박사

인플루엔자 A 바이러스의 NS 조각 변형에 의한 병원성 및 감염 혹은 사백신에 의한 교차 방어 효능 검증

박수진 2015년
논문상세정보
' 인플루엔자 A 바이러스의 NS 조각 변형에 의한 병원성 및 감염 혹은 사백신에 의한 교차 방어 효능 검증' 의 주제별 논문영향력
논문영향력 선정 방법
논문영향력 요약
주제
  • h5n1
  • influenza virus
  • ns segments
  • ns 조각
  • pathogencity
  • vaccination
  • 백신
  • 병원성
  • 인플루엔자 바이러스
동일주제 총논문수 논문피인용 총횟수 주제별 논문영향력의 평균
209 0

0.0%

' 인플루엔자 A 바이러스의 NS 조각 변형에 의한 병원성 및 감염 혹은 사백신에 의한 교차 방어 효능 검증' 의 참고문헌

  • Zhang,D.G.,W.Z.Li,G.F.Wang,Y.Su,J.Zeng,C.Zhang,X.X. Zeng,X.X.Chen,Y.X.Xu,andK.S.Li(2010),"Heterologous SH3-p85beta inhibits influenza A virus replication," Virology Journal,7,170.
  • Zamarin,D.,A.Garcia-Sastre,X.Xiao,R.Wang,andP.Palese(2005), "Influenza virus PB1-F2 protein induces cell death through mitochondrialANT3andVDAC1,"PlosPathogens,1,e4.
  • WorldHealthOrganization(10-2014),"Cumulativenumberofconfirmed human cases ofavian influenza A/(H5N1)reported to WHO," http://www.who.int/influenza/human_animal_interface/EN_GIP_20 141002CumulativeNumberH5N1cases.pdf?ua=1
  • Wei,L.,M.R.Sandbulte,P.G.Thomas,R.J.Webby,R.Homayouni, and L.M.Pfeffer(4-28-2006),"NFkappaB negatively regulates interferon-induced gene expression and anti-influenza activity," JournalofBiologicalChemistry,281,11678-11684.
  • Webster,R.G.,W.J.Bean,O.T.Gorman,T.M.Chambers,and Y. Kawaoka(1992),"Evolution andecology ofinfluenzaA viruses," MicrobiologicalReviews,56,152-179.
  • Wang,T.T.,G.S.Tan,R.Hai,N.Pica,L.Ngai,D.C.Ekiert,I.A. Wilson, A. Garcia-Sastre, T. M. Moran, and P. Palese(11-2-2010),"Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinctviralsubtypes,"Proceedings ofthe NationalAcademy ofSciencesoftheUnitedStatesofAmerica,107,18979-18984.
  • Us,D.(2008),"Cytokinestorm inavianinfluenza,"MikrobiyolojiBulteni, 42,365-380.
  • Tompkins,S.M.,Y.Lin,G.P.Leser,K.A.Kramer,D.L.Haas,E. W.Howerth,J.Xu,M.J.Kennett,R.K.Durbin,J.E.Durbin, R.Tripp,R.A.Lamb,and B.He(5-25-2007),"Recombinant parainfluenza virus 5 (PIV5)expressing the influenza A virus hemagglutinin provides immunity in mice to influenza A virus challenge,"Virology,362,139-150.
  • Suguitan,A.L.,Jr.,J.McAuliffe,K.L.Mills,H.Jin,G.Duke,B.Lu, C.J.Luke,B.Murphy,D.E.Swayne,G.Kemble,and K. Subbarao(2006),"Live,attenuated influenza A H5N1 candidate vaccines provide broad cross-protection in mice and ferrets," PlosMedicine,3,e360-
  • Stevens,J.,A.L.Corper,C.F.Basler,J.K.Taubenberger,P.Palese, andI.A.Wilson(3-19-2004),"Structureoftheuncleavedhuman H1 hemagglutinin from the extinct 1918 influenza virus," Science,303,1866-1870.
  • Sprenger,H.,R.G.Meyer,A.Kaufmann,D.Bussfeld,E.Rischkowsky, and D.Gemsa(9-1-1996),"Selective induction ofmonocyteand not neutrophil-attracting chemokines after influenza A virus infection,"JournalofExperimentalMedicine,184,1191-1196.
