연구동향 분석
박사

Development of therapeutical materials for inflammatory diseases: Rheumatoid arthritis, Atopic dermatitis, Allergic contact dermatitis : 염증성질환의 치료물질 개발 및 작용기전의 이해: 류마티스 관절염, 아토피피부염, 알레르기접촉 피부염

최진경 2015년

논문상세정보
인용/피인용
' Development of therapeutical materials for inflammatory diseases: Rheumatoid arthritis, Atopic dermatitis, Allergic contact dermatitis : 염증성질환의 치료물질 개발 및 작용기전의 이해: 류마티스 관절염, 아토피피부염, 알레르기접촉 피부염' 의 주제별 논문영향력
논문영향력 선정 방법
논문영향력 요약
주제
  • allergic contact dermatitis
  • atopic dermatitis
  • rheumatoid arthritis
동일주제 총논문수 논문피인용 총횟수 주제별 논문영향력의 평균
500 0

0.0%

' Development of therapeutical materials for inflammatory diseases: Rheumatoid arthritis, Atopic dermatitis, Allergic contact dermatitis : 염증성질환의 치료물질 개발 및 작용기전의 이해: 류마티스 관절염, 아토피피부염, 알레르기접촉 피부염' 의 참고문헌

  • van den Berg, W.B., Miossec, P., 2009. IL-17 as a future therapeutic target for rheumatoid arthritis. Nature Reviews Rheumatology 5, 549-553.
  • van den Berg, W.B., Miossec, P., 2009. IL-17 as a future therapeutic target for rheumatoid arthritis. Nat. Rev. Rheumatol. 5, 549-553.
  • van Roon, J.A., Glaudemans, C.A., Bijlsma, J.W., Lafeber, F.P., 2003. Differentiation of naive CD4+ T cells towards T helper 2 cells is not impaired in rheumatoid arthritis patients. Arthritis. Res. Ther. 5, R269-276.
  • Zutshi, D., Mason, M., 1976. Ketoprofen in rheumatoid arthritis: its tolerance and therapeutic effect. Scand J Rheumatol Suppl 1976, 77-84.
  • Ziegler, S.F., Artis, D., 2010. Sensing the outside world: TSLP regulates barrier immunity. Nat Immunol 11, 289-293.
  • Youn, J., Lee, K.H., Won, J., Huh, S.J., Yun, H.S., Cho, W.G., Paik, D.J., 2003. Beneficial effects of rosmarinic acid on suppression of collagen induced arthritis. J Rheumatol 30, 1203-1207.
  • Yoshioka, Y., Kozawa, E., Urakawa, H., Arai, E., Futamura, N., Zhuo, L., Kimata, K., Ishiguro, N., Nishida, Y., 2013. Suppression of hyaluronan synthesis alleviates inflammatory responses in murine arthritis and in human rheumatoid synovial fibroblasts. Arthritis Rheum 65, 1160-1170.
  • Xuzhu, G., Komai-Koma, M., Leung, B.P., Howe, H.S., McSharry, C., McInnes, I.B., Xu, D., 2012. Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function. Ann Rheum Dis 71, 129-135.
  • Xu, H., He, Y., Yang, X., Liang, L., Zhan, Z., Ye, Y., Lian, F., Sun, L., 2007. Antimalarial agent artesunate inhibits TNF-alpha-induced production of proinflammatory cytokines via inhibition of NF-kappaB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes. Rheumatology. (Oxford). 46, 920-926.
  • Xu, D., Jiang, H.R., Kewin, P., Li, Y., Mu, R., Fraser, A.R., Pitman, N., Kurowska-Stolarska, M., McKenzie, A.N., McInnes, I.B., Liew, F.Y., 2008. IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proc Natl Acad Sci U S A 105, 10913-10918.
  • Xiao, T., Kagami, S., Saeki, H., Sugaya, M., Kakinuma, T., Fujita, H., Yano, S., Mitsui, H., Torii, H., Komine, M., Asahina, A., Nakamura, K., Tamaki, K., 2003. Both IL-4 and IL-13 inhibit the TNF-alpha and IFN-gamma enhanced MDC production in a human keratinocyte cell line, HaCaT cells. J Dermatol Sci 31, 111- 117.
  • Wisler, B.A., Dennis, J.E., Malemud, C.J., 2011. New Organ-Specific Pharmacological Strategies Interfering With Signaling Pathways In Inflammatory Disorders/Autoimmune Disorders. Current Signal Transduction Therapy 6, 279-291.
  • Wisler, B.A., Dennis, J.E., Malemud, C.J., 2011. New Organ-Specific Pharmacological Strategies Interfering With Signaling Pathways In Inflammatory Disorders/Autoimmune Disorders. Curr. Signal. Transduct. Ther. 6, 279-291.
  • Vocanson, M., Hennino, A., Chavagnac, C., Saint-Mezard, P., Dubois, B., Kaiserlian, D., Nicolas, J.F., 2005. Contribution of CD4(+ )and CD8(+) Tcells in contact hypersensitivity and allergic contact dermatitis. Expert Rev Clin Immunol 1, 75-86.
