연구동향 분석
박사

신경세포 시냅스의 구조적 기능적 가소성에 대한 분자 기전

오준영 2015년

논문상세정보
인용/피인용
' 신경세포 시냅스의 구조적 기능적 가소성에 대한 분자 기전' 의 주제별 논문영향력
논문영향력 선정 방법
논문영향력 요약
주제
  • actin cytoskeleton
  • local protein synthesis
  • synaptic plasticity
동일주제 총논문수 논문피인용 총횟수 주제별 논문영향력의 평균
36 0

0.0%

' 신경세포 시냅스의 구조적 기능적 가소성에 대한 분자 기전' 의 참고문헌

  • van Galen,E.J.,andRamakers,G.J(2005),"Rhoproteins,mentalretardationand the neurobiological basis of intelligence," Progress in brainresearch,147,295-317.
  • van Bokhoven, H(2011), "Genetic and epigenetic networks in intellectualdisabilities,"Annualreview ofgenetics,45,81-104.
  • Zhou,F.Q.,and Snider,W.D(2006),"Intracellularcontrolofdevelopmentaland regenerative axon growth," Philosophical Transactions of theRoyalSocietyB:BiologicalSciences,361,1575-1592.
  • Zhang,Z.,Chen,L.,Gao,L.,Lin,K.,Zhu,L.,Lu,Y.,Shi,X.,Gao,Y.,Zhou,J.,and Xu,P(2012),"Structuralbasis forthe recognition ofAsefbyadenomatouspolyposiscoli,"Cellresearch,22,372-386.
  • Zhang,H.,Webb,D.J.,Asmussen,H.,and Horwitz,A.F(2003),"Synapseformationisregulatedbythesignaling adaptorGIT1,"TheJournalofcellbiology,161,131-142.
  • Zhang,H.,Webb,D.J.,Asmussen,H.,Niu,S.,and Horwitz,A.F(2005),"AGIT1/PIX/Rac/PAK signaling module regulates spine morphogenesisand synapse formation through MLC," The Journalofneuroscience,25,3379-3388.
  • Zeitelhofer,M.,Macchi,P.,and Dahm,R(2008a),"Perplexing bodies: theputativerolesofP-bodiesinneurons,"RNA biology,5,244-248.
  • Zeitelhofer,M.,Karra,D.,Macchi,P.,Tolino,M.,Thomas,S.,Schwarz,M.,Kiebler, M., and Dahm, R(2008b), "Dynamic interaction betweenP-bodies and transport ribonucleoprotein particles in dendrites ofmature hippocampal neurons," The Journal of Neuroscience, 28,7555-7562.
  • Yoshihara,Y.,De Roo,M.,and Muller,D(2009),"Dendritic spine formationandstabilization,"Currentopinioninneurobiology,19,146-153.
  • Xie,Z.,Srivastava,D.P.,Photowala,H.,Kai,L.,Cahill,M.E.,Woolfrey,K. M.,Shum,C,Y.,Surmeier,D,J., and Penzes,P(2007),"Kalirin-7controls activity-dependent structural and functional plasticity ofdendriticspines,"Neuron,56,640-656.
  • Xie,Z.,Photowala,H.,Cahill,M.E.,Srivastava,D.P.,Woolfrey,K.M.,Shum,C.Y.,Huganir,R,L.,and Penzes,P(2008),"Coordination ofsynaptic adhesion with dendritic spine remodeling by AF-6 andkalirin-7,"TheJournalofNeuroscience,28,6079-6091.
  • Wilczynska,A.,Aigueperse,C.,Kress,M.,Dautry,F.,and Weil,D(2005),"The translational regulator CPEB1 provides a link between dcp1bodiesandstressgranules,"Journalofcellscience,118,981-992.
  • Wickham,L.,Duchaine,T.,Luo,M.,Nabi,I.R.,and DesGroseillers,L(1999),"Mammalian staufen is a double-stranded-RNA and tubulin-bindingproteinwhichlocalizestotheroughendoplasmicreticulum,"Molecularandcellularbiology,19,2220-2230.
  • Whitehead,I.P.,Campbell,S.,Rossman,K.L.,and Der,C.J(1997),"Dblfamily proteins," Biochimica etBiophysica Acta (BBA)-Reviews onCancer,1332,F1-F23.
  • Wennerberg,K.,andDer,C.J(2004),"Rho-familyGTPases:it'snotonlyRacandRho(andIlikeit),"Journalofcellscience,117,1301-1312.
  • Washbourne,P.,Dityatev,A.,Scheiffele,P.,Biederer,T.,Weiner,J.A.,Christopherson, K. S., and El-Husseini, A(2004), "Cell adhesionmolecules in synapse formation," The Journalofneuroscience,24,9244-9249.
  • Vessey,J.P.,Vaccani,A.,Xie,Y.,Dahm,R.,Karra,D.,Kiebler,M.A.,andMacchi,P(2006),"Dendritic localization ofthe translationalrepressorPumilio 2 and its contribution to dendritic stress granules," TheJournalofneuroscience,26,6496-6508.
  • Vessey,J.P.,Macchi,P.,Stein,J.M.,Mikl,M.,Hawker,K.N.,Vogelsang,P.,Wieczorek,K.,Vendra,G.,Riefler,J.,andTubing,F.,SamuelA.J. Aparicio,S A,J.,Abel,T.,and Kiebler,M,A(2008),"A loss offunction allele formurine Staufen1 leads to impairmentofdendriticStaufen1-RNP delivery and dendritic spine morphogenesis,"ProceedingsoftheNationalAcademyofSciences,105,16374-16379.
  • Van Leeuwen,F.N.,Kain,H.E.,Van Der Kammen,R.A.,Michiels,F.,Kranenburg,O.W.,and Collard,J.G(1997),"The guanine nucleotideexchangefactorTiam1affectsneuronalmorphology;opposingrolesforthe smallGTPases Rac and Rho,"The Journalofcellbiology,139,797-807.
  • Van Aelst,L.,and D’Souza-Schorey,C(1997),"Rho GTPases and signalingnetworks,"Genes& development,11,2295-2322.