  • Song,M.S.,T.K.Oh,P.N.Pascua,H.J.Moon,J.H.Lee,Y.H. Baek,K.J.Woo,Y.Yoon,M.H.Sung,H.Poo,C.J.Kim,and Y.K.Choi(5-21-2009),"Investigation ofthebiologicalindicator for vaccine efficacy againsthighly pathogenic avian influenza (HPAI)H5N1viruschallengein miceandferrets,"Vaccine,27, 3145-3152.
  • Shin,Y.K.,Y.Li,Q.Liu,D.H.Anderson,L.A.Babiuk,and Y. Zhou(2007),"SH3 binding motif 1 in influenza A virus NS1 protein isessentialforPI3K/Aktsignaling pathway activation," JournalofVirology,81,12730-12739.
  • Shi,M.,B.W.Jagger,H.M.Wise,P.Digard,E.C.Holmes,andJ.K. Taubenberger(2012), "Evolutionary conservation of the PA-X openreading frameinsegment3ofinfluenzaA virus,"Journal ofVirology,86,12411-12413.
  • Seo,S.H.,E.Hoffmann,andR.G.Webster(2004),"TheNS1geneof H5N1influenzavirusescircumventsthehostanti-viralcytokine responses,"VirusResearch,103,107-113.
  • Schulman,J.L.and E.D.Kilbourne(1965),"Induction ofpartialof specificheterotypicimmunity inmiceby asingleinfectionwith influenzaA virus,"JournalofBacteriology,89,170-174.
  • Salomon,R.,E.Hoffmann,andR.G.Webster(7-24-2007),"Inhibitionof the cytokine response does not protect against lethalH5N1 influenza infection," Proceedings ofthe NationalAcademy of SciencesoftheUnitedStatesofAmerica,104,12479-12481.
  • Sakabe,S.,K.Iwatsuki-Horimoto,T.Horimoto,C.A.Nidom,MtLe, R.Takano,R.Kubota-Koketsu,Y.Okuno,M.Ozawa,and Y. Kawaoka(2010), "A cross-reactive neutralizing monoclonal antibody protects mice from H5N1 and pandemic (H1N1)2009 virusinfection,"AntiviralResearch,88,249-255.
  • Robb,N.C.,M.Smith,F.T.Vreede,and E.Fodor(2009),"NS2/NEP protein regulates transcription and replication ofthe influenza virus RNA genome," Journal of General Virology, 90, 1398-1407.
  • Ritchey,M.B.,P.Palese,and J.L.Schulman(1976),"Mapping ofthe influenza virus genome.III.Identification ofgenes coding for nucleoprotein, membrane protein, and nonstructural protein," JournalofVirology,,20,307-313.
  • Reed,L.J.A.M.H.(1938),"A simple method of estimating 50% endpoints,"AmercanJournalofHygiene,27,493-497.
  • Raynard,R.S.,A.G.Murray,and A.Gregory(9-12-2001),"Infectious salmon anaemia virus in wild fish from Scotland,"Disease of AquaticOrganisms,46,93-100.
  • REED,L.J.A.M.H.(1938),"A simple method ofestimating 50% endpoints,"AmericanJournalofHygiene,27,493-497.
  • Petri,T.,S.Patterson,andN.J.Dimmock(1982),"Polymorphism ofthe NS1 proteins oftype A influenza virus," JournalofGeneral Virology,61(Pt2),217-231.
  • Paterson,D.and E.Fodor(2012),"Emerging rolesfortheinfluenzaA virus nuclear export protein (NEP)," Plos Pathogens, 8, e1003019.
  • Pascua,P.N.,M.S.Song,J.H.Lee,K.J.Park,H.I.Kwon,Y.H. Baek,S.P.Hong,J.B.Rho,C.J.Kim,H.Poo,T.S.Ryoo,M. H.Sung,andY.K.Choi(2009),"Evaluation oftheefficacy and cross-protectivity ofrecenthuman and swine vaccines against thepandemic(H1N1)2009virusinfection,"PlosOne,4,e8431.
  • Pappaioanou,M.(2009),"Highly pathogenicH5N1avian influenzavirus: cause of the next pandemic?," Comparative Immunology MicrobiologyandInfectiousDisease,32,287-300.
  • Palese P., Tobita K., Ueda M., Compans R. W.(1974), "Characterizationoftemperaturesensitiveinfluenzavirusmutants defectiveinneuraminidase,"Virology,61:397-410.
  • Osterhaus,A.D.,G.F.Rimmelzwaan,B.E.Martina,T.M.Bestebroer, and R.A.Fouchier(5-12-2000),"Influenza B virus in seals," Science,288,1051-1053.