  • Vestergaard, C., Bang, K., Gesser, B., Yoneyama, H., Matsushima, K., Larsen, C.G., 2000. A Th2 chemokine, TARC, produced by keratinocytes may recruit CLA+CCR4+ lymphocytes into lesional atopic dermatitis skin. J Invest Dermatol 115, 640-646.
  • Verhoef, C.M., van Roon, J.A., Vianen, M.E., Lafeber, F.P., Bijlsma, J.W., 1999. The immune suppressive effect of dexamethasone in rheumatoid arthritis is accompanied by upregulation of interleukin 10 and by differential changes in interferon gamma and interleukin 4 production. Ann Rheum Dis 58, 49-54.
  • Trifari, S., Kaplan, C.D., Tran, E.H., Crellin, N.K., Spits, H., 2009. Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells. Nat Immunol 10, 864-871.
  • Trautmann, A., Akdis, M., Schmid-Grendelmeier, P., Disch, R., Brocker, E.B., Blaser, K., Akdis, C.A., 2001. Targeting keratinocyte apoptosis in the treatment of atopic dermatitis and allergic contact dermatitis. J Allergy Clin Immunol 108, 839-846.
  • Toda, M., Leung, D.Y.M., Molet, S., Boguniewicz, M., Taha, R., Christodoulopoulos, P., Fukuda, T., Elias, J.A., Hamid, Q.A., 2003. Polarized in vivo expression of IL-11 and IL-17 between acute and chronic skin lesions. J Allergy Clin Immun 111, 875-881.
  • Tian, J., Chen, J.W., Gao, J.S., Li, L., Xie, X., 2013. Resveratrol inhibits TNFalpha- induced IL-1beta, MMP-3 production in human rheumatoid arthritis fibroblast-like synoviocytes via modulation of PI3kinase/Akt pathway. Rheumatol Int 33, 1829-1835.
  • Takeuchi, O., Akira, S., 2010. Pattern recognition receptors and inflammation. Cell 140, 805-820.
  • Takayanagi, H., Ogasawara, K., Hida, S., Chiba, T., Murata, S., Sato, K., Takaoka, A., Yokochi, T., Oda, H., Tanaka, K., Nakamura, K., Taniguchi, T., 2000. Tcell- mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma. Nature 408, 600-605.
  • Takada, Y., Khuri, F.R., Aggarwal, B.B., 2004. Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis. J Biol Chem 279, 26287-26299.
  • Spergel, J.M., Mizoguchi, E., Oettgen, H., Bhan, A.K., Geha, R.S., 1999. Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis. J Clin Invest 103, 1103-1111.
  • Smolen, J.S., Aletaha, D., Koeller, M., Weisman, M.H., Emery, P., 2007. New therapies for treatment of rheumatoid arthritis. Lancet 370, 1861-1874.
  • Simmonds, R.E., Foxwell, B.M., 2008. Signalling, inflammation and arthritis: NF-kappaB and its relevance to arthritis and inflammation. Rheumatology. (Oxford). 47, 584-590.
  • Shin, T.Y., Kim, H.M., 2002. Inhibition of immediate-type allergic reactions by the aqueous extract of Salvia plebeia. Immunopharmacol. Immunotoxicol. 24, 303-314.
  • Shimada, Y., Takehara, K., Sato, S., 2004. Both Th2 and Th1 chemokines (TARC/CCL17, MDC/CCL22, and Mig/CXCL9) are elevated in sera from patients with atopic dermatitis. J Dermatol Sci 34, 201-208.
  • Shi, T.Y., Kim, H.M., 2002. Inhibition of immediate-type allergic reactions by the aqueous extract of Salvia plebeia. Immunopharmacol Immunotoxicol 24, 303-314.
  • Shah, P.P., Desai, P.R., Singh, M., 2012. Effect of oleic acid modified polymeric bilayered nanoparticles on percutaneous delivery of spantide II and ketoprofen. J Control Release 158, 336-345.
  • Schmid-Grendelmeier, P., Simon, D., Simon, H.U., Akdis, C.A., Wuthrich, B., 2001. Epidemiology, clinical features, and immunology of the "intrinsic" (non-IgEmediated) type of atopic dermatitis (constitutional dermatitis). Allergy 56, 841- 849.
  • Sato, S., Yamate, J., Hori, Y., Hatai, A., Nozawa, M., Sagai, M., 2005. Protective effect of polyphenol-containing azuki bean (Vigna angularis) seed coats on the renal cortex in streptozotocin-induced diabetic rats. J Nutr Biochem 16, 547-553.
  • Rose, L., Schneider, C., Stock, C., Zollner, T.M., Docke, W.D., 2012. Extended DNFB-induced contact hypersensitivity models display characteristics of chronic inflammatory dermatoses. Exp Dermatol 21, 25-31.
  • Reiner, S.L., 2007. Development in motion: Helper T cells at work. Cell 129, 33-36.
  • Quemeneur, L., Michallet, M.C., Ferraro-Peyret, C., Saint-Mezard, P., Benetiere, J., Ducluzeau, M.T., Nicolas, J.F., Revillard, J.P., 2003. Immunosuppressive antimetabolites inhibit induction of contact hypersensitivity while lymphoablative drugs also prevent its expression. Eur J Dermatol 13, 540- 547.