  • Van Aelst,L.,and Cline,H.T(2004),"Rho GTPasesand activity-dependentdendritedevelopment,"Currentopinioninneurobiology,14,297-304.
  • Twiss, J. L., and Minnen, J. V(2006), "New insights into neuronalregeneration:the role ofaxonalprotein synthesis in pathfinding andaxonalextension,"Journalofneurotrauma,23,295-308.
  • Toni,N.,Buchs,P.A.,Nikonenko,I.,Bron,C.R.,andMuller,D(1999),"LTPpromotesformation ofmultiplespinesynapsesbetween asingleaxonterminalandadendrite,"Nature,402,421-425.
  • Tongiorgi,E.,Righi,M.,and Cattaneo,A(1997),"Activity-dependentdendritictargeting ofBDNF and TrkB mRNAs in hippocampalneurons,"TheJournalofneuroscience,17,9492-9505.
  • Tolias,K.F.,Bikoff,J.B.,Burette,A.,Paradis,S.,Harrar,D.,Tavazoie,S.,Weinberg,R,J.,and Greenberg,M.E(2005),"The Rac1-GEF Tiam1couplestheNMDA receptorto theactivity-dependentdevelopmentofdendriticarborsandspines,"Neuron,45,525-538.
  • Tolias, K. F., Duman, J. G., and Um, K(2011), "Control of synapsedevelopment and plasticity by Rho GTPase regulatory proteins,"Progressinneurobiology,94,133-148.
  • Threadgill,R.,Bobb,K.,andGhosh,A(1997),"Regulation ofdendriticgrowthandremodelingbyRho,Rac,andCdc42,"Neuron,19,625-634.
  • Teixeira, D., Sheth, U., Marco A., Valencia-sanchez, Brengues, M., andParker,R(2005),"Processing bodies require RNA for assembly andcontainnontranslatingmRNAs,"RNA,11,371-382.
  • Tashiro,A.,and Yuste,R(2004),"Regulation ofdendritic spine motility andstability by Rac1 and Rho kinase:evidence fortwo forms ofspinemotility,"MolecularandCellularNeuroscience,26,429-440.
  • Tang,S.J.,Meulemans,D.,Vazquez,L.,Colaco,N.,and Schuman,E(2001),"A role for a rathomolog ofstaufen in the transportofRNA toneuronaldendrites,"Neuron,32,463-475.
  • Takeuchi, T., Miyazaki, T., Watanabe,M., Mori,H.,Sakimura,K., andMishina, M(2005), "Control of synaptic connection by glutamatereceptorδ2in theadultcerebellum,"TheJournalofneuroscience,25,2146-2156.
  • Takai,Y.,Sasaki,T.,and Matozaki,T(2001),"SmallGTP-binding proteins,"Physiologicalreviews,81,153-208.
  • Swetloff,A.,Conne,B.,Huarte,J.,Pitetti,J.L.,Nef,S.,and Vassalli,J. D(2009),"Dcp1-bodies in mouse oocytes," Molecular biology ofthecell,20,4951-4961.
  • Sutton, M. A., and Schuman, E. M(2006), "Dendritic protein synthesis,synapticplasticity,andmemory,"Cell,127,49-58.
  • Steward,O.,andHalpain,S(1999),"Lamina-specificsynapticactivationcausesdomain-specificalterationsin dendriticimmunostaining forMAP2andCAM kinaseII,"TheJournalofneuroscience,19(18),7834-7845.
  • Stam,J.C.,andCollard,J.G(1999),“TheDH proteinfamily,exchangefactorsforRho-likeGTPases.In Cytoskeleton and SmallG Proteins” (pp. 51-83).SpringerBerlinHeidelberg,51-83.
  • Spires,T.L.,Grote,H.E.,Garry,S.,Cordery,P.M.,Van Dellen,A.,Blakemore,C.,andHannan,A.J(2004),"Dendriticspinepathology anddeficits in experience?dependent dendritic plasticity in R6/1Huntington's disease transgenic mice," European Journal ofNeuroscience,19,2799-2807.
  • Soderberg,O.,Gullberg,M.,Jarvius,M.,Ridderstrale,K.,Leuchowius,K.J.,Jarvius,J,and Landegren,U(2006),“Directobservation ofindividualendogenous protein complexes in situ by proximity ligation,” Naturemethods,3(12),995-1000.
  • Sin,W.C.,Haas,K.,Ruthazer,E.S.,andCline,H.T(2002),"Dendritegrowthincreased by visual activity requires NMDA receptor and RhoGTPases,"Nature,419,475-480.
  • Shin,E.Y.,Lee,C.S.,Cho,T.G.,Kim,Y.G.,Song,S.,Juhnn,Y.S.,ParkS,C.,Manser,E.,and Kim,E.G(2006),"βPak-interacting exchangefactor-mediated Rac1 activation requires smgGDS guanine nucleotideexchange factor in basic fibroblast growth factor-induced neuriteoutgrowth,"JournalofBiologicalChemistry,281,35954-35964.
  • Sheth,U.,andParker,R(2006),"Targeting ofaberrantmRNAstocytoplasmicprocessingbodies,"Cell,125,1095-1109.
  • Sheth,U.,and Parker,R(2003),"Decapping and decay ofmessenger RNAoccurincytoplasmicprocessingbodies,"Science,300,805-808.
  • Senda, T., Iino, S., Matsushita, K., Matsumine, A., Kobayashi, S., andAkiyama,T(1998),"Localization of the adenomatous polyposis colitumour suppressor protein in the mouse central nervous system,"Neuroscience,83,857-866.
  • Sen,G.L.,and Blau,H.M(2005),"Argonaute 2/RISC resides in sites ofmammalian mRNA decay known ascytoplasmic bodies,"Nature cellbiology,7,633-636.
