyaz, E. Apostolou, L. Pinello, A. De Los Angeles, K. O'Brien, J.M. Atsma, Y. Fujiwara, M. Nguyen, D. Ljuboja, G. Guo, A. Woo, G.C. Yuan, T. Onder, G. Daley, K. Hochedlinger, J. Kim, S.H. Orkin, Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity, Mol Cell, 53 (2014) 32-48.
  • N.Y. Chia, Y.S. Chan, B. Feng, X. Lu, Y.L. Orlov, D. Moreau, P. Kumar, L. Yang, J. Jiang, M.S. Lau, M. Huss, B.S. Soh, P. Kraus, P. Li, T. Lufkin, B. Lim, N.D. Clarke, F. Bard, H.H. Ng, A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity, Nature, 468 (2010) 316- 320.
  • N. Grabole, J. Tischler, J.A. Hackett, S. Kim, F. Tang, H.G. Leitch, E. Magnusdottir, M.A. Surani, Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation, EMBO Rep, 14 (2013) 629-637.
  • M.T. Pedersen, K. Agger, A. Laugesen, J.V. Johansen, P.A. Cloos, J. Christensen, K. Helin, The demethylase JMJD2C localizes to H3K4me3- positive transcription start sites and is dispensable for embryonic development, Mol Cell Biol, 34 (2014) 1031-1045.
  • M.P. Stavridis, J.S. Lunn, B.J. Collins, K.G. Storey, A discrete period of FGFinduced Erk1/2 signalling is required for vertebrate neural specification, Development, 134 (2007) 2889-2894.
  • M.J. Evans, M.H. Kaufman, Establishment in culture of pluripotential cells from mouse embryos, Nature, 292 (1981) 154-156.
  • M. Yamaji, Y. Seki, K. Kurimoto, Y. Yabuta, M. Yuasa, M. Shigeta, K. Yamanaka, Y. Ohinata, M. Saitou, Critical function of Prdm14 for the establishment of the germ cell lineage in mice, Nat Genet, 40 (2008) 1016- 1022.
  • M. Yamaji, J. Ueda, K. Hayashi, H. Ohta, Y. Yabuta, K. Kurimoto, R. Nakato, Y. Yamada, K. Shirahige, M. Saitou, PRDM14 ensures naive pluripotency through dual regulation of signaling and epigenetic pathways in mouse embryonic stem cells, Cell Stem Cell, 12 (2013) 368-382.
  • M. Tahiliani, K.P. Koh, Y. Shen, W.A. Pastor, H. Bandukwala, Y. Brudno, S. Agarwal, L.M. Iyer, D.R. Liu, L. Aravind, A. Rao, Conversion of 5- methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1, Science, 324 (2009) 930-935.
  • M. Tachibana, K. Sugimoto, T. Fukushima, Y. Shinkai, Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3, J Biol Chem, 276 (2001) 25309-25317.
  • L. Aghajanova, Leukemia inhibitory factor and human embryo implantation, Ann N Y Acad Sci, 1034 (2004) 176-183.
  • K.B. Dong, I.A. Maksakova, F. Mohn, D. Leung, R. Appanah, S. Lee, H.W. Yang, L.L. Lam, D.L. Mager, D. Schubeler, M. Tachibana, Y. Shinkai, M.C. Lorincz, DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity, EMBO J, 27 (2008) 2691-2701.
  • J.U. Guo, Y. Su, C. Zhong, G.L. Ming, H. Song, Hydroxylation of 5- methylcytosine by TET1 promotes active DNA demethylation in the adult brain, Cell, 145 (2011) 423-434.
  • J.A. Hackett, R. Sengupta, J.J. Zylicz, K. Murakami, C. Lee, T.A. Down, M.A. Surani, Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine, Science, 339 (2013) 448-452.
  • J. Wray, T. Kalkan, A.G. Smith, The ground state of pluripotency, Biochem Soc Trans, 38 (2010) 1027-1032.