  • Quayle, J.A., Watson, F., Bucknall, R.C., Edwards, S.W., 1997. Neutrophils from the synovial fluid of patients with rheumatoid arthritis express the high affinity immunoglobulin G receptor, Fc gamma RI (CD64): role of immune complexes and cytokines in induction of receptor expression. Immunology 91, 266-273.
  • Qu, X.J., Xia, X., Wang, Y.S., Song, M.J., Liu, L.L., Xie, Y.Y., Cheng, Y.N., Liu, X.J., Qiu, L.L., Xiang, L., Gao, J.J., Zhang, X.F., Cui, S.X., 2009. Protective effects of Salvia plebeia compound homoplantaginin on hepatocyte injury. Food. Chem. Toxicol. 47, 1710-1715.
  • Qi, X.F., Teng, Y.C., Yoon, Y.S., Kim, D.H., Cai, D.Q., Lee, K.J., 2011. Reactive oxygen species are involved in the IFN-gamma-stimulated production of Th2 chemokines in HaCaT keratinocytes. J Cell Physiol 226, 58-65.
  • Parameswaran, N., Patial, S., 2010. Tumor necrosis factor-alpha signaling in macrophages. Crit Rev Eukaryot Gene Expr 20, 87-103.
  • Oyoshi, M.K., He, R., Kumar, L., Yoon, J., Geha, R.S., 2009b. Cellular and molecular mechanisms in atopic dermatitis. Adv Immunol 102, 135-226.
  • Oyoshi, M.K., He, R., Kumar, L., Yoon, J., Geha, R.S., 2009a. Cellular and Molecular Mechanisms in Atopic Dermatitis. Adv Immunol 102, 135-226.
  • Oyoshi, M.K., He, R., Kumar, L., Yoon, J., Geha, R.S., 2009. Cellular and molecular mechanisms in atopic dermatitis. Adv Immunol 102, 135-226.
  • Oka, T., Rios, E.J., Tsai, M., Kalesnikoff, J., Galli, S.J., 2013. Rapid desensitization induces internalization of antigen-specific IgE on mouse mast cells. J Allergy Clin Immunol.
  • Ohsawa, Y., Hirasawa, N., 2012. The antagonism of histamine H1 and H4 receptors ameliorates chronic allergic dermatitis via anti-pruritic and antiinflammatory effects in NC/Nga mice. Allergy.
  • Oh, H.M., Lee, S.W., Yun, B.R., Hwang, B.S., Kim, S.N., Park, C.S., Jeoung, S.H., Kim, H.K., Lee, W.S., Rho, M.C., 2014. Vigna angularis inhibits IL-6- induced cellular signalling and ameliorates collagen-induced arthritis. Rheumatology (Oxford) 53, 56-64.
  • Oguro, T., Liu, J., Klaassen, C.D., Yoshida, T., 1998. Inhibitory effect of oleanolic acid on 12-O-tetradecanoylphorbol-13-acetate-induced gene expression in mouse skin. Toxicol Sci 45, 88-93.
  • Nugroho, A., Kim, M.H., Choi, J., Baek, N.I., Park, H.J., 2012a. In vivo sedative and gastroprotective activities of Salvia plebeia extract and its composition of polyphenols. Arch. Pharm. Res. 35, 1403-1411.
  • Nugroho, A., Kim, M.H., Choi, J., Baek, N.I., Park, H.J., 2012. In vivo sedative and gastroprotective activities of Salvia plebeia extract and its composition of polyphenols. Arch Pharm Res 35, 1403-1411.
  • Novak, N., Koch, S., Allam, J.P., Bieber, T., 2010. Dendritic cells: Bridging innate and adaptive immunity in atopic dermatitis. J Allergy Clin Immun 125, 50-59.
  • Novak, N., 2009. New insights into the mechanism and management of allergic diseases: atopic dermatitis. Allergy 64, 265-275.
  • Nograles, K.E., Zaba, L.C., Shemer, A., Fuentes-Duculan, J., Cardinale, I., Kikuchi, T., Ramon, M., Bergman, R., Krueger, J.G., Guttman-Yassky, E., 2009. IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells. J Allergy Clin Immunol 123, 1244-1252 e1242.
  • Neis, M.M., Peters, B., Dreuw, A., Wenzel, J., Bieber, T., Mauch, C., Krieg, T., Stanzel, S., Heinrich, P.C., Merk, H.F., Bosio, A., Baron, J.M., Hermanns, H.M., 2006. Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis. J Allergy Clin Immunol 118, 930-937.
  • National Institute of Environmental Health Sciences (NIEHS); the Murine Local Lymph Node Assay: a Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds, report now available. Public Health Service. Fed Regist 64, 14006-14007.
  • Nam, E.J., Kang, J.H., Sung, S., Sa, K.H., Kim, K.H., Seo, J.S., Kim, J.H., Han, S.W., Kim, I.S., Kang, Y.M., 2013. A MMP1-cleavable composite peptide derived from betaig-h3 potently inhibits chronic inflammatory arthritis. Arthritis. Rheum. 65, 1753-1763.
  • Nam, E.J., Kang, J.H., Sung, S., Sa, K.H., Kim, K.H., Seo, J.S., Kim, J.H., Han, S.W., Kim, I.S., Kang, Y.M., 2013. A MMP1-cleavable composite peptide derived from betaig-h3 potently inhibits chronic inflammatory arthritis. Arthritis Rheum.