  • O'Neill,R.E.,J.Talon,and P.Palese(1-2-1998),"Theinfluenzavirus NEP (NS2 protein) mediates the nuclear export of viral ribonucleoproteins,"EMBO Journal,17,288-296.
  • Noah,D.L.,K.Y.Twu,andR.M.Krug(3-15-2003),"Cellularantiviral responses against influenza A virus are countered at the posttranscriptional level by the viral NS1A protein via its binding toacellularprotein required forthe3'end processing ofcellularpre-mRNAS,"Virology,307,386-395.
  • Neumann,G.,T.Watanabe,H.Ito,S.Watanabe,H.Goto,P.Gao,M. Hughes,D.R.Perez,R.Donis,E.Hoffmann,G.Hobom,andY. Kawaoka(8-3-1999),"Generation ofinfluenza A virusesentirely from cloned cDNAs,"Proceedingsofthe NationalAcademy of SciencesoftheUnitedStatesofAmerica,96,9345-9350.
  • Neumann,G.,M.T.Hughes,and Y.Kawaoka(12-15-2000),"Influenza A virus NS2 protein mediates vRNP nuclear export through NES-independentinteraction with hCRM1,"EMBO Journal,19, 6751-6758.
  • Nemeroff, M. E., S. M. Barabino, Y. Li, W. Keller, and R. M. Krug(1998),"Influenza virus NS1 protein interacts with the cellular30kDasubunitofCPSF andinhibits3'endformationof cellularpre-mRNAs,"MolecularCell,1,991-1000.
  • Nabel,G.J.and A.S.Fauci(2010),"Induction ofunnaturalimmunity: prospects fora broadly protective universalinfluenza vaccine," NatureMedicine,16,1389-1391.
  • Moules,V.,O.Terrier,M.Yver,B.Riteau,C.Moriscot,O.Ferraris,T. Julien, E. Giudice, J. P. Rolland, A. Erny, M. Bouscambert-Duchamp,E.Frobert,M.Rosa-Calatrava,Lin Y. Pu,A.Hay,D.Thomas,G.Schoehn,and B.Lina(5-25-2011), "Importance of viral genomic composition in modulating glycoprotein contenton thesurfaceofinfluenzavirusparticles," Virology,414,51-62.
  • Moskophidis, D. and D. Kioussis(7-20-1998), "Contribution of virus-specific CD8+ cytotoxic T cells to virus clearance or pathologicmanifestationsofinfluenzavirusinfectioninaT cell receptor transgenic mouse model," Journal of Experimental Medicine,188,223-232.
  • Moscona A.(2005), "Neuraminidase inhibitors for influenza," New EnglandJournalofMedicine,353:1363-1373.
  • Min,J.Y.,S.Li,G.C.Sen,and R.M.Krug(6-20-2007),"A siteon the influenza A virus NS1 protein mediates both inhibition of PKR activationandtemporalregulationofviralRNA synthesis," Virology,363,236-243.
  • Mahmood,K.,R.A.Bright,N.Mytle,D.M.Carter,C.J.Crevar,J.E. Achenbach, P. M. Heaton, T. M. Tumpey, and T. M. Ross(10-3-2008), "H5N1 VLP vaccine induced protection in ferrets against lethalchallenge with highly pathogenic H5N1 influenzaviruses,"Vaccine,26,5393-5399.
  • Lipatov,A.S.,S.Andreansky,R.J.Webby,D.J.Hulse,J.E.Rehg,S. Krauss,D.R.Perez,P.C.Doherty,R.G.Webster,and M.Y. Sangster(2005),"Pathogenesis of Hong Kong H5N1 influenza virusNS gene reassortantsin mice:theroleofcytokines and B- and T-cellresponses," JournalofGeneralVirology,86, 1121-1130.
  • Lee,L.Y.,L.A.Hado,C.Simmons,M.D.deJong,N.V.Chau,R. Schumacher,Y.C.Peng,A.J.McMichael,J.J.Farrar,G.L. Smith,A.R.Townsend,B.A.Askonas,S.Rowland-Jones,and T.Dong(2008),"MemoryT cellsestablishedbyseasonalhuman influenzaA infectioncross-reactwithavianinfluenzaA (H5N1) in healthy individuals," Journal of Clinical Investment, 118, 3478-3490.