  • Sekerkova,G.,Loomis,P.A.,Changyaleket,B.,Zheng,L.,Eytan,R.,Chen,B.,Mugnaini,E.,and Bartles,J.R(2003),"Novelespin actin-bundlingproteinsarelocalizedtoPurkinjecelldendriticspinesandbindtheSrchomology 3 adapter protein insulin receptor substrate p53," TheJournalofneuroscience,23,1310-1319.
  • Scott,E.K.,Reuter,J.E.,andLuo,L(2003),"SmallGTPaseCdc42isrequiredfor multiple aspects of dendritic morphogenesis," The Journal ofneuroscience,23,3118-3123.
  • Schuman,E.M.,Dynes,J.L.,and Steward,O(2006),"Synapticregulation oftranslation of dendritic mRNAs," The Journalofneuroscience,26,7143-7146.
  • Schratt,G.M.,Tuebing,F.,Nigh,E.A.,Kane,C.G.,Sabatini,M.E.,Kiebler,M.,andGreenberg,M.E(2006),"A brain-specificmicroRNA regulatesdendriticspinedevelopment,"Nature,439,283-289.
  • Schmidt,A.,andHall,A(2002),"GuaninenucleotideexchangefactorsforRhoGTPases: turning on the switch," Genes & development, 16,1587-1609.
  • Scheetz, A. J., Nairn, A. C., and Constantine-Paton, M(2000), "NMDAreceptor-mediatedcontrolofproteinsynthesisatdevelopingsynapses,"Natureneuroscience,3,211-216.
  • Sasaki,T.,and Takai,Y(1998),"The Rho smallG protein family-Rho GDIsystem asatemporalandspatialdeterminantforcytoskeletalcontrol,"Biochemicalandbiophysicalresearchcommunications,245,641-645.
  • Sasagawa,K.,Matsudo,Y.,Kang,M.,Fujimura,L.,Iitsuka,Y.,Okada,S.,Ochiai,T.,Tokuhisa,T.,and Hatano,M(2002),"Identification ofNd1,anovelmurinekelch family protein,involved in stabilization ofactinfilaments,"JournalofBiologicalChemistry,277,44140-44146.
  • Saneyoshi,T.,Wayman,G.,Fortin,D.,Davare,M.,Hoshi,N.,Nozaki,N.,Natsume, T., and Soderling, T. R(2008), “Activity-dependentsynaptogenesis:regulation by a CaM-kinase kinase/CaM-kinase I/βPIX signalingcomplex,”Neuron,57(1),94-107.
  • Rossman,K.L.,Der,C.J.,andSondek,J(2005),"GEF meansgo:turning onRHO GTPases with guanine nucleotide-exchange factors," NaturereviewsMolecularcellbiology,6,167-180.
  • Rook, M. S., Lu, M., and Kosik, K. S(2000), "CaMKIIα 3’-untranslatedregiondirected mRNA translocation in living neurons:visualization byGFP linkage,"TheJournalofNeuroscience,20,6385?6393.
  • Ridley,A.J.,Self,A.J.,Kasmi,F.,Paterson,H.F.,Hall,A.,Marshall,C.J.,and Ellis,C(1993),"rho family GTPase activating proteins p190,bcrand rhoGAP show distinct specificities in vitro and in vivo," TheEMBO Journal,12,5151.
  • Poulopoulos,A.,Aramuni,G.,Meyer,G.,Soykan,T.,Hoon,M.,Papadopoulos,T., Zhang, M., Paarmann, I., Fuchs, C., and Harvey, K(2009),"Neuroligin 2 drives postsynaptic assembly atperisomatic inhibitorysynapsesthroughgephyrinandcollybistin,"Neuron,63,628-642.
  • Pillai,R.S.,Bhattacharyya,S.N.,Artus,C.G.,Zoller,T.,Cougot,N.,Basyuk, E., and Filipowicz, W(2005), "Inhibition of translationalinitiation by Let-7 MicroRNA in human cells," Science, 309,1573-1576.
  • Pickett,J.,and London,E(2005),"The neuropathology ofautism:a review,"JournalofNeuropathology& ExperimentalNeurology,64,925-935.
  • Persico,A.M.,and Bourgeron,T(2006),"Searching for ways out of theautism maze:genetic,epigeneticand environmentalclues,"Trendsinneurosciences,29,349-358.
  • Penzes,P.,and Jones,K.A(2008),"Dendriticspinedynamics?akey roleforkalirin-7,"Trendsinneurosciences,31,419-427.
  • Penzes,P.,Johnson,R.C.,Sattler,R.,Zhang,X.,Huganir,R.L.,Kambampati,V.,Mains,R.E.,and Eipper,B.A(2001),"The NeuronalRho-GEFKalirin-7 Interacts with PDZ Domain-containing Proteins andRegulatesDendriticMorphogenesis,"Neuron,29,229-242.
  • Penzes,P.,Johnson,R.C.,Alam,M.R.,Kambampati,V.,Mains,R.E.,andEipper,B.A(2000),"An isoform ofkalirin,abrain-specificGDP/GTPexchange factor,is enriched in the postsynaptic density fraction,"JournalofBiologicalChemistry,275,6395-6403.
  • Penzes, P., Cahill, M. E., Jones, K. A., and Srivastava, D. P(2008),"Convergent CaMK and RacGEF signals controldendritic structureandfunction,"Trendsincellbiology,18,405-413.
  • Parnas,D.,Haghighi,A.P.,Fetter,R.D.,Kim,S.W.,and Goodman,C. S(2001)“Regulation ofpostsynaptic structure and protein localizationby the Rho-type guanine nucleotide exchange factordPix,” Neuron,32(3),415-424.
  • Parker, R., and Sheth, U(2007), "P bodies and the control of mRNAtranslationanddegradation,"Molecularcell,25,635-646.
  • Pak,D.T.,Yang,S.,Rudolph-Correia,S.,Kim,E.,and Sheng,M(2001),"Regulation of dendritic spine morphology by SPAR, aPSD-95-associatedRapGAP,"Neuron,31,289-303.
  • Olofsson,B(1999),“Rho guanine dissociation inhibitors:pivotalmolecules incellularsignaling,”Cellularsignalling,11(8),545-554.