  • Nakayama, T., Hieshima, K., Nagakubo, D., Sato, E., Nakayama, M., Kawa, K., Yoshie, O., 2004. Selective induction of Th2-attracting chemokines CCL17 and CCL22 in human B cells by latent membrane protein 1 of Epstein-Barr virus. J Virol 78, 1665-1674.
  • Nader, M.A., 2013. Caffeic acid phenethyl ester attenuates IgE-induced immediate allergic reaction. Inflammopharmacology 21, 169-176.
  • Muller-Ladner, U., Pap, T., Gay, R.E., Neidhart, M., Gay, S., 2005. Mechanisms of disease: the molecular and cellular basis of joint destruction in rheumatoid arthritis. Nature Clinical Practice Rheumatology 1, 102-110.
  • Mukherjee, P., Wu, B., Mayton, L., Kim, S.H., Robbins, P.D., Wooley, P.H., 2003. TNF receptor gene therapy results in suppression of IgG2a anticollagen antibody in collagen induced arthritis. Ann Rheum Dis 62, 707-714.
  • Mukai, Y., Sato, S., 2011. Polyphenol-containing azuki bean (Vigna angularis) seed coats attenuate vascular oxidative stress and inflammation in spontaneously hypertensive rats. J Nutr Biochem 22, 16-21.
  • Medzhitov, R., 2008. Origin and physiological roles of inflammation. Nature 454, 428-435.
  • McInnes, I.B., Schett, G., 2011. The pathogenesis of rheumatoid arthritis. N Engl J Med 365, 2205-2219.
  • McInnes, I.B., Schett, G., 2007. Cytokines in the pathogenesis of rheumatoid arthritis. Nat Rev Immunol 7, 429-442.
  • Malemud, C.J., 2013. Intracellular Signaling Pathways in Rheumatoid Arthritis. J Clin Cell Immunol 4, 160.
  • Majithia, V., Geraci, S.A., 2007. Rheumatoid arthritis: Diagnosis and management. American Journal of Medicine 120, 936-939.
  • Lubberts, E., Koenders, M.I., van den Berg, W.B., 2005. The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models. Arthritis Res Ther 7, 29-37.
  • Lubberts, E., 2014. Role of T lymphocytes in the development of rheumatoid arthritis. Implications for treatment. Curr Pharm Des.
  • Lu, Y., Foo, L.Y., 2002. Polyphenolics of Salvia--a review. Phytochemistry 59, 117-140.
  • Lin, G., Li, J., 2010. Elevation of serum IgG subclass concentration in patients with rheumatoid arthritis. Rheumatol. Int. 30, 837-840.
  • Leung, D.Y.M., Boguniewicz, M., Howell, M.D., Nomura, I., Hamid, O.A., 2004. New insights into atopic dermatitis. J Clin Invest 113, 651-657.
  • Leung, D.Y., Bieber, T., 2003. Atopic dermatitis. Lancet 361, 151-160.
  • Lee, S., Yun, H.S., Kim, S.H., 2011. The comparative effects of mesoporous silica nanoparticles and colloidal silica on inflammation and apoptosis. Biomaterials 32, 9434-9443.
  • Lee, S., Suk, K., Kim, I.K., Jang, I.S., Park, J.W., Johnson, V.J., Kwon, T.K., Choi, B.J., Kim, S.H., 2008. Signaling pathways of bisphenol A-induced apoptosis in hippocampal neuronal cells: role of calcium-induced reactive oxygen species, mitogen-activated protein kinases, and nuclear factor-kappaB. J Neurosci Res 86, 2932-2942.
  • Lee, J.Y., Moon, H., Kim, C.J., 2010. Effects of hydroxy pentacyclic triterpene acids from Forsythia viridissima on asthmatic responses to ovalbumin challenge in conscious guinea pigs. Biol Pharm Bull 33, 230-237.
  • Lee, H.K., Nam, G.W., Kim, S.H., Lee, S.H., 2006. Phytocomponents of triterpenoids, oleanolic acid and ursolic acid, regulated differently the processing of epidermal keratinocytes via PPAR-alpha pathway. Exp Dermatol 15, 66-73.
  • Kwon, H.K., Lee, C.G., So, J.S., Chae, C.S., Hwang, J.S., Sahoo, A., Nam, J.H., Rhee, J.H., Hwang, K.C., Im, S.H., 2010. Generation of regulatory dendritic cells and CD4+Foxp3+ T cells by probiotics administration suppresses immune disorders. Proc Natl Acad Sci U S A 107, 2159-2164.
  • Kwon, D.J., Bae, Y.S., Ju, S.M., Goh, A.R., Youn, G.S., Choi, S.Y., Park, J., 2012. Casuarinin suppresses TARC/CCL17 and MDC/CCL22 production via blockade of NF-kappaB and STAT1 activation in HaCaT cells. Biochem Biophys Res Commun 417, 1254-1259.
  • Kumar, S., Blake, S.M., Emery, J.G., 2001. Intracellular signaling pathways as a target for the treatment of rheumatoid arthritis. Curr. Opin. Pharmacol. 1, 307- 313.