  • Lambert,L.C.and A.S.Fauci(11-18-2010),"Influenza vaccines for thefuture,"New EnglandJournalofMedicine,363,2036-2044.
  • Lamb, R. A. and C. J. Lai(1980), "Sequence of interrupted and uninterrupted mRNAs and cloned DNA coding for the two overlapping nonstructuralproteins ofinfluenza virus,"Cell,21, 475-485.
  • Lamb R.A.,Krug R.M.(1996),"Orthomxyoviridae:The viruses and theirreplicatio,"Philadelphia,Lippincott-Raven.38. Lee,M.T.,K.Bishop,L.Medcalf,D.Elton,P.Digard,and L. Tiley(1-15-2002),"Definition of the minimalviralcomponents required for the initiation of unprimed RNA synthesis by influenza virus RNA polymerase,"Nucleic Acids Research,30, 429-438.
  • Lam,W.Y.,A.C.Yeung,I.M.Chu,and P.K.Chan(2010),"Profiles ofcytokineandchemokinegeneexpressioninhumanpulmonary epithelialcells induced by human and avian influenza viruses," VirologyJournal,,7,344-
  • Krug,R.M.,M.Bouloy,and S.J.Plotch(2-25-1980a),"RNA primers and the role ofhostnuclearRNA polymerase IIin influenza viralRNA transcription,"PhilosphicalTransaction ofthe Royal SocietyLondB BiologicalScience.,288,359-370.
  • Krug,R.M.,B.A.Broni,A.J.LaFiandra,M.A.Morgan,and A.J. Shatkin(1980b),"Priming and inhibitory activities ofRNAs for theinfluenzaviraltranscriptasedonotrequirebasepairingwith the virion template RNA," Proceedings of the National Academy ofSciences ofthe United States ofAmerica,77, 5874-5878.
  • Kreijtz,J.H.,Y.Suezer,Mutsert G.de,J.M. van den Brand, Amerongen G.van,B.S.Schnierle,T.Kuiken,R.A.Fouchier, J. Lower, A. D. Osterhaus, G. Sutter, and G. F. Rimmelzwaan(10-23-2009),"Preclinicalevaluation ofa modified vaccinia virus Ankara (MVA)-based vaccine againstinfluenza A/H5N1viruses,"Vaccine,27,6296-6299.
  • Kreijtz,J.H.,MutsertG.de,C.A.vanBaalen,R.A.Fouchier,A.D. Osterhaus,and G.F.Rimmelzwaan(2008),"Cross-recognition of avian H5N1 influenza virus by human cytotoxic T-lymphocyte populations directed to human influenza A virus," Journalof Virology,82,5161-5166.
  • Kochs,G.,A.Garcia-Sastre,and L.Martinez-Sobrido(2007),"Multiple anti-interferon actions ofthe influenza A virus NS1 protein," JournalofVirology,81,7011-7021.
  • Kim,E.H.,P.N.Pascua,M.S.Song,Y.H.Baek,H.I.Kwon,S.J. Park,G.J.Lim,S.M.Kim,A.Decano,K.J.Lee,W.K.Cho, J. Y. Ma, and Y. K. Choi(2013), "Immunomodulaton and attenuation of lethal influenza A virus infection by oral administrationwithKIOM-C,"AntiviralResearch,98,386-393.
  • Jones,L.D.and P.A.Nuttall(1989),"Non-viraemic transmission of Thogotovirus:influenceoftimeand distance,"Transactionsof the Royal Society of tropical Medicine and Hygiene, 83, 712-714.
  • Jakeman,K.J.,M.Tisdale,S.Russell,A.Leone,and C.Sweet(1994), "Efficacyof2'-deoxy-2'-fluororibosidesagainstinfluenzaA and B viruses in ferrets,"AntimicrobialAgentsand Chemotherapy, 38,1864-1867.
  • Jackson,D.,M.J.Hossain,D.Hickman,D.R.Perez,and R.A. Lamb(3-18-2008),"A new influenzavirusvirulencedeterminant: the NS1 protein four C-terminal residues modulate pathogenicity," Proceedings of the National Academy of SciencesoftheUnitedStatesofAmerica,105,4381-4386.
  • Iwatsuki-Horimoto,K.,T.Horimoto,Y.Fujii,and Y.Kawaoka(2004), "Generation ofinfluenza A virus NS2 (NEP)mutants with an alterednuclearexportsignalsequence,"JournalofVirology,78, 10149-10155.