  • Okamoto,K.,Bosch,M.,and Hayashi,Y(2009),"The roles ofCaMKIIandF-actin in the structuralplasticity of dendritic spines:a potentialmolecularidentityofasynaptictag?,"Physiology,24,357-366.
  • Oh,J.Y.,Nam,Y.J.,Jo,A.,Cheon,H.S.,Rhee,S.M.,Park,J.K.,Lee,J. A.,and Kim,H.K(2010b),"Apolipoprotein E mRNA istransported todendrites and may have a role in synaptic structural plasticity,"Journalofneurochemistry,114,685-696.
  • Oh,D.,Han,S.,Seo,J.,Lee,J.R.,Choi,J.,Groffen,J.,...andKim,E(2010a),"Regulation of synaptic Rac1 activity, long-term potentiationmaintenance, and learning and memory by BCR and ABR RacGTPase-activating proteins," The Journal of Neuroscience, 30,14134-14144.
  • Ng,J.,Nardine,T.,Harms,M.,Tzu,J.,Goldstein,A.,Sun,Y.,Dietzl,G.,Dickson,B,J.,and Luo,L(2002),“RacGTPasescontrolaxon growth,guidanceandbranching,” Nature,416(6879),442-447.
  • Newey,S.E.,Velamoor,V.,Govek,E.E.,and Van Aelst,L(2005),"RhoGTPases, dendritic structure, and mental retardation," Journal ofneurobiology,64,58-74.
  • Negishi, M., and Katoh, H(2005), "Rho family GTPases and dendriteplasticity,"TheNeuroscientist,11,187-191.
  • Nam,Y.J.,Cheon,H.S.,Choi,Y.K.,Kim,S.Y.,Shin,E.Y.,Kim,E.G.,and Kim, H. K(2008), "Role of mitogen-activated protein kinase(MAPK) docking sites on Staufen2 protein in dendritic mRNAtransport,"Biochemicaland biophysicalresearchcommunications,372,525-529.
  • Nakayama,A.Y.,Harms,M.B.,andLuo,L(2000),"SmallGTPasesRacandRho in the maintenance of dendritic spines and branches inhippocampalpyramidalneurons," The Journal ofNeuroscience,20,5329-5338.
  • Murakoshi,H.,Wang,H.,andYasuda,R(2011),"Local,persistentactivationofRhoGTPasesduringplasticityofsingledendriticspines,"Nature,472,100-104.
  • Mori,Y.,Imaizumi,K.,Katayama,T.,Yoneda,T.,and Tohyama,M(2000),"Two cis-acting elements in the 3’-UTR of CaMKIIα regulate itsdendritictargeting,"NatureNeuroscience,3,1079?1084.
  • Moon,S.Y.,and Zheng,Y(2003),"Rho GTPase-activating proteins in cellregulation,"Trendsincellbiology,13,13-22.
  • Miller,S.,Yasuda,M.,Coats,J.K.,Jones,Y.,Martone,M.E.,andMayford,M(2002), “Disruption of dendritic translation of CaMKIIα impairsstabilization ofsynapticplasticity and memory consolidation,”Neuron,36(3),507-19.
  • Miki,T.,Takano,K.,and Yoneda,Y(2005),"Theroleofmammalian Staufenon mRNA traffic: a view from its nucleocytoplasmic shuttlingfunction,"Cellstructureandfunction,30,51-56.
  • Meister,G.,Landthaler,M.,Peters,L.,Chen,P.Y.,Urlaub,H.,Luhrmann,R.,and Tuschl, T(2005), "Identification of novel argonaute-associatedproteins,"Currentbiology,15,2149-2155.
  • Matus,A(2005),"Growth ofdendritic spines:a continuing story," Currentopinioninneurobiology,15,67-72.
  • Matus,A(2000),"Actin-based plasticity in dendritic spines," Science,290,754-758.
  • Matsuzaki, M., Honkura, N., Ellis-Davies, G. C., and Kasai, H(2004),"Structuralbasisoflong-term potentiation in singledendriticspines,"Nature,429,761-766.
  • Martel,C.,Macchi,P.,Furic,L.,Kiebler,M.,and Desgroseillers,L(2006),"Staufen1 is imported into the nucleolus via a bipartite nuclearlocalization signaland severalmodulatory determinants,"BiochemicalJournal,393,245-254.
  • Marrs,G.S.,Green,S.H.,and Dailey,M.E(2001),"Rapid formation andremodeling ofpostsynaptic densities in developing dendrites,"Natureneuroscience,4,1006-1013.
  • Marion,R.M.,Fortes,P.,Beloso,A.,Dotti,C.,andOrtin,J(1999),"A humansequence homologue ofStaufen is an RNA-binding protein thatisassociated with polysomes and localizes to the rough endoplasmicreticulum,"Molecularandcellularbiology,19,2212-2219.
  • Manser,E.,Leung,T.,Salihuddin,H.,Zhao,Z.S.,andLim,L(1994),"A brainserine/threonineprotein kinaseactivated by Cdc42and Rac1,"Nature,367,40-46
  • Ma,X.M.,Kiraly,D.D.,Gaier,E.D.,Wang,Y.,Kim,E.J.,Levine,E.S.,Eipper, B. A.,and Mains,R. E(2008), "Kalirin-7 is required forsynaptic structure and function," The JournalofNeuroscience,28,12368-12382.
  • Ma,X.M.,Huang,J.,Wang,Y.,Eipper,B.A.,and Mains,R.E(2003),"Kalirin,a multifunctionalRho guaninenucleotideexchangefactor,isnecessary formaintenanceofhippocampalpyramidalneuron dendritesanddendriticspines,"TheJournalofneuroscience,23,10593-10603.
  • Lynch, G. S., Dunwiddie, T., and Gribkoff, V(1977), "Heterosynapticdepression:apostsynapticcorrelateoflong-term potentiation,"Nature,266,737-739Lynch, M. A(2004), "Long-term potentiation and memory," Physiologicalreviews,84,87-136.