  • Kumar, P., Banik, S., 2013. Pharmacotherapy options in rheumatoid arthritis. Clin Med Insights Arthritis Musculoskelet Disord 6, 35-43.
  • Komutarin, T., Azadi, S., Butterworth, L., Keil, D., Chitsomboon, B., Suttajit, M., Meade, B.J., 2004. Extract of the seed coat of Tamarindus indica inhibits nitric oxide production by murine macrophages in vitro and in vivo. Food and Chemical Toxicology 42, 649-658.
  • Komatsu, T., Sakurada, T., 2012. Comparison of the efficacy and skin permeability of topical NSAID preparations used in Europe. Eur. J. Pharm. Sci. 47, 890-895.
  • Komatsu, N., Takayanagi, H., 2012. Inflammation and bone destruction in arthritis: synergistic activity of immune and mesenchymal cells in joints. Front Immunol 3, 77.
  • Kolls, J.K., McCray, P.B., Jr., Chan, Y.R., 2008. Cytokine-mediated regulation of antimicrobial proteins. Nat Rev Immunol 8, 829-835.
  • Koga, C., Kabashima, K., Shiraishi, N., Kobayashi, M., Tokura, Y., 2008. Possible pathogenic role of Th17 cells for atopic dermatitis. J Invest Dermatol 128, 2625- 2630.
  • Klunker, S., Trautmann, A., Akdis, M., Verhagen, J., Schmid-Grendelmeier, P., Blaser, K., Akdis, C.A., 2003. A second step of chemotaxis after transendothelial migration: keratinocytes undergoing apoptosis release IFN-gamma-inducible protein 10, monokine induced by IFN-gamma, and IFN-gamma-inducible alphachemoattractant for T cell chemotaxis toward epidermis in atopic dermatitis. J Immunol 171, 1078-1084.
  • King, M.A., 1997. Pocket companion to robbins pathologic basis of disease - Robbins,SL, Cotran,RS, Kumar,V. N&Hc-Perspectives on Community 18, 99-99.
  • Kim, S.Y., Sohn, E.J., Kim, D.W., Jeong, H.J., Kim, M.J., Kang, H.W., Shin, M.J., Ahn, E.H., Kwon, S.W., Kim, Y.N., Kwon, H.J., Kim, T.Y., Lee, K.S., Park, J., Eum, W.S., Choi, S.Y., 2011. Transduced PEP-1-FK506BP ameliorates atopic dermatitis in NC/Nga mice. J Invest Dermatol 131, 1477-1485.
  • Kim, S.H., Lee, S., Suk, K., Bark, H., Jun, C.D., Kim, D.K., Choi, C.H., Yoshimura, T., 2007. Discoidin domain receptor 1 mediates collagen-induced nitric oxide production in J774A.1 murine macrophages. Free Radic Biol Med 42, 343-352.
  • Kim, J.Y., Cheon, Y.H., Oh, H.M., Rho, M.C., Erkhembaatar, M., Kim, M.S., Lee, C.H., Kim, J.J., Choi, M.K., Yoon, K.H., Lee, M.S., Oh, J., 2014. Oleanolic acid acetate inhibits osteoclast differentiation by downregulating PLCgamma2-Ca(2+)-NFATc1 signaling, and suppresses bone loss in mice. Bone 60, 104-111.
  • Kay, J., Calabrese, L., 2004. The role of interleukin-1 in the pathogenesis of rheumatoid arthritis. Rheumatology. (Oxford). 43 Suppl 3, iii2-iii9.
  • Kawakami, T., Ando, T., Kimura, M., Wilson, B.S., Kawakami, Y., 2009. Mast cells in atopic dermatitis. Curr Opin Immunol 21, 666-678.
  • Kapil, A., Sharma, S., 1995. Effect of oleanolic acid on complement in adjuvantand carrageenan-induced inflammation in rats. J Pharm Pharmacol 47, 585- 587.
  • Kanda, N., Shimizu, T., Tada, Y., Watanabe, S., 2007. IL-18 enhances IFN-gamma188 induced production of CXCL9, CXCL10, and CXCL11 in human keratinocytes. Eur J Immunol 37, 338-350.
  • Kakinuma, T., Nakamura, K., Wakugawa, M., Mitsui, H., Tada, Y., Saeki, H., Torii, H., Komine, M., Asahina, A., Tamaki, K., 2002. Serum macrophage-derived chemokine (MDC) levels are closely related with the disease activity of atopic dermatitis. Clin Exp Immunol 127, 270-273.
  • Kaiko, G.E., Foster, P.S., 2011. New insights into the generation of Th2 immunity and potential therapeutic targets for the treatment of asthma. Curr Opin Allergy Cl 11, 39-45.
  • Juarranz, Y., Abad, C., Martinez, C., Arranz, A., Gutierrez-Canas, I., Rosignoli, F., Gomariz, R.P., Leceta, J., 2005. Protective effect of vasoactive intestinal peptide on bone destruction in the collagen-induced arthritis model of rheumatoid arthritis. Arthritis. Res. Ther. 7, R1034-1045.
  • Jin, X.F., Lu, Y.H., Wei, D.Z., Wang, Z.T., 2008. Chemical fingerprint and quantitative analysis of Salvia plebeia R.Br. by high-performance liquid chromatography. J. Pharm. Biomed. Anal. 48, 100-104.