  • Ito, T., O. T. Gorman, Y. Kawaoka, W. J. Bean, and R. G. Webster(1991),"Evolutionary analysis ofthe influenza A virus M genewith comparison oftheM1and M2proteins,"Journal ofVirology,65,5491-5498.
  • Isoda,N.,Y.Sakoda,N.Kishida,K.Soda,S.Sakabe,R.Sakamoto,T. Imamura,M.Sakaguchi,T.Sasaki,N.Kokumai,T.Ohgitani,K. Saijo,A.Sawata,J. Hagiwara, Z. Lin, and H. Kida(2008), "Potencyofaninactivatedavianinfluenzavaccinepreparedfrom a non-pathogenic H5N1 reassortant virus generated between isolatesfrom migratory ducksin Asia,"ArchivesVirology,153, 1685-1692.
  • Hyland, L., R. Webby, M. R. Sandbulte, B. Clarke, and S. Hou(5-25-2006),"Influenza virus NS1 protein protects against lymphohematopoietic pathogenesis in an in vivo mouse model," Virology,349,156-163.
  • Hoft,D.F.,E.Babusis,S.Worku,C.T.Spencer,K.Lottenbach,S.M. Truscott,G.Abate,I.G.Sakala,K.M.Edwards,C.B.Creech, M.A.Gerber,D.I.Bernstein,F.Newman,I.Graham,E.L. Anderson,and R.B.Belshe(9-15-2011),"Live and inactivated influenza vaccines induce similar humoralresponses,butonly live vaccines induce diverse T-cell responses in young children,"JournalofInfectiousDisease,204,845-853.
  • Heiny,A.T.,O.Miotto,K.N.Srinivasan,A.M.Khan,G.L.Zhang, V.Brusic,T.W.Tan,and J.T.August(2007),"Evolutionarily conserved protein sequences ofinfluenza a viruses,avian and human,asvaccinetargets,"PlosOne,2,e1190-
  • Heikkinen,L.S.,A.Kazlauskas,K.Melen,R.Wagner,T.Ziegler,I. Julkunen,and K.Saksela(2-29-2008),"Avian and 1918 Spanish influenzaavirusNS1proteinsbind toCrk/CrkL Srchomology 3domainstoactivatehostcellsignaling,"JournalofBiological Chemistry,283,5719-5727.
  • He,X.S.,T.H.Holmes,C.Zhang,K.Mahmood,G.W.Kemble,D.B. Lewis,C.L.Dekker,H.B.Greenberg,and A.M.Arvin(2006), "Cellular immune responses in children and adults receiving inactivated or live attenuated influenza vaccines," Journalof Virology,80,11756-11766.
  • Hale,B.G.,R.E.Randall,J.Ortin,and D.Jackson(2008),"The multifunctionalNS1 protein ofinfluenza A viruses,"Journalof GeneralVirology,89,2359-2376.
  • Hale, B. G., R. A. Albrecht, and A. Garcia-Sastre(2010), "Innate immune evasion strategies of influenza viruses," Future.Microbiology,5,23-41.
  • Hale, B. G., D. Jackson, Y. H. Chen, R. A. Lamb, and R. E. Randall(9-19-2006), "Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling," ProceedingsoftheNationalAcademyofSciencesoftheUnited StatesofAmerica,103,14194-14199.
  • Gubareva, L. V., S. G. Markushin, N. L. Barich, and N. V. Kaverin(1988),"RoleoftheNS geneinregulating thesynthesis of RNA-segments of the influenza A virus," Molekuliarnaia GenenetikaMikrobiolgiiaIVirusologiia,38-42.
  • Govorkova,E.A.,R.J.Webby,J.Humberd,J.P.Seiler,and R.G. Webster(7-15-2006), "Immunization with reverse-genetics-produced H5N1 influenza vaccine protects ferretsagainsthomologousandheterologouschallenge,"Journal ofInfectiousDisease,194,159-167.
  • Gorai,T.,H.Goto,T.Noda, T.Watanabe,H.Kozuka-Hata, M. Oyama, R. Takano, G. Neumann, S. Watanabe, and Y. Kawaoka(3-20-2012), "F1Fo-ATPase, F-type proton-translocatingATPase,attheplasmamembraneiscritical for efficient influenza virus budding," Proceedings of the NationalAcademyofSciencesoftheUnitedStatesofAmerica, 109,4615-4620.