  • J. Wang, M. Zhang, Y. Zhang, Z. Kou, Z. Han, D.Y. Chen, Q.Y. Sun, S. Gao, The histone demethylase JMJD2C is stage-specifically expressed in preimplantation mouse embryos and is required for embryonic development, Biol Reprod, 82 (2010) 105-111.
  • J. Nichols, J. Silva, M. Roode, A. Smith, Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo, Development, 136 (2009) 3215-3222.
  • J. Nichols, A. Smith, The origin and identity of embryonic stem cells, Development, 138 (2011) 3-8.
  • J. Chen, H. Liu, J. Liu, J. Qi, B. Wei, J. Yang, H. Liang, Y. Chen, J. Chen, Y. Wu, L. Guo, J. Zhu, X. Zhao, T. Peng, Y. Zhang, S. Chen, X. Li, D. Li, T. Wang, D. Pei, H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs, Nat Genet, 45 (2013) 34-42.
  • H.H. Ng, M.A. Surani, The transcriptional and signalling networks of pluripotency, Nat Cell Biol, 13 (2011) 490-496.
  • H.G. Leitch, K.R. McEwen, A. Turp, V. Encheva, T. Carroll, N. Grabole, W. Mansfield, B. Nashun, J.G. Knezovich, A. Smith, M.A. Surani, P. Hajkova, Naive pluripotency is associated with global DNA hypomethylation, Nat Struct Mol Biol, 20 (2013) 311-316.
  • H. Wu, Y. Zhang, Mechanisms and functions of Tet protein-mediated 5- methylcytosine oxidation, Genes Dev, 25 (2011) 2436-2452.
  • H. Marks, T. Kalkan, R. Menafra, S. Denissov, K. Jones, H. Hofemeister, J. Nichols, A. Kranz, A.F. Stewart, A. Smith, H.G. Stunnenberg, The transcriptional and epigenomic foundations of ground state pluripotency, Cell, 149 (2012) 590-604.
  • H. Bagci, A.G. Fisher, DNA demethylation in pluripotency and reprogramming: the role of tet proteins and cell division, Cell Stem Cell, 13 (2013) 265-269.
  • G.R. Martin, Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells, Proc Natl Acad Sci U S A, 78 (1981) 7634-7638.
  • F. Nakaki, M. Saitou, PRDM14: a unique regulator for pluripotency and epigenetic reprogramming, Trends Biochem Sci, 39 (2014) 289-298.
  • E.S. Jung, Y.J. Sim, H.S. Jeong, S.J. Kim, Y.J. Yun, J.H. Song, S.H. Jeon, C. Choe, K.T. Park, C.H. Kim, K.S. Kim, Jmjd2C increases MyoD transcriptional activity through inhibiting G9a-dependent MyoD degradation, Biochim Biophys Acta, 1849 (2015) 1081-1094.
  • E. Meshorer, T. Misteli, Chromatin in pluripotent embryonic stem cells and differentiation, Nat Rev Mol Cell Biol, 7 (2006) 540-546.
  • D.M. Owens, S.M. Keyse, Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases, Oncogene, 26 (2007) 3203-3213.
  • D. Balasubramanian, B. Akhtar-Zaidi, L. Song, C.F. Bartels, M. Veigl, L. Beard, L. Myeroff, K. Guda, J. Lutterbaugh, J. Willis, G.E. Crawford, S.D. Markowitz, P.C. Scacheri, H3K4me3 inversely correlates with DNA methylation at a large class of non-CpG-island-containing start sites, Genome Med, 4 (2012) 47.
  • C.K. Fog, G.G. Galli, A.H. Lund, PRDM proteins: important players in differentiation and disease, Bioessays, 34 (2012) 50-60.
  • A. Bradley, M. Evans, M.H. Kaufman, E. Robertson, Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines, Nature, 309 (1984) 255-256.
  • A. Bird, DNA methylation patterns and epigenetic memory, Genes Dev, 16 (2002) 6-21.