  • Jin, H., Oyoshi, M.K., Le, Y., Bianchi, T., Koduru, S., Mathias, C.B., Kumar, L., Le Bras, S., Young, D., Collins, M., Grusby, M.J., Wenzel, J., Bieber, T., Boes, M., Silberstein, L.E., Oettgen, H.C., Geha, R.S., 2009. IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice. J Clin Invest 119, 47-60.
  • Jin, H., Kumar, L., Mathias, C., Zurakowski, D., Oettgen, H., Gorelik, L., Geha, R., 2009. Toll-like receptor 2 is important for the T(H)1 response to cutaneous sensitization. J Allergy Clin Immunol 123, 875-882 e871.
  • Jiang, H., Hener, P., Li, J., Li, M., 2012. Skin thymic stromal lymphopoietin promotes airway sensitization to inhalant house dust mites leading to allergic asthma in mice. Allergy 67, 1078-1082.
  • Jeong, C.W., Ahn, K.S., Rho, N.K., Park, Y.D., Lee, D.Y., Lee, J.H., Lee, E.S., Yang, J.M., 2003. Differential in vivo cytokine mRNA expression in lesional skin of intrinsic vs. extrinsic atopic dermatitis patients using semiquantitative RT-PCR. Clin Exp Allergy 33, 1717-1724.
  • Jahnz-Rozyk, K., Targowski, T., Paluchowska, E., Owczarek, W., Kucharczyk, A., 2005. Serum thymus and activation-regulated chemokine, macrophage-derived chemokine and eotaxin as markers of severity of atopic dermatitis. Allergy 60, 685-688.
  • Iwaoka, E., Oku, H., Iinuma, M., Ishiguro, K., 2010. Allergy-preventive effects of the flowers of Impatiens textori. Biol Pharm Bull 33, 714-716.
  • Itoh, T., Umekawa, H., Furuichi, Y., 2005. Potential ability of hot water adzuki (Vigna angularis) extracts to inhibit the adhesion, invasion, and metastasis of murine B16 melanoma cells. Biosci Biotechnol Biochem 69, 448-454.
  • Irmler, I.M., Opfermann, T., Gebhardt, P., Gajda, M., Brauer, R., Saluz, H.P., Kamradt, T., 2010. In vivo molecular imaging of experimental joint inflammation by combined (18)F-FDG positron emission tomography and computed tomography. Arthritis Res Ther 12, R203.
  • Hwang, J.K., Noh, E.M., Moon, S.J., Kim, J.M., Kwon, K.B., Park, B.H., You, Y.O., Hwang, B.M., Kim, H.J., Kim, B.S., Lee, S.J., Kim, J.S., Lee, Y.R., 2013. Emodin suppresses inflammatory responses and joint destruction in collageninduced arthritic mice. Rheumatology. (Oxford). 52, 1583-1591.
  • He, R., Geha, R.S., 2010. Thymic stromal lymphopoietin. Ann N Y Acad Sci 1183, 13-24.
  • Guttman-Yassky, E., Nograles, K.E., Krueger, J.G., 2011. Contrasting pathogenesis of atopic dermatitis and psoriasis--part I: clinical and pathologic concepts. J Allergy Clin Immunol 127, 1110-1118.
  • Gu, L.W., Weng, X.C., 2001. Antioxidant activity and components of Salvia plebeia R.Br. - a Chinese herb. Food. Chem. 73, 299-305.
  • Greaves, M.W., 2005. Antihistamines in dermatology. Skin Pharmacol Physiol 18, 220-229.
  • Gittler, J.K., Shemer, A., Suarez-Farinas, M., Fuentes-Duculan, J., Gulewicz, K.J., Wang, C.Q., Mitsui, H., Cardinale, I., de Guzman Strong, C., Krueger, J.G., Guttman-Yassky, E., 2012. Progressive activation of T(H)2/T(H)22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis. J Allergy Clin Immunol 130, 1344-1354.
  • Girolomoni, G., Pastore, S., 2001. Epithelial cells and atopic diseases. Curr Allergy Asthma Rep 1, 481-482.
  • Giner-Larza, E.M., Manez, S., Recio, M.C., Giner, R.M., Prieto, J.M., Cerda52 Nicolas, M., Rios, J.L., 2001. Oleanonic acid, a 3-oxotriterpene from Pistacia, inhibits leukotriene synthesis and has anti-inflammatory activity. Eur J Pharmacol 428, 137-143.
  • Giner-Larza, E.M., Manez, S., Recio, M.C., Giner, R.M., Prieto, J.M., Cerda- Nicolas, M., Rios, J.L., 2001. Oleanonic acid, a 3-oxotriterpene from Pistacia, inhibits leukotriene synthesis and has anti-inflammatory activity. Eur J Pharmacol 428, 137-143.
  • Fujita, H., Shemer, A., Suarez-Farinas, M., Johnson-Huang, L.M., Tintle, S., Cardinale, I., Fuentes-Duculan, J., Novitskaya, I., Carucci, J.A., Krueger, J.G., Guttman-Yassky, E., 2011. Lesional dendritic cells in patients with chronic atopic dermatitis and psoriasis exhibit parallel ability to activate Tcell subsets. Journal of Allergy and Clinical Immunology 128, 574-U216.