  • Luo,L.,Hensch,T.K.,Ackerman,L.,Barbel,S.,Jan,L.Y.,and Jan,Y. N(1996),"Differential effects of the Rac GTPase on Purkinje cellaxonsanddendritictrunksandspines,"Nature,379,837-840.
  • Liu,J.,Rivas,F.V.,Wohlschlegel,J.,Yates,J.R.,Parker,R.,andHannon,G. J(2005),"A role for the P-body component GW182 in microRNAfunction,"Naturecellbiology,7,1261-1266.
  • LiC.H.,Irmer H,Gudjonsdottir-Planck D,Freese S,Salm H,Haile S,EstevezAM,andClaytonC(2006),“RolesofaTrypanosomabrucei5'→3' exoribonuclease homolog in mRNA degradation,” RNA,12(12),2171-86.
  • Li,Z.,Aizenman,C.D.,andCline,H.T.(2002),"Regulation ofrhoGTPasesbycrosstalkandneuronalactivityinvivo,"Neuron,33,741-750.
  • Lewis,D.A.,Glantz,L.A.,Pierri,J.N.,and Sweet,R.A(2003),"Alteredcorticalglutamate neurotransmission in schizophrenia,"Annals oftheNew YorkAcademyofSciences,1003,102-112.
  • Lendvai, B., Stern, E. A., Chen, B., and Svoboda, K(2000),"Experience-dependentplasticity ofdendriticspines in the developingratbarrelcortexinvivo,"Nature,404,876-881.
  • Lee,T.,Winter,C.,Marticke,S.S.,Lee,A.,and Luo,L(2000),"EssentialrolesofDrosophila RhoA in theregulation ofneuroblastproliferationanddendriticbutnotaxonalmorphogenesis,"Neuron,25,307-316.
  • Lee,J.H.,Oh,J.Y.,Pascua,P.N.Q.,Kim,E.G.,Choi,Y.K.,andKim,H. K(2011), "Impairment of the Staufen1-NS1 interaction reducesinfluenza viral replication," Biochemical and biophysical researchcommunications,414,153-158.
  • Lee,H.K.,Kameyama,K.,Huganir,R.L.,and Bear,M.F(1998),"NMDAinduces long-term synaptic depression and dephosphorylation oftheGluR1 subunit of AMPA receptors in hippocampus," Neuron, 21,1151-1162.
  • Lamprecht, R.,and LeDoux,J.(2004),"Structural plasticity and memory,"NatureReviewsNeuroscience,5,45-54.
  • Kunda,P.,Paglini,G.,Quiroga,S.,Kosik,K.,andCaceres,A(2001),"Evidencefor the involvement of Tiam1 in axon formation," The JournalofNeuroscience,21,2361-2372.
  • Krichevsky,A.M.,and Kosik,K.S(2001),"NeuronalRNA granules:a linkbetween RNA localization and stimulation-dependent translation,"Neuron,32,683-696.
  • Kramer,S.,Queiroz,R.,Ellis,L.,Webb,H.,Hoheisel,J.D.,Clayton,C.,andCarrington,M(2008),"Heatshockcausesadecreasein polysomesandthe appearance ofstress granules in trypanosomes independently ofeIF2α phosphorylation at Thr169," Journal of cell science, 121,3002-3014.
  • Korobova,F.,andSvitkina,T(2010),"Moleculararchitectureofsynapticactincytoskeleton in hippocampalneuronsrevealsamechanism ofdendriticspinemorphogenesis,"Molecularbiologyofthecell,21,165-176.
  • Kohrmann,M.,Luo,M.,Kaether,C.,DesGroseillers,L.,Dotti,C.G.,andKiebler, M. A(1999), "Microtubule-dependent recruitment ofStaufen-green fluorescentprotein into largeRNA-containing granulesand subsequent dendritic transport in living hippocampalneurons,"Molecularbiologyofthecell,10,2945-2953.
  • Knobloch,M.,and Mansuy,I.M(2008),"Dendritic spine loss and synapticalterationsinAlzheimer'sdisease,"Molecularneurobiology,37,73-82.
  • Klann,E.,Antion,M.D.,Banko,J.L.,andHou,L(2004),"Synapticplasticityandtranslationinitiation,"Learning & Memory,11,365-372.
  • Kiraly,D.D.,Eipper-Mains,J.E.,Mains,R.E.,and Eipper,B.A(2010),"Synapticplasticity,asymphonyinGEF,"ACS chemicalneuroscience,1,348-365.
  • Kins, S., Betz, H., and Kirsch, J(2000), "Collybistin, a newly identifiedbrain-specific GEF, induces submembrane clustering of gephyrin,"Natureneuroscience,3,22-29.
  • Kiebler,M.A.,andBassell,G.J(2006),"NeuronalRNA granules:moversandmakers,"Neuron,51,685-690.
  • Kedersha,N.,Stoecklin,G.,Ayodele,M.,Yacono,P.,Lykke-Andersen,J.,Fritzler,M.J., Scheuner,D.,Kaufman,R. J.,Golan,D.E.,andAnderson, P(2005), "Stress granules and processing bodies aredynamically linked sites ofmRNP remodeling," The Journalofcellbiology,169,871-884.
  • Kawauchi,T.,Chihama,K.,Nabeshima,Y.I.,andHoshino,M(2003),"Theinvivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronalmigration,"TheEMBO journal,22,4190-4201.
  • Kawasaki,Y.,Senda,T.,Ishidate,T.,Koyama,R.,Morishita,T.,Iwayama,Y.,and Akiyama,T(2000),“Asef,a link between the tumor suppressorAPC andG-proteinsignaling,”Science,289(5482),1194-1197.
  • Kawasaki,Y.,Sato,R.,and Akiyama,T(2003),"Mutated APC and Asefareinvolved in the migration of colorectaltumour cells," Nature cellbiology,5,211-215.
  • Kasri,N.N.,and Van Aelst,L(2008),"Rho-linked genes and neurologicaldisorders," Pflugers Archiv-European Journal of Physiology, 455,787-797.