  • Garcia-Sastre,A.,A.Egorov,D.Matassov,S.Brandt,D.E.Levy,J. E.Durbin,P.Palese,and T.Muster(12-20-1998),"Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems,"Virology,252,324-330.
  • Gack,M.U.,R.A.Albrecht,T.Urano,K.S.Inn,I.C.Huang,E. Carnero, M. Farzan, S. Inoue, J. U. Jung, and A. Garcia-Sastre(5-8-2009),"Influenza A virus NS1 targets the ubiquitin ligaseTRIM25to evaderecognition by thehostviral RNA sensorRIG-I,"CellHostandMicrobe,5,439-449.
  • Forbes,N.E.,J.Ping,S.K.Dankar,J.J.Jia,M.Selman,L.Keleta, Y.Zhou,and E.G.Brown(2012),"MultifunctionaladaptiveNS1 mutationsareselected upon human influenzavirusevolution in themouse,"PlosOne,7,e31839.
  • Fodor,E.,L.Devenish,O.G.Engelhardt,P.Palese,G.G.Brownlee, and A.Garcia-Sastre(1999),"Rescueofinfluenza A virusfrom recombinantDNA,"JournalofVirology,73,9679-9682.
  • Enami,M.,W.Luytjes,M.Krystal,and P.Palese(1990),"Introduction ofsite-specific mutations into the genome ofinfluenza virus," ProceedingsoftheNationalAcademyofSciencesoftheUnited StatesofAmerica,87,3802-3805.
  • Ehrhardt,C.,T.Wolff,S.Pleschka,O.Planz,W.Beermann,J.G. Bode,M.Schmolke,and S.Ludwig(2007),"Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses," Journal of Virology., 81, 3058-3067.
  • Egorov,A.,S.Brandt,S.Sereinig,J.Romanova,B.Ferko,D.Katinger, A. Grassauer, G. Alexandrova, H. Katinger, and T. Muster(1998), "Transfectant influenza A viruses with long deletions in the NS1 protein grow efficiently in Vero cells," JournalVirology,72,6437-6441.
  • De Jong,M.D.,C.P.Simmons,T.T.Thanh,V.M.Hien,G.J. Smith,T.N.Chau,D.M.Hoang,N.V.Chau,T.H.Khanh,V. C.Dong,P.T.Qui,B.V.Cam,doQ.Ha,Y.Guan,J.S.Peiris, N.T.Chinh,T.T.Hien,andJ.Farrar(2006),"Fataloutcomeof human influenza A (H5N1)is associated with high viralload andhypercytokinemia,"NatureMedicine.,12,1203-1207.
  • Dankar,S.K.,S.Wang,J.Ping,N.E.Forbes,L.Keleta,Y.Li,andE. G.Brown(2011),"InfluenzaA virusNS1genemutationsF103L andM106Iincreasereplicationandvirulence,"VirologyJournal., 8,13.
  • Connor, R. J., Y. Kawaoka, R. G. Webster, and J. C. Paulson(11-15-1994),"Receptorspecificity in human,avian,and equine H2 and H3 influenza virus isolates," Virology, 205, 17-23.
  • Conenello,G.M.,D.Zamarin,L.A.Perrone,T.Tumpey,and P. Palese(10-5-2007b),"A singlemutation in thePB1-F2ofH5N1 (HK/97)and 1918 influenza A viruses contributes to increased virulence,"PlosPathogens.,3,1414-1421.
  • Conenello, G. M. and P. Palese(10-11-2007a), "Influenza A virus PB1-F2:a smallprotein with a big punch," CellHost and Microbe,2,207-209.
  • Colman,P.M.and M.C.Lawrence(2003),"Thestructuralbiology of typeIviralmembranefusion,"NatureReviewsMolecularCell Biology,4,309-319.
  • Claas,E.C.,A.D.Osterhaus,Beek R.van,J.C.De Jong,G.F. Rimmelzwaan,D.A.Senne,S.Krauss,K.F.Shortridge,andR. G.Webster(2-14-1998),"HumaninfluenzaA H5N1virusrelated to a highly pathogenic avian influenza virus," Lancet, 351, 472-477.
  • Chen,Z.and R.M.Krug(2000),"Selective nuclear export of viral mRNAs in influenza-virus-infected cells," Trends in Microbiology.,8,376-383.
  • Chen,Z.,Y.Li,and R.M.Krug(4-15-1999),"Influenza A virusNS1 protein targetspoly(A)-binding protein IIofthecellular3'-end processingmachinery,"EMBO Journal,18,2273-2283.