  • Frohlich, A., Kisielow, J., Schmitz, I., Freigang, S., Shamshiev, A.T., Weber, J., Marsland, B.J., Oxenius, A., Kopf, M., 2009. IL-21R on T Cells Is Critical for Sustained Functionality and Control of Chronic Viral Infection. Science 324, 1576-1580.
  • Firestein, G.S., 2003. Evolving concepts of rheumatoid arthritis. Nature 423, 356- 361.
  • Finkelman, F.D., Boyce, J.A., Vercelli, D., Rothenberg, M.E., 2010. Key advances in mechanisms of asthma, allergy, and immunology in 2009. J Allergy Clin Immun 125, 312-318.
  • Eyerich, S., Eyerich, K., Pennino, D., Carbone, T., Nasorri, F., Pallotta, S., Cianfarani, F., Odorisio, T., Traidl-Hoffmann, C., Behrendt, H., Durham, S.R., Schmidt-Weber, C.B., Cavani, A., 2009. Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. J Clin Invest 119, 3573-3585.
  • Duhen, T., Geiger, R., Jarrossay, D., Lanzavecchia, A., Sallusto, F., 2009. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol 10, 857-863.
  • Doodes, P.D., Cao, Y., Hamel, K.M., Wang, Y., Rodeghero, R.L., Mikecz, K., Glant, T.T., Iwakura, Y., Finnegan, A., 2010. IFN-gamma regulates the requirement for IL-17 in proteoglycan-induced arthritis. J Immunol 184, 1552-1559.
  • Dokmeci, E., Herrick, C.A., 2008. The immune system and atopic dermatitis. Semin Cutan Med Surg 27, 138-143.
  • Dinkova-Kostova, A.T., Liby, K.T., Stephenson, K.K., Holtzclaw, W.D., Gao, X., Suh, N., Williams, C., Risingsong, R., Honda, T., Gribble, G.W., Sporn, M.B., Talalay, P., 2005. Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress. Proc Natl Acad Sci U S A 102, 4584-4589.
  • Dhar, A., Young, M.R., Colburn, N.H., 2002. The role of AP-1, NF-kappaB and ROS/NOS in skin carcinogenesis: the JB6 model is predictive. Mol Cell Biochem 234-235, 185-193.
  • Dayer, J.M., Choy, E., 2010. Therapeutic targets in rheumatoid arthritis: the interleukin-6 receptor. Rheumatology. (Oxford). 49, 15-24.
  • Dai, Y., Hang, B.Q., Li, P.Z., Tan, L.W., 1989. [Effects of oleanolic acid on immune system and type I allergic reaction]. Zhongguo Yao Li Xue Bao 10, 381-384.
  • Dai, X., Sayama, K., Tohyama, M., Shirakata, Y., Hanakawa, Y., Tokumaru, S., Yang, L., Hirakawa, S., Hashimoto, K., 2011. Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes. J Allergy Clin Immunol 127, 806-814 e801-804.
  • Combe, B., 2011. The new classification criteria for rheumatoid arthritis and their impact on therapeutic decisions. Joint Bone Spine 78, 539-541.
  • Collantes, T.M., Rho, M.C., Kwon, H.J., Jung, B.G., Alfajaro, M.M., Kim, D.S., Kim, H.J., Hosmillo, M., Park, J.G., Son, K.Y., Park, S.I., Kang, M.I., Park, S.J., Lee, S.W., Lee, W.S., Cho, K.O., 2012. Azuki bean (Vigna angularis) extract inhibits the development of experimentally induced atopic dermatitislike skin lesions in NC/Nga mice. Food Chemistry 132, 1269-1275.
  • Coaccioli, S., 2011. Ketoprofen 2.5% gel: a clinical overview. Eur. Rev. Med. Pharmacol. Sci. 15, 943-949.
  • Choi, J.K., Oh, H.M., Lee, S., Park, J.W., Khang, D., Lee, S.W., Lee, W.S., Rho, M.C., Kim, S.H., 2013. Oleanolic acid acetate inhibits atopic dermatitis and allergic contact dermatitis in a murine model. Toxicol Appl Pharmacol 269, 72-80.
  • Choi, J.K., Oh, H.M., Lee, S., Kwon, T.K., Shin, T.Y., Rho, M.C., Kim, S.H., 2014. Salvia plebeia Suppresses Atopic Dermatitis-Like Skin Lesions. Am J Chin Med 42, 967-985.
  • Choi, J.K., Kim, S.H., 2013. Rutin suppresses atopic dermatitis and allergic contact dermatitis. Exp Biol Med (Maywood) 238, 410-417.
  • Choi, E.J., Lee, S., Kim, H.H., Singh, T.S., Choi, J.K., Choi, H.G., Suh, W.M., Lee, S.H., Kim, S.H., 2011b. Suppression of dust mite extract and 2,4- dinitrochlorobenzene-induced atopic dermatitis by the water extract of Lindera obtusiloba. J Ethnopharmacol 137, 802-807.