  • Kasri,N.N.,Nakano-Kobayashi,A.,andVanAelst,L(2011),"Rapidsynthesisof the X-linked mental retardation protein OPHN1 mediatesmGluR-dependent LTD through interaction with the endocyticmachinery,"Neuron,72,300-315.
  • Kandel,E.R(2001),"The molecularbiology ofmemory storage:a dialoguebetweengenesandsynapses,"Science,294,1030-1038.
  • Kalkman,H.O(2012),"A review of the evidence for the canonicalWntpathwayinautism spectrum disorders,"MolecularAutism,3,10-Kanai,Y.,Dohmae,N.,and Hirokawa,N(2004),"Kinesin transports RNA:isolation and characterization of an RNA-transporting granule,"Neuron,43,513-525.
  • Ju,W.,Morishita,W.,Tsui,J.,Gaietta,G.,Deerinck,T.J.,Adams,S.R.,Garner,C.C.,Tsien,R.Y.,Ellisman,M.H.,andMalenka,R.C(2004),"Activity-dependentregulationofdendriticsynthesisandtrafficking ofAMPA receptors,"Natureneuroscience,7,244-253.
  • Johnson,R.C.,Penzes,P.,Eipper,B.A.,andMains,R.E(2000),"Isoformsofkalirin,a neuronal dbl family member,generated through use ofdifferent5’- and3’-endsalong with an internaltranslationalinitiationsite,"JournalofBiologicalChemistry,275,19324?19333.
  • Jiang,C.,andSchuman,E.M(2002),"Regulation andfunctionoflocalproteinsynthesis in neuronaldendrites,"Trends in biochemicalsciences,27,506-513.
  • Jeong,J.H.,Nam,Y.J.,Kim,S.Y.,Kim,E.G.,Jeong,J.,and Kim,H. K(2007), "The transport of Staufen2-containing ribonucleoproteincomplexes involves kinesin motor protein and is modulated bymitogen-activated protein kinasepathway,"Journalofneurochemistry,102,2073-2084.
  • Jakymiw,A.,Lian,S.,Eystathioy,T.,Li,S.,Satoh,M.,Hamel,J.C.,FritzlerM. J.,and Chan,E.K(2005),"Disruption of GW bodies impairsmammalianRNA interference."Naturecellbiology,7(12),1267-1274.
  • Ishikawa,R.,Katoh,K.,Takahashi,A.,Xie,C.,Oseki,K.,Watanabe,M.,Igarashi,M.,Nakamura,A.,andKohama,K(2007),"Drebrinattenuatesthe interaction between actin and myosin-V," Biochemical andbiophysicalresearchcommunications,359,398-401.
  • Huttelmaier,S.,Zenklusen,D.,Lederer,M.,Dictenberg,J.,Lorenz,M.,Meng,X.,Bassell,G.J.,Condeelis,J.,and Singer,R.H(2005),"Spatialregulation ofβ-actin translation by Src-dependentphosphorylation ofZBP1,"Nature,438(7067),512-515.
  • Hoyle,N.P.,Castelli,L.M.,Campbell,S.G.,Holmes,L.E.,and Ashe,M. P(2007), "Stress-dependent relocalization of translationally primedmRNPs to cytoplasmic granules that are kinetically and spatiallydistinctfrom P-bodies."TheJournalofcellbiology,179(1),65-74.
  • Hotulainen, P., and Hoogenraad, C. C(2010), “Actin in dendritic spines:connecting dynamicstofunction,”TheJournalofcellbiology,189(4),619-629.
  • Honkura,N.,Matsuzaki,M.,Noguchi,J.,Ellis-Davies,G.C.,and Kasai,H(2008), “The subspine organization of actin fibers regulates thestructureandplasticityofdendriticspines,”Neuron,57(5),719-729.
  • Holetz,F.B.,Correa,A.,Avila,A.R.,Nakamura,C.V.,Krieger,M.A.,andGoldenberg, S(2007), "Evidence of P-body-like structures inTrypanosoma cruzi," Biochemical and biophysical researchcommunications,356,1062-1067.
  • Hirokawa,N.,and Takemura,R(2005),"Molecularmotorsand mechanismsofdirectionaltransport in neurons," Nature Reviews Neuroscience,6,201-214.
  • Hirokawa,N(2006),"mRNA transportindendrites:RNA granules,motors,andtracks,"TheJournalofneuroscience,26,7139-7142.
  • Hering, H., and Sheng, M(2003), "Activity-dependent redistribution andessential role of cortactin in dendritic spine morphogenesis," TheJournalofneuroscience,23,11759-11769.
  • Harvey,K.,Duguid,I.C.,Alldred,M.J.,Beatty,S.E.,Ward,H.,Keep,N.H.,.,Lingenfelter,S.E.,Pearce,B.R.,Lundgren,J.,and Owen,M.J.,Smart,T.J.,Luscher,B.,Rees,M.I.,and Harvey,R.J(2004),"TheGDP-GTP exchange factor collybistin:an essential determinant ofneuronal gephyrin clustering," The Journal of neuroscience, 24,5816-5826.
  • Harris,K.M(1994),"Dendriticspines,"eLS,Harris, K. M(1999), "Structure, development, and plasticity of dendriticspines,"Currentopinioninneurobiology,9,343-348.
  • Hamann,M.J.,Lubking,C.M.,Luchini,D.N.,and Billadeau,D.D(2007),"Asef2functionsasaCdc42exchangefactorandisstimulatedbytherelease of an autoinhibitory module from a concealed C-terminalactivationelement,"Molecularandcellularbiology,27,1380-1393.
  • Grooms,S.Y.,Noh,K.M.,Regis,R.,Bassell,G.J.,Bryan,M.K.,Carroll,R. C.,and Zukin,R.S(2006),"Activity bidirectionally regulates AMPAreceptormRNA abundancein dendritesofhippocampalneurons,"TheJournalofneuroscience,26,8339-8351.
  • Govek,E.E.,Newey,S.E.,and Van Aelst,L(2005),"The role ofthe RhoGTPasesinneuronaldevelopment,"Genes& development,19,1-49.