  • Chen,Z.,L.Kim,K.Subbarao,and H.Jin(3-28-2012),"The 2009 pandemic H1N1 virus induces anti-neuraminidase (NA) antibodies thatcross-reactwith the NA ofH5N1 viruses in ferrets,"Vaccine,30,2516-2522.
  • Cattoli,G.,I.Monne,A.Fusaro,T.M.Joannis,L.H.Lombin,M.M. Aly,A.S.Arafa,K.M.Sturm-Ramirez,E.Couacy-Hymann,J. A.Awuni,K.B.Batawui,K.A.Awoume,G.L.Aplogan,A. Sow,A.C.Ngangnou,I.M.ElNasriHamza,D.Gamatie,G. Dauphin, J. M. Domenech, and I. Capua(2009), "Highly pathogenic avian influenza virus subtype H5N1 in Africa:a comprehensive phylogenetic analysis and molecular characterizationofisolates,"PlosOne,4,e4842-
  • Castrucci,M.R.,I.Donatelli,L.Sidoli,G.Barigazzi,Y.Kawaoka,and R.G.Webster(1993),"Genetic reassortmentbetween avian and human influenza A viruses in Italian pigs," Virology, 193, 503-506.
  • Brewoo,J.N.,T.D.Powell,J.C.Jones,N.A.Gundlach,G.R.Young, H.Chu,S.C.Das,C.D.Partidos,D.T.Stinchcomb,andJ.E. Osorio(4-3-2013),"Cross-protective immunity against multiple influenza virus subtypes by a novelmodified vaccinia Ankara (MVA)vectoredvaccineinmice,"Vaccine,31,1848-1855.
  • Bragstad,K.,P.H.Jorgensen,K.Handberg,A.S.Hammer,S.Kabell, andA.Fomsgaard(2007),"Firstintroductionofhighlypathogenic H5N1avian influenza A virusesin wild and domesticbirdsin Denmark,NorthernEurope,"VirologyJournal,4,43.
  • Bouvier,N.M.and P.Palese(9-12-2008),"The biology ofinfluenza viruses,"Vaccine,26Suppl4,D49-D53.
  • Bodewes,R.,J.H.Kreijtz,M.M.Geelhoed-Mieras,AmerongenG.van, R.J.Verburgh,S.E.van Trierum,T.Kuiken,R.A.Fouchier, A.D.Osterhaus,and G.F.Rimmelzwaan(2011),"Vaccination againstseasonalinfluenza A/H3N2 virus reduces the induction of heterosubtypic immunity against influenza A/H5N1 virus infectioninferrets,"JournalofVirology,85,2695-2702.
  • Bodewes,R.,J.H.Kreijtz,C.Baas,M.M.Geelhoed-Mieras,Mutsert G.de,AmerongenG.van,J.M.vandenBrand,R.A.Fouchier, A.D.Osterhaus,and G.F.Rimmelzwaan(2009),"Vaccination againsthumaninfluenzaA/H3N2viruspreventstheinductionof heterosubtypic immunity against lethal infection with avian influenzaA/H5N1virus,"PlosOne.,4,e5538-
  • Bergmann, M., A. Garcia-Sastre, E.Carnero, H.Pehamberger,K. Wolff,P.Palese,and T.Muster(2000),"Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication," JournalofVirology.,74,6203-6206.
  • Beigel,J.H.,J.Farrar,A.M.Han,F.G.Hayden,R.Hyer,M.D.de Jong,S.Lochindarat,T.K.Nguyen,T.H.Nguyen,T.H.Tran, A. Nicoll, S. Touch, and K. Y. Yuen(9-29-2005), "Avian influenzaA (H5N1)infectioninhumans,"New EnglandJournal ofMedicine,353,1374-1385.
  • Alonso-Caplen,F.V.,M.E.Nemeroff,Y.Qiu,andR.M.Krug(1992), "Nucleocytoplasmic transport:the influenza virus NS1 protein regulatesthetransportofsplicedNS2mRNA anditsprecursor NS1mRNA,"GenesandDevelopment.,6,255-267.
  • Air,G.M.(1981),"Sequence relationships among the hemagglutinin genesof12subtypesofinfluenzaA virus,"Proceedingsofthe NationalAcademyofSciencesoftheUnitedStatesofAmerica, 78,7639-7643.