  • Choi, E.J., Lee, S., Hwang, J.S., Im, S.H., Jun, C.D., Lee, H.S., Kim, S.H., 2011a. DA-9601 suppresses 2, 4-dinitrochlorobenzene and dust mite extract-induced atopic dermatitis-like skin lesions. Int Immunopharmacol 11, 1260-1264.
  • Cho, Y.G., Cho, M.L., Min, S.Y., Kim, H.Y., 2007. Type II collagen autoimmunity in a mouse model of human rheumatoid arthritis. Autoimmun Rev 7, 65-70.
  • Burrage, P.S., Mix, K.S., Brinckerhoff, C.E., 2006. Matrix metalloproteinases: role in arthritis. Front Biosci 11, 529-543.
  • Brennan, F.M., McInnes, I.B., 2008. Evidence that cytokines play a role in rheumatoid arthritis. J Clin Invest 118, 3537-3545.
  • Brandt, E.B., Sivaprasad, U., 2011. Th2 Cytokines and Atopic Dermatitis. J Clin Cell Immunol 2.
  • Bottini, N., Firestein, G.S., 2013. Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors. Nat. Rev. Rheumatol. 9, 24-33.
  • Bottini, N., Firestein, G.S., 2013. Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors. Nat Rev Rheumatol 9, 24-33. Brand, D.D., Latham, K.A., Rosloniec, E.F., 2007. Collagen-induced arthritis. Nat Protoc 2, 1269-1275.
  • Boller, S., Soldi, C., Marques, M.C., Santos, E.P., Cabrini, D.A., Pizzolatti, M.G., Zampronio, A.R., Otuki, M.F., 2010. Anti-inflammatory effect of crude extract and isolated compounds from Baccharis illinita DC in acute skin inflammation. J Ethnopharmacol 130, 262-266.
  • Boguniewicz, M., Leung, D.Y.M., 2010. Recent insights into atopic dermatitis and implications for management of infectious complications. J Allergy Clin Immun 125, 4-13.
  • Blackwell, T.S., Blackwell, T.R., Christman, J.W., 1997. Impaired activation of nuclear factor-kappaB in endotoxin-tolerant rats is associated with downregulation of chemokine gene expression and inhibition of neutrophilic lung inflammation. J Immunol 158, 5934-5940.
  • Bieber, T., 2010. Atopic dermatitis. Ann Dermatol 22, 125-137.
  • Bevaart, L., Vervoordeldonk, M.J., Tak, P.P., 2010. Evaluation of therapeutic targets in animal models of arthritis: how does it relate to rheumatoid arthritis? Arthritis Rheum 62, 2192-2205.
  • Beckers, C., Ribbens, C., Andre, B., Marcelis, S., Kaye, O., Mathy, L., Kaiser, M.J., Hustinx, R., Foidart, J., Malaise, M.G., 2004. Assessment of disease activity in rheumatoid arthritis with (18)F-FDG PET. J Nucl Med 45, 956- 964.
  • Bartok, B., Firestein, G.S., 2010. Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis. Immunol Rev 233, 233-255.
  • Baek, S.Y., Lee, J., Lee, D.G., Park, M.K., Kwok, S.K., Cho, M.L., Park, S.H., 2014. Ursolic acid ameliorates autoimmune arthritis via suppression of Th17 and B cell differentiation. Acta Pharmacol Sin 35, 1177-1187.
  • Bae, Y., Lee, S., Kim, S.H., 2011. Chrysin suppresses mast cell-mediated allergic inflammation: involvement of calcium, caspase-1 and nuclear factor-kappaB. Toxicol Appl Pharmacol 254, 56-64.
  • Asquith, D.L., Miller, A.M., McInnes, I.B., Liew, F.Y., 2009. Animal models of rheumatoid arthritis. Eur J Immunol 39, 2040-2044.
  • Arbabi, S., Maier, R.V., 2002. Mitogen-activated protein kinases. Crit Care Med 30, S74-S79.
  • Anderson, S.E., Siegel, P.D., Meade, B.J., 2011. The LLNA: A Brief Review of Recent Advances and Limitations. J Allergy (Cairo) 2011, 424203.
  • Akdis, C.A., Akdis, M., Bieber, T., Bindslev-Jensen, C., Boguniewicz, M., Eigenmann, P., Hamid, Q., Kapp, A., Leung, D.Y., Lipozencic, J., Luger, T.A., Muraro, A., Novak, N., Platts-Mills, T.A., Rosenwasser, L., Scheynius, A., Simons, F.E., Spergel, J., Turjanmaa, K., Wahn, U., Weidinger, S., Werfel, T., Zuberbier, T., 2006. Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. J Allergy Clin Immunol 118, 152-169.
  • Ahmed, S., Riegsecker, S., Beamer, M., Rahman, A., Bellini, J.V., Bhansali, P., Tillekeratne, L.M., 2013. Largazole, a class I histone deacetylase inhibitor, enhances TNF-alpha-induced ICAM-1 and VCAM-1 expression in rheumatoid arthritis synovial fibroblasts. Toxicol. Appl. Pharmacol. 270, 87- 96.
  • Adenuga, D., Woolhiser, M.R., Gollapudi, B.B., Boverhof, D.R., 2012. Differential gene expression responses distinguish contact and respiratory sensitizers and nonsensitizing irritants in the local lymph node assay. Toxicol Sci 126, 413-425.