  • Gotthardt,K.,and Ahmadian,M.R(2007),"Asefisa Cdc42-specificguaninenucleotideexchangefactor,"Biologicalchemistry,388,67-71.
  • Goetze,B.,Tuebing,F.,Xie,Y.,Dorostkar,M.M.,Thomas,S.,Pehl,U.,Boehm,S.,Macchi,P.,and Kiebler,M.A(2006),"The brain-specificdouble-stranded RNA-binding protein Staufen2 is required fordendritic spine morphogenesis," The Journal of cell biology, 172,221-231.
  • Fujii,R.,andTakumi,T(2005),“TLS facilitatestransportofmRNA encodinganactin-stabilizingproteintodendriticspines,”Journalofcellscience,118(24),5755-5765.
  • Franks, T. M., and Lykke-Andersen, J(2008), "The control of mRNAdecappingandP-bodyformation,"Molecularcell,32,605-615.
  • Fodde,R.,Kuipers,J.,Rosenberg,C.,Smits,R.,Kielman,M.,Gaspar,C.,vanEs,J.H.,Breukel,C.,Wiegant,J.,Giles,R.H.,andClevers,H(2001),"Mutations in the APC tumoursuppressorgene cause chromosomalinstability,"Naturecellbiology,3,433-438.
  • Finch,R.,Moore,H.G.,Lindor,N.,Jalal,S.M.,Markowitz,A.,Jhanwar,S.,Offit,K.,andGuillem,J.G(2005),"Familialadenomatouspolyposisandmental retardation caused by a de novo chromosomaldeletion at5q15-q22:report ofa case," Diseases ofthe colon & rectum,48,2148-2152.
  • Eulalio, A., Behm-Ansmant, I., Schweizer, D., and Izaurralde, E(2007),"P-body formation isaconsequence,notthecause,ofRNA-mediatedgenesilencing,"Molecularandcellularbiology,27,3970-3981.
  • Ethell,I.M.,and Pasquale,E.B(2005),"Molecularmechanisms ofdendriticspine development and remodeling," Progress in neurobiology,75,161-205.
  • Engert,F.,and Bonhoeffer,T(1999),"Dendriticspinechangesassociated withhippocampallong-term synapticplasticity,"Nature,399,66-70.
  • Dugre-Brisson,S.,Elvira,G.,Boulay,K.,Chatel-Chaix,L.,Mouland,A.J.,and DesGroseillers,L(2005),"InteractionofStaufen1withthe5endofmRNA facilitatestranslationoftheseRNAs,"NucleicAcidsResearch,33,4797-4812.
  • Duchaine,T.F.,Hemraj,I.,Furic,L.,Deitinghoff,A.,Kiebler,M.A.,andDesGroseillers, L(2002), "Staufen2 isoforms localize to thesomatodendritic domain of neurons and interact with differentorganelles,"Journalofcellscience,115,3285-3295
  • DerMardirossian,C.,Schnelzer,A.,and Bokoch,G.M(2004),"PhosphorylationofRhoGDIby Pak1mediatesdissociation ofRacGTPase,"Molecularcell,15,117-127.
  • DerMardirossian, C., and Bokoch, G. M(2005), "GDIs: central regulatorymolecules in Rho GTPase activation," Trends in cell biology,15,356-363.
  • Debant,A.,Serra-Pages,C.,Seipel,K.,O'Brien,S.T.E.P.H.E.N.,Tang,M.,Park,S.H.,and Streuli,M(1996),"Themultidomain protein Triobinds the LAR transmembrane tyrosine phosphatase, contains aprotein kinasedomain,and hasseparaterac-specificand rho-specificguanine nucleotide exchange factor domains," Proceedings of theNationalAcademyofSciences,93,5466-5471.
  • DeGeer,J.,andLamarche-Vane,N(2013),"RhoGTPasesinneurodegenerationdiseases,"Experimentalcellresearch,319,2384-2394.
  • De Roo, M., Klauser, P., Mendez, P., Poglia, L., and Muller, D(2008),"Activity-dependentPSD formation and stabilization ofnewly formedspinesinhippocampalslicecultures,"Cerebralcortex,18,151-161.
  • Day,M.,Wang,Z.,Ding,J.,An,X.,Ingham,C.A.,Shering,A.F.,Wokosin,D.,Ilijic,E.,Sun,Z.,Sampson,A.R.,Mugnaini,E.,Deutch,A.Y.,Sesack,S.R.,Arbuthnott,G.W.,and Surmeie,D.J(2006),"Selectiveelimination of glutamatergic synapses on striatopallidal neurons inParkinsondiseasemodels,"Natureneuroscience,9,251-259.
  • Dailey,M.E.,andSmith,S.J(1996),"Thedynamicsofdendriticstructureindeveloping hippocampal slices," The Journal of neuroscience, 16,2983-2994.
  • Cui,D.H.,Jiang,K.D.,Jiang,S.D.,Xu,Y.F.,and Yao,H(2005),"Thetumorsuppressoradenomatouspolyposiscoligeneisassociated withsusceptibilitytoschizophrenia,"Molecularpsychiatry,10,669-677.
  • Cougot,N.,Babajko,S.,andSeraphin,B(2004),"CytoplasmicfociaresitesofmRNA decayinhumancells,"TheJournalofcellbiology,165,31-40.
  • Cougot, N., Bhattacharyya, S. N., Tapia-Arancibia, L., Bordonne, R.,Filipowicz, W., Bertrand, E., and Rage, F(2008), "Dendrites ofmammalian neurons contain specialized P-body-like structures thatrespond to neuronalactivation," The Journal ofNeuroscience,28,13793-13804.
  • Coller,J.,and Parker,R(2005),"Generaltranslationalrepression by activatorsofmRNA decapping,"Cell, 122(6),875-886.
  • Clevers,H.,and Nusse,R(2012),"Wnt/β-catenin signaling and disease,"Cell,149,1192-1205.
  • Cingolani,L.A.,and Goda,Y(2008),"Actin in action:the interplay betweenthe actin cytoskeleton and synaptic efficacy," Nature ReviewsNeuroscience,9,344-356.
  • Caloca, M., Wang, H., and Kazanietz, M(2003), "Characterization of theRac-GAP (Rac-GTPase-activating protein)activity ofβ2-chimaerin,a‘non-proteinkinaseC’phorbolesterreceptor,"BiochemicalJournal,375,313-321.
  • Burgess,A.W.,Faux,M.C.,Layton,M.J.,and Ramsay,R.G(2011),"Wntsignaling and colon tumorigenesis - A view from the periphery,"Experimentalcellresearch,317,2748-2758.
  • Buchan,J.R.,and Parker,R(2009),"Eukaryoticstressgranules:theinsandoutsoftranslation,"Molecularcell,36,932-941.
  • Brengues,M.,Teixeira,D.,and Parker,R(2005),"Movement of eukaryoticmRNAs between polysomes and cytoplasmic processing bodies,"Science,310,486-489.
  • Bramham, C. R., and Wells, D. G(2007), "Dendritic mRNA: transport,translationandfunction,"NatureReviewsNeuroscience,8,776-789.
  • Brakeman,J.S.F.,Gu,S.H.,Wang,X.B.,Dolin,G.,and Baraban,J. M(1999),"Neuronal localization of the Adenomatous polyposis colitumorsuppressorprotein,"Neuroscience,91,661-672.
  • Bourne,J.N.,and Harris,K.M(2008),"Balancing structure and function athippocampaldendriticspines,"Annualreview ofneuroscience,31,47.
  • Boda,B.,Dubos,A.,and Muller,D(2010),"Signaling mechanisms regulatingsynapseformationandfunctioninmentalretardation,"Currentopinioninneurobiology,20,519-527.
  • Blumenthal,J.,and Ginzburg,I(2008),"Zinc as a translation regulator inneurons:implicationsforP-body aggregation,"Journalofcellscience,121,3253-3260.
  • Bishop,A.L.H.A.,and Alan Hall(2000),"Rho GTPases and theireffectorproteins,"BiochemicalJournal,348,241-255.
  • Bienz, M(2002), "The subcellular destinations of APC proteins," NatureReviewsMolecularCellBiology,3,328-338.
  • Bhattacharyya, S. N., Habermacher, R., Martine, U., Closs, E. I., andFilipowicz,W(2006),"Stress-induced reversalofmicroRNA repressionand mRNA P-body localization in human cells,"Cold Spring Harborsymposiaonquantitativebiology,71,513-521.
  • Bhatt,D.H.,Zhang,S.,and Gan,W.B(2009),"Dendritic spine dynamics,"Annualreview ofphysiology,71,261-282.
  • Bernards,A.,and Settleman,J(2004),"GAP control:regulating theregulatorsofsmallGTPases,"Trendsincellbiology,14,377-385.
  • Benard,V.,Bohl,B.P.,andBokoch,G.M(1999),"Characterizationofracandcdc42 activation in chemoattractant-stimulated human neutrophilsusing a novel assay for active GTPases," Journal of BiologicalChemistry,274,13198-13204.
  • Behm-Ansmant, I., Rehwinkel, J., Doerks, T., Stark, A., Bork, P., andIzaurralde, E(2006), "mRNA degradation by miRNAs and GW182requires both CCR4:NOT deadenylase and DCP1:DCP2 decappingcomplexes,"Genes& development,20,1885-1898.
  • Barth,AngelaI.,HectorY.Caro-Gonzalez.,and W.J.Nelson(2008),"Roleofadenomatouspolyposiscoli(APC)and microtubulesin directionalcellmigration and neuronal polarization," Seminars in cell &developmentalbiology,19,245-251.
  • Barbee,S.A.,Estes,P.S.,Cziko,A.M.,Hillebrand,J.,Luedeman,R.A.,Coller,J.M.,Johnson,N.,Howlett,I.C.,Geng,C.,and Ueda,R.,Brand, A. H., Newbury, S, F., Wilhelm, J. E., Levine, R. B.,Nakamura,A.,and Parker,R(2006),"Staufen-and FMRP-containingneuronalRNPs are structurally and functionally related to somatic Pbodies,"Neuron,52,997-1009.
  • Bagni,C.,and Greenough,W.T(2005),"From mRNP trafficking to spinedysmorphogenesis:therootsoffragileX syndrome,"Nature ReviewsNeuroscience,6,376-387.
  • Aoki,K.,and Taketo,M.M(2007),"Adenomatous polyposis coli(APC):amulti-functionaltumorsuppressorgene,"Journalofcellscience,120,3327-3335.
  • Andrei MA., Ingelfinger D, Heintzmann R, Achsel T, Rivera-Pomar R,Luhrmann R(2005), "A role for eIF4E and eIF4E-transporter intargetingmRNPstomammalianprocessingbodies,"RNA,11,717-727.
  • Anderson,P.,and Kedersha,N(2006),"RNA granules,"The Journalofcellbiology,172,803-808.
  • Andersen,P.,S.H.Sundberg,O.Sveen,and H.Wigstrom(1977),"Specificlong-lasting potentiation of synaptic transmission in hippocampalslices,"Nature, 266,736? 737.
  • Alam,M.R.,Richard C.Johnson,DanielN.Darlington,Tracey A.Hand,Richard E.Mains,and Betty A.Eipper(1997),"Kalirin,a cytosolicproteinwith spectrin-likeandGDP/GTP exchangefactor-likedomainsthat interacts with peptidylglycine α-amidating monooxygenase,anintegralmembrane peptide-processing enzyme,"JournalofBiologicalChemistry,272,12667-12675.
  • Ahmed,S.,J.Lee,R.Kozma,A.Best,C.Monfries,and L.Lim(1993),"Anovel functional target for tumor-promoting phorbol esters andlysophosphatidic acid. The p21rac-GTPase activating proteinn-chimaerin,"JournalofBiologicalChemistry,268,10709-10712.
  • Ackermann,M.,and Matus,A(2003),“Activity-induced targeting ofprofilinand stabilization ofdendriticspinemorphology,”Nature neuroscience,6(11),1194-1200.